Lost in Limehouse or Lady Esmerelda's Predicament (1933).  This American short film directed by Otto Brower (1890–1946) parodies both Conan Doyle’s Sherlock Holmes stories and Sax Rohmer’s Fu-Manchu series. In the film, the young lady Esmeralda has been kidnapped by the villainous Sir Marmaduke Rakes. Allied with a Chinese Tong gang led by a man by the name of Hoo Flung, Rakes keeps Esmeralda prisoner in an opium den over which hangs the sign “Limhouse”.