This investigation has established the possibility of using Infra-density to determine the density of medium density fiber board (MDF). The statistical analysis has proved that there is a high significant correlation between the values of density and infra-density. There is a homogeneity between the method of density and infra-density measurements. Whereas the value of the correlation coefficient reached 0.85 and the mean of density 0.667 g/cm3 while the mean of infra-density was 0.668.