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Finns Candidatus Neoehrlichia mikurensis bland fågelburna fästingar?
Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
2012 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Candidatus Neoehrlichia mikurensis is the causative agent of a recently discovered tick-borne disease. This bacterium is known to infect different types of rodents and can be transferred occasionally, by ticks, to humans. Thus far only six human cases are documented, and of them five individuals were immunosuppressed. Symptoms characteristic for Ca. Neoehrlichia mikurensis is persistent fever, arthralgia, myalgia and coagulation disorders. To increase our understanding of the host range of this disease we sampled 552 ticks from birds at Ottenby birdstation, Öland. Samples were screened utilizing real time-PCR for Ca. Neoehrlichia mikurensis 16S rRNA gene and positive samples were further analyzed for the bacteria’s GroEL-gene. The fragments from the bacteria’s 16S rRNA-gen were sequenced. Of the 552 analyzed ticks, 9 contained the bacterium resulting in a prevalence of 1,6 % and illustrating that Ca. Neoehrlichia mikurensis is present in ticks collected from birds. Hence, we can elucidate that birds may carry the bacterium as a number of the positive ticks belonged to the species Ixodes frontalis, which mainly parasitize birds.This study has contributed new information about Ca. Neoehrlichia mikurensis, particularly in regards to the host range, as ticks from birds never before have been studied for this purpose.

Place, publisher, year, edition, pages
2012. , 20 p.
National Category
Biomedical Laboratory Science/Technology
Identifiers
URN: urn:nbn:se:lnu:diva-20813OAI: oai:DiVA.org:lnu-20813DiVA: diva2:541139
Subject / course
Biomedical Sciences
Educational program
Biomedical Laboratory Science Programme, 180 credits
Uppsok
Medicine
Supervisors
Examiners
Available from: 2012-08-02 Created: 2012-07-14 Last updated: 2012-08-02Bibliographically approved

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