This chapter aims at highlighting the benefit of numerical methods and their broad application in the field of wood, engineered wood-based products (EWPs), structural elements including glued-laminated and cross-laminated timber, and engineered timber structures. It focuses on the hygrothermo- viscoelastic material behavior of these elements and structures as a consequence of the behavior of wood materials. After motivating the need for models of wood, different types of numerical models and their application for determination of mechanical properties and dimensional stability of wooden boards, strand- and veneer-based engineered woodbased products, including glued-laminated and crosslaminated timber, as well as of connections in EWPs are reviewed and application examples are given. Methods and application examples are furthermore provided for moisturerelated stresses and deformations in timber structures, the influence of connections on the structural response, instability of structural systems, and modeling of prefabricated frame structures, before modeling of historical structures of wood is discussed. The chapter ends with discussing bottlenecks in modeling of wood materials and timber structures, which might be a starting point for further improvements and novel modeling strategies. © Springer Nature Switzerland AG 2023.