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Precipitant Factors of Heart Failure Decompensation in Patients Attended in Primary Care, the Hefestos Study
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2019 (English)In: Circulation, ISSN 0009-7322, E-ISSN 1524-4539, Vol. 140, article id A10647Article in journal, Meeting abstract (Refereed) Published
Abstract [en]

Introduction: Most knowledge about the main causes of heart failure decompensation come from hospital setting. However, evidence coming from primary care is scarce.

Hypothesis: It is possible to identify the main causes of decompensation of HF in order to prevent and treat them

Methods: HEFESTOS is a multinational collaborative cohort study carried out in 10 European countries, aimed at knowing the main precipitant factors related to a heart failure decompensation, attended in primary care setting and its relationship to the prognosis at short term. Patients were consecutively recruited and followed for one month after the decompensation

Results: 685 patients were prospectively included. Women represented 54.5% and mean age was 81.2 (DE 8.90) years. Potential causative factors for decompensated heart failure were identified in 77.9 % of cases. More than one factor was identified in 35.9% of patients. Respiratory infections, Non-compliance with fluid or salt restriction, non-medication adherence, and atrial fibrillation, were the most commonly identified factors (28.2%, 26.8%, 22.8% and 14.5%, respectively). A total of 28.2% of patients were hospitalized and 3.5% died. After adjusting for potential confounding factors, only respiratory infections and atrial fibrillation were significantly associated with hospitalization or mortality (OR 1.19, 95%CI 1.09-1.19 and 1.22, 95%CI, 1.10-1.35), respectively

Conclusions: An early identification and treatment of respiratory infection and atrial fibrillation would help to prevent hospitalizations and mortality in heart failure patients presenting heart failure decompensation.

Place, publisher, year, edition, pages
2019. Vol. 140, article id A10647
National Category
Cardiac and Cardiovascular Systems
Research subject
Natural Science, Medicine
Identifiers
URN: urn:nbn:se:lnu:diva-90812OAI: oai:DiVA.org:lnu-90812DiVA, id: diva2:1384181
Conference
the American Heart Association's 2019 Scientific Sessions
Available from: 2020-01-09 Created: 2020-01-09 Last updated: 2020-01-15Bibliographically approved

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Thulesius, Hans

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CiteExportLink to record
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Citation style
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