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Experimental Assessment of the Environmental Fate and Effects of Triazoles and Benzotriazole
Publ Hlth Inst Maribor, Slovenia.
Publ Hlth Inst Maribor, Slovenia.
Publ Hlth Inst Maribor, Slovenia.
Univ Insubria, Italy.ORCID iD: 0000-0002-0041-556X
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2013 (English)In: ATLA (Alternatives to Laboratory Animals), ISSN 0261-1929, Vol. 41, no 1, 65-75 p.Article in journal (Refereed) Published
Abstract [en]

The environmental fate and effects of triazoles and benzotriazoles are of concern within the context of chemical regulation. As part of an intelligent testing strategy, experimental tests were performed on endpoints that are relevant for risk assessment. The experimental tests included the assessment of eco-toxicity to an alga, a daphnid and zebrafish embryos, and the assessment of ready biodegradability. Triazole and benzotriazole compounds were selected for testing, based on existing toxicity data for vertebrate and invertebrate species, as well as on the principal component analysis of molecular descriptors aimed at selecting the minimum number of test compounds in order to maximise the chemical domain spanned for both compound classes. The experimental results show that variation in the toxicities of triazoles and benzotriazole across species was relatively minor; in general, the largest factor was approximately 20. The study conducted indicated that triazoles are not readily biodegradable.

Place, publisher, year, edition, pages
2013. Vol. 41, no 1, 65-75 p.
Keyword [en]
algae, aquatic toxicity, benzotriazoles, daphnids, ready biodegradability, triazoles, zebrafish embryos
National Category
Environmental Sciences
Research subject
Natural Science, Environmental Science
Identifiers
URN: urn:nbn:se:lnu:diva-56675ISI: 000330896200026PubMedID: 23614545Scopus ID: 2-s2.0-84877144622OAI: oai:DiVA.org:lnu-56675DiVA: diva2:972680
Available from: 2016-09-22 Created: 2016-09-22 Last updated: 2017-05-08Bibliographically approved

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Papa, EsterSahlin, Ullrika
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CiteExportLink to record
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Citation style
  • apa
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  • de-DE
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  • nn-NB
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  • Other locale
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