This paper aims to conduct an interdisciplinary systematic literature review of fake news research and to advance the socio-technical understanding of digital information practices and platforms in business and management studies. The paper applies a focused, systematic literature review method to analyze articles on fake news in business and management journals from 2010 to 2020. The paper analyzes the definition, theoretical frameworks, methods, and research gaps of fake news in the business and management domains. It also identifies some promising research opportunities for future scholars. The paper offers practical implications for various stakeholders who are affected by or involved in fake news dissemination, such as brands, consumers, and policymakers. It provides recommendations to cope with the challenges and risks of fake news. The paper discusses the social consequences and future threats of fake news, especially in relation to social networking and social media. It calls for more awareness and responsibility from online communities to prevent and combat fake news. The paper contributes to the literature on information management by showing the importance and consequences of fake news sharing for societies. It is among the frontier systematic reviews in the field that cover studies from different disciplines and focus on business and management studies.