This investigation carried out in 2010, to study the effect of ethanol / cyclohexan extract for heart wood of Biota orientalis, Pinus pinea and Abies cilicica, in inhibition mycelium growth to fungi Alternaria alternate and Fusarium solani and compared with fungicides (thiophanate-m , chlorothalonil and mancozeb)  on PDA in laboratory. The obtained results showed that thiophanate-m gave the superior inhibition for F. solani ,where gave 100% inhibition at concentration 60 ppm. While the fungicide chlorothalonil gave the lowest inhibition to F. solani , where EC₅₀ (73 ppm). At contrast, the fungicide chlorothalonil gave the highest inhibition to A.alternate at used concentrates. Where cause 100% inhabition  at 100 ppm. Also the results showed that mancozeb gave moderate effect on both fungi, where EC50 37ppm an 58 ppm to F. solani and A. Alternate, respectively. On the other hand, the result showed that wood extract of study species gave significant inhibition to growth fungi compare with the control. the Ethanol/Cyclohexane-Extract of the heart wood of Biota orientales gave the superior effect inhibition to A. alternata ,where gave 100%  inhibition at 150 ppm. While the Ethanol/Cyclohexane-Extract of the heart wood of (Abies cilicica) gave the highest inhibition to F.solani , where the percentage inhibition at concentrate 125 ppm were 100%. In contrast,  the Ethanol/Cyclohexane-Extract of the heart wood of (Pinus pinea) gave moderate inhibition to A. Alternate, where EC₅₀ (94 ppm). While gave the lowest  effect in F. solani. Therefore we recommended to use the ethanol/ cyclohexane extract of the heart wood of Biota and Abies as Environment friendly fungicides.