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Health-related quality of life in children with objectively diagnosed staple food allergy assessed with a disease-specific questionnaire
Karolinska Inst.
Karolinska Inst ; Umea Univ.
Karolinska Inst ; Södersjukhuset Stockholm.
SBU ;Karolinska Inst, Dept Learning Informat Management & Eth ; Karolinska Inst.
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2015 (Engelska)Ingår i: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 104, nr 10, s. 1047-1054Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Aim: Among Swedish children of 0-12 years old, we investigated various food allergy-related exposures associated with health-related quality of life using a food allergy-specific questionnaire among children allergic to the staple foods cow's milk, hen's egg and/or wheat, and contextualised worse food allergy-associated health-related quality of life using a generic questionnaire versus controls. Methods: In total, 85 children with objectively diagnosed allergy to the staple foods were included as cases, and 94 children matched for age and sex were included as controls. We administered a food allergy-specific parent-completed questionnaire originally developed by EuroPrevall to cases only, and a generic health-related quality of life questionnaire (EuroQol Health Questionnaire, 5 Dimensions; EQ 5-D); to both cases and controls. Results: Hen's egg was the most common offending staple food, affecting 76% of cases. Approximately 7% of cases were allergic to all three staple foods. Parent-reported respiratory and cardiovascular symptoms were associated with worse health-related quality of life. Elements of disease severity [previous anaphylaxis (p < 0.001); epinephrine autoinjector prescription (p < 0.003)] were negatively associated with health-related quality of life. Cases had worse health-related quality of life measured by the EQ-5D compared to controls (p < 0.01). Conclusion: The use of a disease-specific questionnaire revealed that disease severity in children with objectively diagnosed allergy to the staple foods cow's milk, hen's egg and/or wheat is associated with worse health-related quality of life. The use of a generic questionnaire confirmed that cases have worse health-related quality of life than controls.

Ort, förlag, år, upplaga, sidor
2015. Vol. 104, nr 10, s. 1047-1054
Nyckelord [en]
Children, Food allergy, Food hypersensitivity Health-related quality of life
Nationell ämneskategori
Omvårdnad
Forskningsämne
Hälsovetenskap
Identifikatorer
URN: urn:nbn:se:lnu:diva-46976DOI: 10.1111/apa.13044ISI: 000362512100025PubMedID: 25983039Scopus ID: 2-s2.0-84941942146OAI: oai:DiVA.org:lnu-46976DiVA, id: diva2:866063
Tillgänglig från: 2015-10-30 Skapad: 2015-10-30 Senast uppdaterad: 2017-12-01Bibliografiskt granskad

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