The statement ‘Data is the new oil’ has been broadly acknowledged due to its wide-ranging importance. Utilizing big data offers a variety of benefits. Although the health sector was late in terms of exploiting the benefits of big data, currently, the adoption is accelerating. Healthcare is increasingly becoming an information science and the implementation of electronic medical records (EMR) and other information systems is growing rapidly. The patient data originating from smart devices and other sources like genomic databases are supporting the healthcare sector offering better healthcare delivery and increasing efficiency, hence saving costs. This study was conducted to analyze this process closer focusing on a case of Cardiology. Conducting a comprehensive literature review and qualitative expert interviews, the impact of big data in the field of Cardiology was explored. The result of the study shows that big data can play a positive role in three aspects: prediction of disease, prevention of disease and management of disease. Big data enables us to build models that can be used to predict the occurrence of disease. Based on this information, actions can be taken to prevent the disease. Data also helps to manage the disease by offering helpful insights. Medical personnel can retrieve the patient data, with the help of AI, they can make faster decisions allowing them to spend more quality time with the patients and reduce cognitive errors. Through the interviews, it was understood that even though the positive role of big data has been acknowledged, the implementation is still a challenge due to various limitations. The challenges lied mainly on technical know-how and domain knowledge. Further challenges were data security and privacy issues that need to be addressed to mitigate the risks that can be caused by them. The examples of big data implementation in various cases like in heart failure prediction or prevention shows a positive picture. The overwhelming majority of case studies analyzed in this regard show an optimistic picture. Due to growing importance and use of smart devices, IoT, genomics and the recent developments in the field of ICTs, it is expected that big data will not only leave a positive influence on the field of Cardiology, it will also change the way medicine is practiced and healthcare is offered.