The paper presents ethical and legal challenges of holographic communication technologies and suggests a framework to address them. Holographic communications enable the capturing of a user’s 3D depiction via special equipment, and its high-quality transmission to another user located elsewhere, introducing a distinctive data communication experience. Their wrongful use could compromise basic human rights. Qualitative research was conducted through interviews with ethics and legal experts in Sweden and Greece, and document analysis. The collected data were analyzed thematically and discussed within the framework of Ethical Technology Assessment (eTA). The findings show that the main challenges are privacy and data protection. The design phase and users’ participation in the process of the development of holographic communication technologies were found to have a vital role in the ethical and respectful of the law use of them. Similar challenges and frameworks of existing technologies can serve as the basis to develop a new framework. Challenges in formulating a common framework, though, due to contextual, societal and geographical differences were also found. Thus, the research contributes to the informatics field by providing insights and extending the knowledge about the use of holographic communication technologies. It contributes practically to designers, developers, technology companies, and other interested stakeholders as it shortens the knowledge gap concerning the prospective ethical and legal issues posed by this technology and provides suggestions of an ethical-legal framework to address them.