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Kadmium och preeklampsi - finns det något samband? En litteraturstudie
Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
2018 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesisAlternative title
Cadmium and preeclampsia – is there any connection? A literature study (English)
Abstract [sv]

Bakgrund: Kadmium (Cd) är ett metalliskt grundämne med välkända negativa hälsoeffekter som vi exponeras för i vår miljö, till stor del genom kosten. Preeklampsi drabbar årligen 3-7 % av alla gravida kvinnor och är en av de vanligaste orsakerna till sjuklighet och dödlighet för modern och en stor orsak till prematuritet och hämmad fostertillväxt.

Syfte: Syftet med studien var att undersöka om det finns något samband mellan Cd och preeklampsi och i så fall vad sambandet/sambanden kan vara.

Metod: Arbetet är en litteraturstudie baserad på vetenskapliga artiklar som sammanfattats.

Resultat: Samtliga sju artiklar visar ett samband mellan Cd och preeklampsi. I experimentella modeller på dräktiga råttor som exponeras för Cd så utvecklar råttorna karakteristika för preeklampsi inklusive högt blodtryck. Hos människor observeras signifikanta samband mellan preeklampsi och högre Cd-halter i blod, serum samt fostervatten.

Slutsats: Artiklarna visar att det finns ett samband mellan Cd och preeklampsi även om det inte går att fastställa att det rör sig om direkta orsakssamband utan fortsatt forskning.

Abstract [en]

Background: Cadmium (Cd) is a metallic element with well-known negative health effects that we are exposed to in our environment, largely through diet. Preeclampsia annually affects 3-7% of all pregnant women and is one of the most common causes of morbidity and mortality for the mother and a major cause of prematurity and fetal growth retardation.

Purpose: The purpose of the study was to investigate whether there is any correlation between Cd and preeclampsia and, if so, what the connection may be.

Method: This study is a literature review based on scientific articles summarized.

Results: All seven articles show a correlation between Cd and preeclampsia. In experimental models on pregnant rats exposed to Cd, rats develop characteristics of preeclampsia including high blood pressure. In humans, significant association between preeclampsia and higher Cd levels are observed in blood, serum and amniotic fluid.

Conclusion: The articles show that there is a correlation between Cd and preeclampsia, although it cannot be established that it is a direct causal link without further research.

Place, publisher, year, edition, pages
2018. , p. 36
Keywords [sv]
Kadmium, preeklampsi
National Category
Medical and Health Sciences Other Health Sciences Other Medical Sciences not elsewhere specified
Identifiers
URN: urn:nbn:se:lnu:diva-71220OAI: oai:DiVA.org:lnu-71220DiVA, id: diva2:1187038
Educational program
Health Science Programme with Specialisation in Bio Sciences, 180 credits
Supervisors
Examiners
Available from: 2018-03-02 Created: 2018-03-02 Last updated: 2018-03-02Bibliographically approved

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CiteExportLink to record
Permanent link

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Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
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Language
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  • fi-FI
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  • sv-SE
  • Other locale
More languages
Output format
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