History anticipates a link between religion and innovation, and religious aspects could be expected to impact also current innovation activities, positive or negative. This paper describes and discusses the relations between innovation and religion by means of a systematic literature review. The review points to six different causal claims between religion and innovation: (i) the Church as a platform for innovation and entrepreneurship; (ii) religion enablingor inhibiting innovation adaptation and diffusion; (iii) spirituality and ethics, and their relation to innovation, organisational development and human relation management; (iv) creation and utilisation of innovations in religious settings;(v) doctrinal innovation; and (vi) religion as scientific underpinning. Thise vokes an initiative for further studies on religion and innovation, and contributes to current understanding through providing a first-of-its kind literature review.