The feasibility of manufacturing phosphatebonded wood composite board products from four locallyoccurring invasive acacia tree species (Acacia cyclops, A.saligna, A. mearnsii and A. longifolia) was studied usinga formulated magnesium oxide (MgO) and monopotassiumphosphate (KH2PO4) binder system. The optimizationfor the manufacturing process was studied using a centralcomposite statistical design, whereupon the following factorswere considered, i.e. KH2PO4:MgO ratio, the fly ashcontent as partial replacement for the binder and the woodcontent as a ratio of wood to the total inorganic content.A fitted response surface plot was used to show the effectof the main factors and their interactions on the measuredboard properties. A response surface model was developedto predict the parameters leading to the best board properties.All physical properties evaluated met or exceededthe minimum requirements for low density particleboards.The results showed that the variables considered have significanteffects on the physical properties of the boards.The optimum composite manufacturing process for makingdurable products within the scope of the studied specieswas found to be a KH2PO4/MgO ratio of 1.66, an ashcontent of 2.7% and a wood/inorganic ratio of 0.96 for theselected wood species.