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Compilation of a standardised international folate database for EPIC.
International Agency for Research on Cancer, France.
Swedish University of Agricultural Sciences, Uppsala.ORCID iD: 0000-0003-0387-4312
International Agency for Research on Cancer, France.
International Agency for Research on Cancer, France.
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2016 (English)In: Food Chemistry, ISSN 0308-8146, E-ISSN 1873-7072, Vol. 193, p. 134-140Article in journal (Refereed) Published
Abstract [en]

This paper describes the methodology applied for compiling an "international end-user" folate database. This work benefits from the unique dataset offered by the European Prospective Investigation into Cancer and Nutrition (EPIC) (N=520,000 subjects in 23 centres). Compilation was done in four steps: (1) identify folate-free foods then find folate values for (2) folate-rich foods common across EPIC countries, (3) the remaining "common" foods, and (4) "country-specific" foods. Compiled folate values were concurrently standardised in terms of unit, mode of expression and chemical analysis, using information in national food composition tables (FCT). 43-70% total folate values were documented as measured by microbiological assay. Foods reported in EPIC were either matched directly to FCT foods, treated as recipes or weighted averages. This work has produced the first standardised folate dataset in Europe, which was used to calculate folate intakes in EPIC; a prerequisite to study the relation between folate intake and diseases.

Place, publisher, year, edition, pages
2016. Vol. 193, p. 134-140
National Category
Food Science
Research subject
Natural Science, Medicine
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URN: urn:nbn:se:lnu:diva-51160DOI: 10.1016/j.foodchem.2014.11.044PubMedID: 26433299OAI: oai:DiVA.org:lnu-51160DiVA, id: diva2:913565
Available from: 2016-03-21 Created: 2016-03-21 Last updated: 2017-11-30Bibliographically approved

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Witthöft, Cornelia M.

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