This paper presents results from a study of sexual prejudice and differentials in labor market outcomes due to sexual orientation. It uses data from a nationwide Swedish survey on public attitudes toward homosexuals, conducted in 1999, and combines them with register data for 2007, which include information about sexual orientation, employment status, and yearly earnings for the total population in Sweden. It finds that prejudice against homosexuals negatively affects the relative employment and relative earnings of gay men. Lesbians are affected negatively by prejudice against homosexuals in terms of employment, but the relationship is less clear in regard to earnings. Discrimination against homosexuals, as well as social norms, occupational sorting and self-selection in, geographic mobility are presented as explanations for the results.