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Thromboinflammation in therapeutic medicine
Uppsala university. (BMC)ORCID iD: 0000-0001-7888-1571
Univ Tokyo, Japan.
Uppsala university.
Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences. Uppsala University.
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2015 (English)In: Immune Responses to Biosurfaces / [ed] Lambris J., Ekdahl K., Ricklin D., Nilsson B., Springer, 2015, Vol. 865, 3-17 p.Conference paper, Published paper (Refereed)
Abstract [en]

Thromboinflammation is primarily triggered by the humoral innate immune system, which mainly consists of the cascade systems of the blood, i.e., the complement, contact/coagulation and fibrinolytic systems. Activation of these systems subsequently induces activation of endothelial cells, leukocytes and platelets, finally resulting in thrombotic and inflammatory reactions. Such reactions are triggered by a number of medical procedures, e.g., treatment with biomaterials or drug delivery devices as well as in transplantation with cells, cell clusters or whole vascularized organs. Here, we (1) describe basic mechanisms for thromboinflammation; (2) review thromboinflammatory reactions in therapeutic medicine; and (3) discuss emerging strategies to dampen thromboinflammation.

Place, publisher, year, edition, pages
Springer, 2015. Vol. 865, 3-17 p.
Series
Advances in Experimental Medicine and Biology, ISSN 0065-2598, E-ISSN 2214-8019
National Category
Immunology
Research subject
Biomedical Sciences, Immunology
Identifiers
URN: urn:nbn:se:lnu:diva-40421DOI: 10.1007/978-3-319-18603-0_1ISI: 000361838300002PubMedID: 26306440ISBN: 978-3-319-18602-3 (print)ISBN: 978-3-319-18603-0 (electronic)OAI: oai:DiVA.org:lnu-40421DiVA: diva2:790678
Conference
1st International Conference on Immune Response to Biosurfaces, Chania, GREECE, SEP 27-OCT 02, 2014
Available from: 2015-02-25 Created: 2015-02-25 Last updated: 2017-04-11Bibliographically approved

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CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
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