The article delineates a model of communication among human mindsthat is designed to work equally well for all kinds of nonverbal and verbal significance.The model thus allows for detailed analysis of and comparison among allvarieties of human communication. In particular, the transitional stage of communication,which is termed the media product, is thoroughly developed andconceptualized in terms of mediality and semiosis. By way of mapping basic mediadissimilarities that are vital for differing communicative capacities, the modelexplains both how various sorts of significance can be transferred among minds,and why they cannot always be realized. The article furthermore suggests a semioticframework for conceptualizing the familiar notion that communication is alsostrongly predisposed by surrounding factors such as earlier experiences and culturalinfluence.