In this paper we present opportunities and challenges to meet the worldwide challenge of diabetes. Diabetes has devastating long-term complications that cause very great personal suffering and social costs locally and globally. The prevalence of diabetes is increasing globally as an epidemic and affects 415 million people today, which is expected to increase to 642 million in 2040. In this paper we explore possibilities to join in Indo-Swedish R&D collaboration. We present and motivate the research purpose. Furthermore we present a research framework for mobile application development between Sweden and India. The scientific framework is elaborated and this paper ends with specific challenges and further work.