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The toxins of nemertean worms
Uppsala University. (Department of Pharmacognosy)ORCID iD: 0000-0002-5005-9612
Uppsala University. (Department of Pharmacognosy)
Swedish University of Agricultural Sciences. (Sven Lovén Centre for Marine Sciences)ORCID iD: 0000-0002-8144-9592
Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences. (Linnaeus Ctr Biomat Chem, BMC)ORCID iD: 0000-0003-1241-8888
2019 (English)In: Toxins, ISSN 2072-6651, E-ISSN 2072-6651, Vol. 11, no 2, p. 1-36, article id 120Article in journal (Refereed) Published
Abstract [en]

Most ribbon worms (phylum: Nemertea) are found in marine environments, where they act as predators and scavengers. They are characterized by an eversible proboscis that is used to hunt for prey and thick mucus covering their skin. Both proboscis and epidermal mucus mediate toxicity to predators and preys. Research into the chemical nature of the substances that render toxicity has not been extensive, but it has nevertheless led to the identification of several compounds of potential medicinal use or for application in biotechnology. This review provides a complete account of the current status of research into nemertean toxins.

Place, publisher, year, edition, pages
MDPI, 2019. Vol. 11, no 2, p. 1-36, article id 120
Keywords [en]
Anabaseine, cytotoxin, DMXBA, nemertea, nemertide, parborlysin, ribbon worm, tetrodotoxin
National Category
Pharmacology and Toxicology
Research subject
Biomedical Sciences, Pharmacology; Natural Science, Cell and Organism Biology; Biomedical Sciences, Pharmacology; Chemistry, Biochemistry
Identifiers
URN: urn:nbn:se:lnu:diva-80740DOI: 10.3390/toxins11020120ISI: 000460801500062PubMedID: 30781381Scopus ID: 2-s2.0-85061849853OAI: oai:DiVA.org:lnu-80740DiVA, id: diva2:1290586
Funder
Swedish Research Council, 214-3327Swedish Research Council Formas, 2018-00613The Crafoord Foundation, 20160810Swedish Research Council, 2018-005403Available from: 2019-02-21 Created: 2019-02-21 Last updated: 2019-08-29Bibliographically approved

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Andersson, Håkan S.

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