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Older Swedish Adults with High Self-Perceived Health Show Optimal 25-Hydroxyvitamin D Levels Whereas Vitamin D Status Is Low in Patients with High Disease Burden
Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry. Cty Hosp Kalmar.ORCID iD: 0000-0003-3106-0754
Cty Hosp Kalmar.
Linköping University ; Cty Hosp Kalmar.
Cty Hosp Kalmar.
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2016 (English)In: Nutrients, ISSN 2072-6643, E-ISSN 2072-6643, Vol. 8, no 11, 717Article in journal (Refereed) Published
Abstract [en]

Controversy pervades the definition of adequate and optimal vitamin D status. The Institutes of Medicine have recommended serum 25(OH) D levels above 50 nmol/L based upon evidence related to bone health, but some experts, including the Endocrine Society and International Osteoporosis Foundation, suggest a minimum serum 25(OH) D level of 75 nmol/L to reduce the risk of falls and fractures in older adults. In a cross-sectional study, we compared vitamin D status in people >= 75 years selected from four groups with a frailty phenotype, combined with a control group free from serious illness, and who considered themselves completely healthy. Only 13% of the 169 controls were vitamin D deficient (S-25(OH) D) < 50 nmol/L), in contrast with 49% of orthopedic patients with hip fractures (n = 133), 31% of stroke patients (n = 122), 39% of patients visiting the hospital's emergency department >= 4 times a year (n = 81), and 75% of homebound adult residents in long-term care nursing homes (n = 51). The mean vitamin D concentration of the healthy control group (74 nmol/L) was similar to a suggested optimal level based on physiological data and mortality studies, and much higher than that of many officially recommended cut-off levels for vitamin D deficiency (< 50 nmol/L). The present study provides a basis for planning and implementing public guidelines for the screening of vitamin D deficiency and vitamin D treatment for frail elderly patients.

Place, publisher, year, edition, pages
2016. Vol. 8, no 11, 717
Keyword [en]
vitamin D, 25-hydroxyvitamin D, Sweden, emergency care, frail older adult
National Category
Nutrition and Dietetics
Research subject
Natural Science, Medicine
Identifiers
URN: urn:nbn:se:lnu:diva-59470DOI: 10.3390/nu8110717ISI: 000388666400051OAI: oai:DiVA.org:lnu-59470DiVA: diva2:1059768
Available from: 2016-12-23 Created: 2016-12-23 Last updated: 2017-03-13Bibliographically approved

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Carlsson, MartinEricson, LisaPetersson, Göran
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CiteExportLink to record
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Citation style
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