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  • 1.
    Aaby, Jacqueline
    et al.
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Ekblom, Jakob
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Hur blev det med hälsan?: En kvalitativ studie om elevers syn på hälsa i ämnet Idrott och hälsa i årskurs nio.2013Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Syftet med denna studie är att undersöka vilken uppfattning elever i årskurs nio har om hälsa. Ämnet Idrott och hälsa bedrivs på olika sätt och syftet med studien är även att få en klarare bild över hur eleverna upplever att de arbetar med hälsa i undervisningen. Genom intervjuer vill vi höra elevernas tankar och erfarenheter om hälsa och vad de skulle vilja lära sig mer om. Vi vill även veta vad de tycker är viktigt för att kunna påverka sin framtida hälsa.

  • 2.
    Aakre, Nina
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Anestesisjuksköterskans uppfattningar av lärande till yrkesprofession: -en fenomenografisk studie.2019Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Anestesisjuksköterskan arbetar i en komplex vårdmiljö med självständigt ansvar för patientens anestesi under operation och förväntas bedöma och hantera komplexa vårdsituationer. Lärande till yrkesprofession sker delvis under utbildningen till specialistsjuksköterska inom anestesi och delvis inom ramen för det yrkeskollektiv som anestesisjuksköterskan arbetar. För att uppnå kompetens som anestesisjuksköterska krävs vissa komponenter i lärandet till yrkesprofession.

    Syfte: Att beskriva anestesisjuksköterskors uppfattningar av lärandet till yrkesprofession.

    Metod: Studien har en kvalitativ design med fenomenografisk forskningsansats.  Anestesisjuksköterskor från en operationsavdelning i sydöstra Sverige har intervjuats kring temat lärande till yrkesprofession. Intervjumaterialet har analyserats enligt fenomenografisk metod.

    Resultat: Fyra beskrivningskategorier som handlade om lärande till yrkesprofession identifierades. Att lära sig utföra anestesisjukvård, att lära sig tänka och agera som anestesisjuksköterska, att lära sig bemöta patienter och att lära sig samarbeta.

    Slutsats: Resultatet visar att för att lära sig vårda en patient i en anestesikontext krävs vissa komponenter. Det är viktigt att vara medveten om dessa komponenter när studenter eller nyanställda skall lära sig yrkesprofessionen. Genom klinisk träning och teoretisk förankring kan anestesisjuksköterskan lära sig vårda komplexa sjukdomstillstånd där patientens säkerhet och integritet bibehålls.

  • 3.
    Aalto, Mervi Anneli
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Vill kunder handla receptfria läkemedel i dagligvaruhandeln?: - En enkätundersökning2008Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpStudent thesis
    Abstract [sv]

    Sammanfattning

    I Sverige har det statliga apoteketsmonopolet ifrågasatts en längre tid och regeringen utreder nu möjligheten att konkurrensutsätta läkemedelsförsäljningen. Det har även föreslagits i den statliga utredningen (SOU 2008:4 del 2) att ett begränsat sortiment av OTC läkemedel (over the counter = receptfria läkemedel) ska få säljas i dagligvaruhandeln utan farmaceutiskt kompetenskrav. Vid korrekt användning och tillgång till rätt rådgivning kan OTC läkemedel vara till en stor hjälp för den enskilde individen vid egenvård och därigenom också bidra till avlastning på sjukvårdens resursers. Vid felanvändning av OTC läkemedel (över/underdosering, fel indikationsområde etc.), kan de istället få motsatt effekt. Syftet med denna enkätstudie var därför att utforska om konsumenter av OTC läkemedel i Sverige önskar få tillgång till dessa läkemedel i t ex livsmedelsbutiker, där de inte har tillgång till personlig farmaceutisk rådgivning, vidare var avsikten att undersöka hur de i dagligvaruhandeln önskade få läkemedelsinformation. I februari 2008 gjordes en enkätstudie i Västervik som inkluderade 48 deltagare varav 29 kvinnor och 19 män. Studien visade att 71 % av deltagarna hade en positiv inställning till att köpa OTC läkemedel i livsmedelsbutiker, 58 % skulle skaffa information genom läkemedelsförpackning och bipacksedel i kombination med att de tidigare använt läkemedlet. Önskan om tillgång till personlig rådgivning på inköpsstället var störst i åldern ≤ 35 år, där 38 % ansåg sig vilja det. Slutsats av studien är att majoriteten vill kunna handla OTC läkemedel i dagligvaruhandeln och information skulle de få främst från läkemedelsförpackning/bipacksedel i kombination med erfarenheter från tidigare användning.

    2008:F5

  • 4.
    Abada, Mariam
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Vilka problem finns det med förfalskade läkemedel?2014Independent thesis Basic level (university diploma), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Världsmarknaden för läkemedlen beräknades år 2011 till 900 miljarder US$ enligt IMS-health. Marknaden för illegala läkemedel uppskattas vara värd mellan 75-200 miljarder dollar. I Sverige uppskattas den illegala läkemedelsmarknaden till motsvarande ≤0,5 %. Straffet för insmuggling av läkemedel till Sverige är böter eller max 2 års fängelse. Tullverket räknar med att man endast hittar 10 % av det som smugglas in. I andra länder kan straffet variera mellan böter (ekonomisk brottslighet i Afrika) till dödsstraff i Kina.

    I Utvecklingsländerna uppskattas 10-30 % av alla läkemedel som säljs vara förfalskade, jmf 1 % I-länderna. l. Förekomsten av förfalskade läkemedel har många allvarliga konsekvenser på människor som exempelvis, utebliven effekt, toxiska reaktioner, förgiftningar, som kan i värsta fall leda till döden. Ett annat alvarligt problem är resistensutveckling, ökad spridning av smittsamammasjukdomar som exempel, tuberkulos och/ eller HIV/AIDS.

    Syftet med detta examensarbete är att besvara frågan: Vilka problem ger den ökande förekomsten av förfalskade läkemedel i samhället. Undersökningen fokuserar på livstidsläkemedel, dvs ett läkemedel en person måste ta resten av sitt liv för behandling av sin kroniska sjukdom.

    För att komma till rätta med de problem, som förfalskade läkemedel, skapar krävs ett mer utvecklat samarbete mellan olika läkemedelsmyndigheter, läkemedelsföretag, internationella polisorganisationer, tull m.fl. Arbetet med att utveckla förpackningar som är svåra att förfalska bör intensifieras. Straffsatser bör kanske ses över. Det är viktigt att öka medvetandet bland allmänheten om risker med att köpa läkemedel utanför apotek (t ex via nätet).

  • 5.
    Abdal Hadi, Jehan
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Hur skiljer sig traditionella från nyare generationer antipsykotika åt vad gäller biverkningen viktökning?2008Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpStudent thesis
    Abstract [sv]

    Antipsykotiska läkemedel är basen för behandling av schizofreni, en psykisk sjukdom som uppträder redan hos unga människor. Symtomen vid schizofreni brukar delas in i positiva symtom (hallucinationer, vanföreställningar, paranoida tankar), negativa symtom (koncentrationssvårigheter, nedsatt språk- och tankeförmåga, minskat intresse för omgivningen, och initiativlöshet), samt kognitiva symtom (minnesproblem, problem med uppmärksamhet och koncentration).

    Antipsykotiska läkemedel delas in i typiska (den äldre generationen) och atypiska (den nyare generationen) antipsykotika. För båda grupperna antipsykotiska läkemedel finns det risk för biverkningar. De vanligaste biverkningarna vid behandling med den äldre generationen antipsykotika är extrapyramidala biverkningar. En biverkning som förefaller mer specifik för de nya atypiska preparaten är viktökning, vilken även kan orsaka utveckling av många allvarliga sjukdomstillstånd.

    Syftet med detta arbete var att jämföra typiska och atypiska antipsykotiska läkemedel med avseende på utveckling av viktökning.

    För att få svar på min frågeställning har en litteraturstudie av fem vetenskapliga artiklar genomförts. De vetenskapliga artiklarna har hittats genom databassökningar i PubMed, medan övriga fakta har hämtats från andra källor.

    Resultatet av de vetenskapliga artiklarna visar att det finns skillnader mellan traditionella och nyare generationer antipsykotika vad gäller tendens att orsaka viktökning. Med några undantag, är flera antipsykotiska läkemedel, som tillhör den nyare generationen, associerade med högre risk för utveckling av viktökning jämfört med den äldre generationen antipsykotika. Viktökning orsakas mest av klozapin, följt av olanzapin och risperidon. Quetiapin orsakar, i likhet med haloperidol, mindre viktökning.

    På grund av detta faktum, forskar man numera kring orsakerna till denna skillnad för att förbättra biverkningsprofilen hos framtida antipsykotika.

    2008:F2

  • 6.
    Abdo, Jasmin
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Tidig insulinbehandling för typ II diabetiker2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Diabetes mellitus är en av de vanligaste endokrina sjukdomarna och de vanligaste formerna är typ I och typ II. Idag har ca 350 000 personer i Sverige diabetes och av dessa har 85-90% diabetes typ II. Typ II diabetes börjar med insulinresistens och så småningom blir det avtagande funktion av β- cellerna vilket leder till nedsatt insulinkänslighet och främsta orsakerna till typ II diabetes är övervikt och fetma. Det finns olika behandlingsrekommendationer för att behandla typ II diabetiker för att minska att sena komplikationer uppstår. Främst genom livsstilsförändringar som kost och fysisk aktivitet, men då dessa inte räcker till kan perorala läkemedel komma i efterhand och om inte det heller ger tillräcklig effekt kan insulinbehandling sättas in. Ca 50 % av typ II diabetiker får insulin efter 10 års sjukdom.

    Syftet med arbetet är att undersöka om det finns en god implikation av att sätta in insulin tidigare än det som redan är rekommenderat.

    Denna litteraturstudie är baserad på artiklar hämtade från databasen PubMed. Sammanlagt har fem randomiserade kontrollerade studier granskats.

    Resultaten visar att en HbA1c-sänkning med ca 1,5 - 2,0 % kan erhållas samt också en bibehållen β- cellfunktion vid insättning av insulin. Insulinbehandlingen bör sättas in så snart HbA1c går över 7,5 % istället för att vänta en viss tid. Den kan sättas in hos behandlingsnaiva personer med framträdande symtom eftersom insulin fortfarande sänker HbA1c och det finns inget som tyder på att insulin inte kan sättas in tidigare än det som är rekommenderat.

    Slutsatsen som dras är att stödja intensiv behandling som gör att HbA1c hålls på en så låg nivå det är möjligt och när målvärden för HbA1c inte kan hållas kan insulin med fördel sättas in hos typ II diabetiker som behandlats med perorala antidiabetika.

  • 7.
    Abdo, Shindar
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Skillnaden mellan ögonen av phenol red thread och Schirmers test2019Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Syfte: Syftet med den här studien var att se om det är någon skillnad mellan ögonen när man utför testen Phenol röd tråd (PRTT) och Schirmers test, och därefter se om det visar någon skillnad mellan de två tester när man diagnostiserar om torra ögon.

    Metod: 30 personer deltog i studien. Innan mätningar fyllde försökpersoner i informationsamtycke och enkäten Ocular Surface Disease Index (OSDI). De undersöktes med PRTT först och därefter utfördes Schirmers test. PRTT utfördes på 20 sekunder, det börjades alltid med höger öga, torka upp nedre fornix med en bomullspinne och till sist mättes den fuktiga delen. Schirmers test utfördes på 5 minuter. Testet består av en pappersremsa som placeras över undre ögonlocket. Resultatet kan läsas av remsan direkt.

    Resultat: Resultatet visar att det inte fanns någon skillnad mellan ögonen och ingen signifikant skillnad mellan olika metoder. Studien visar att det inte fanns samband mellan någon av de två tester och OSDI symtomenkät.

    Slutsats: Slutsatsen av denna studie var att det inte fanns någon skillnad mellan höger respektiv vänster öga när metoder Schirmers test och phenol röd tråd test utfördes. För tydligare resultat av de två tester krävs större urvalsgrupp.

  • 8.
    Abdul Rahim, Ranya
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Kommunikationsproblem på svenska apotek: Förekomst och orsak2019Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    The word communication originates from the Latin word communicare that means to do something in common. When human beings communicate with each other, we share thoughts, emotions, values and actions. The foundation in communication is found within the interpersonal communication, which is the act of communication between two persons. All types of communications include of verbal and nonverbal acts of communication.

    The verbal communication consists of words either in speech or writing, the nonverbal act implies gestures, frequency of the tone and facial expressions.

    Within the pharmaceutical profession, good communication between the pharmacist and the customer is important and can affect the customer’s health and quality of life in both direct as well as indirect ways. In recent years, the pharmacist's role in the pharmacy has drastically changed. Nowadays the care of the customer has gained more significance than before. To improve customer health and quality of life it is important that the pharmacist acts to promote a good relationship with the customer and the foundation for this relationship should be built on good terms of communication.

    The purpose of this study was to study how common it is with communication errors between pharmacist and customer, and to demonstrate probable underlying causes. Secondary questions were, how is the drug advice the pharmacist provides affected by communication errors?

    Collection of data for the study was done with structured observation charts, where the customer and pharmacist were strictly observed. A total of 316 meetings were observed and the data collected referred to prescriptions. In more than one-third of the observed meetings, there were communication errors between the pharmacist and the customer. Communication errors that arose concerned lack of eye contact, language barriers, choice of questions, background noise from colleagues and customers and discussions from generic exchanges. To reduce future communication errors, the pharmacist's actions should be strengthened, such as eye contact, clear follow-up questions and improved feedback.

  • 9.
    Abdulhadi, Nadia M. Noor
    et al.
    Karolinska Inst ; Minist Hlth, Oman.
    Al-Shafaee, Mohammed Ali
    Sultan Qaboos Univ, Oman.
    Wahlström, Rolf
    Karolinska Inst ; Uppsala University.
    Hjelm, Katarina
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Doctors' and nurses' views on patient care for type 2 diabetes: an interview study in primary health care in Oman2013In: Primary Health Care Research and Development, ISSN 1463-4236, E-ISSN 1477-1128, Vol. 14, no 3, p. 258-269Article in journal (Refereed)
    Abstract [en]

    Aim: This study aimed at exploring the experiences of primary health-care providers of their encounters with patients with type 2 diabetes, and their preferences and suggestions for future improvement of diabetes care. Background: Barriers to good diabetes care could be related to problems from health-care providers' side, patients' side or the healthcare system of the country. Treatment of patients with type 2 diabetes has become a huge challenge in Oman, where the prevalence has increased to high levels. Method: Semi-structured interviews were conducted with 26 health-care professionals, 19 doctors and seven nurses, who worked in primary health care in Oman. Qualitative content analysis was applied. Findings: Organizational barriers and barriers related to patients and healthcare providers were identified. These included workload and lack of teamwork approach. Poor patients' management adherence and influence of culture on their attitudes towards illness were identified. From the providers' side, language barriers, providers' frustration and aggressive attitudes towards the patients were reflected. Decreasing the workload, availability of competent teams with diabetes specialist nurses and continuity of care were suggested. Furthermore, changing professional behaviours towards a more patient-centred approach and need for health education to the patients, especially on self-management, were addressed. Appropriate training for health-care providers in communication skills with emphasis on self-care education and individualization of care according to each patient's needs are important for improvement of diabetes care in Oman.

  • 10.
    Abdulhusen, Maria
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Binokulärseende hos elitidrottare: En studie om djupseende, ackommodationsfacilitet och vergensfacilitet2011Independent thesis Basic level (degree of Bachelor), 15 credits / 22,5 HE creditsStudent thesis
    Abstract [sv]

    Syfte: Syftet med denna studie var att ta reda på om elitidrottare som spelar en bollsport har bättre djupseende, bättre förmåga att kunna ändra fokus mellan olika avstånd och mer uthålliga ögonmuskler än personer som inte spelar någon bollsport alls.

    Metod: Mätningarna utfördes på femton innebandyspelare som spelar på elitnivå och femton personer som inte spelar någon bollsport. Medelåldern var 22 år i båda grupperna. Först fick varje försöksperson svara på en enkät, sedan mättes visus upp monokulärt och binokulärt på 3 m med en logMAR visustavla. Efter det mättes djupseendet med Randot stereotest på 40 cm och sedan mättes försökspersonens förmåga att kunna ändra fokus mellan olika avstånd. Detta gjordes på 40 cm med en flipper med styrkorna ±2,00D. Sista mätningen var att få ett mått på hur uthålliga försökspersonens ögonmuskler var, detta gjordes på 40 cm med en flipper av styrkorna 3Δ Bas In/ 12Δ Bas Ut.

    Resultat: Medelvärdet på djupseendet i respektive grupp visade ingen statistisk signifikant skillnad mellan de båda grupperna (p=0,70). Det fanns en signifikant skillnad på medelvärdet mellan de båda grupperna när det gäller förmågan att kunna ändra fokus mellan olika avstånd (p=0,02). Medelvärdet på uthålligheten av ögonmusklerna visade ingen signifikant skillnad mellan de båda grupperna (p=0,08).

    Slutsats: Studien visade att innebandyspelare på elitnivå har bättre förmåga att ändra fokus mellan olika avstånd. Studien visade även att innebandypelare på elitnivå inte har mer uthålliga ögonmuskler eller bättre djupseende än de som inte spelar någon bollsport alls.

  • 11.
    Abdulsalam Muhammednouri, Hevi
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Kan Entresto ersätta ACE-hämmare vid hjärtsvikt och är den behandlingen optimal med avseende på farmakogenetiken?2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Around 200,000–250,000 people suffer from heart failure in Sweden. Heart failure is a condition of impaired heart pumping capacity. The condition results in reduced quality of life, high morbidity and mortality and there have been many attempts to find suitable drug targets to minimize these consequences. Neurohormonal compensatory mechanisms, such as renin–angiotensin–aldosterone system, aim to restore blood pressure to normal levels again but in the long-term it also increases the stress on the heart. The hormone angiotensin II gets activated through this mechanism and is the reason behind the increased stress. Therefore, the hormone has been an important drug target for ACE inhibitors (ACEI) and AT1 blockers (ARB) to prevent antihypertensive effects. The enzyme neprilysin is another drug target whose inhibition is accomplished by using neprilysin inhibitors. Entresto® is a new medication that contains a neprilysin inhibitor and an ARB. The neprilysin inhibitory component, sacubitril, is activated by carboxylesterase 1 (CES1) but mutations in the gene encoding CES1 may cause a non-therapeutic effect. Additionally, patients with wild-type CES1 may risk unacceptable side effects such as rhabdomyolysis and Alzheimer's disease. The objective of this study is to investigate whether replacement of ACE inhibitors with Entresto is optimal in heart failure with regard to pharmacogenetics.

    This study is organized as a literature study in which five scientific articles (I-V) were analyzed and selected from PubMed database and through Linnaeus University's search engine, OneSearch. The studies show that Entresto is superior to enalapril in reducing the risk for cardiovascular death or hospitalization for heart failure. However, the effects of Entresto is dependent on a functioning CES1 gene because mutations like G143E cause a non-therapeutic effect. Enalapril has shown to be independent of such mutations.

    Theoretically, inhibition of neprilysin may cause accumulation of amyloid-β peptides (Aβ), which associates with Alzheimer's disease. Study IV, with the purpose to investigate the effect of Entresto on Aβ isoforms, showed no significant change in Aβ concentrations in cerebrospinal fluid. However, further studies with longer duration were suggested. On the other hand, study V shows that a combination of Entresto and statins increases the plasma concentration of statins. That in turn would increase the risk of a development of rhabdomyolysis. The conclusion is that it is not optimal to replace enalapril with Entresto in heart failure with regard to pharmacogenetics.

  • 12.
    Abiib, Amina
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Probiotika som behandling vid IBS2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: IBS (Irritable Bowel Syndrome) is a functional gastrointestinal disorder, with an unclear etiology and pathophysiology. IBS is a common disorder in the Western population and is characterized by recurrent abdominal pain/ discomfort, bloating, flatulence, diarrhea and/ or constipation. There is currently no cure for IBS, but the interest in probiotics as an option of treatment has recently increased. Probiotics have been defined as live microorganisms that, when administered in adequate amounts, provide a health benefit on the host, and are believed to have a symptomatic effect in IBS. Probiotics have therefore been of interest for the treatment in IBS.

    Purpose: The purpose of this study is to examine whether probiotics have a therapeutic effect and if it could be used as a treatment for IBS.

    Method: Five randomized, double-blind, placebo-controlled studies were reviewed that examined the therapeutic effect of different probiotics in the IBS-patients. Articles were obtained through searches in the medical database PubMed, during the month of February 2016.

    Results: Four of the five studies showed a significant improvement of symptoms especially in abdominal pain/ discomfort. The best results were seen in a study that investigated the probiotic Lactobacillus plantarum 299v. Three of the five studies showed a significant improvement in quality of life (QOL) of the subjects in the study. One of the five studies which examined the effect of Escherichia coli Nissle 1917, there was no significant difference between E.coli (probiotics) and placebo.

    Conclusion: There is reasonable evidence that treatment with certain probiotics might provide improvement in symptoms of abdominal pain/ discomfort, and increase patients quality of life based on the five studies. Further studies are required to determine the most effective probiotic, dose and duration of IBS-treatment.

  • 13.
    Abrahamsson, Daria
    et al.
    Linnaeus University, Faculty of Health, Social Work and Behavioural Sciences, School of Health and Caring Sciences.
    Miller, Sofi
    Linnaeus University, Faculty of Health, Social Work and Behavioural Sciences, School of Health and Caring Sciences.
    MRSA – EN FÖLJETONG UTAN SLUT: Effekter av olika åtgärder i smittskyddsarbete mot MRSA 2010Independent thesis Basic level (degree of Bachelor), 15 credits / 22,5 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Multiresistenta bakterier, däribland MRSA, är idag ett globalt samhällsproblem. Infektioner förorsakade av MRSA skapar ett onödigt lidande för patienter med utdragen vårdtid som i värsta fall kan resultera i ökad dödlighet. Enligt Smittskyddsinstitutet (2010) drabbades 1479 patienter förra året i Sverige. Med få verksamma antibiotika måste andra åtgärder tillämpas, så som basala hygienrutiner, screening, isoleringsvård och utökad städning av sjukhusmiljön. Det är dock viktigt att utvärdera åtgärdernas effekter för att kunna utföra smittskyddsarbete på bästa möjliga sätt.

    Syfte: Syftet var att undersöka effekterna av olika åtgärder i smittskyddsarbetet mot MRSA.

    Metod: Litteraturstudie med kvantitativ ansats baserad på tio vetenskapliga original artiklar. Analysen gjordes enligt Forsberg och Wengströms (2008) riktlinjer för meta-analys.

    Resultat: Studien visar att MRSA förekommer i kliniska miljöer samt förutom hos patienten även hos vårdpersonal. Förebyggande åtgärder som bland annat noggrann städning, basala hygienrutiner och screening hade varierande effekt och reducerade MRSA- förekomsten bäst i kombination. I vissa fall kunde brister i vårdpersonalens följsamhet (compliance) av hygienrutiner ses.

    Slutsats: För att reducera MRSA- förekomst och spridning är det viktigt att implementera de åtgärder som finns idag och som visat sig har effekt. För att genomföra detta krävs det att vårdpersonalens följsamhet blir bättre.

     

     

  • 14.
    Abrahamsson Emelie, Salomonsson Elsa
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Sjuksköterskans upplevelse och föreställningar av mötet med våldsutsatta kvinnor2014Independent thesis Basic level (university diploma), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Kvinnor som utsatts för våld i nära relarion kommer mer frekvent i kontakt med sjukvården än andra kvinnor. Flera kvinnor som söker vård för sina skador identifieras aldrig som offer för våld i nära relation. Detta beror på att flera sjuksköterskor saknar utbildning i att identifiera att våld förekommer. Det finns en osäkerhet hos sjuksköterskan i mötet med våldsutsatta kvinnor som gör att mötet med vården av kvinnan påverkas.

    Syfte: Syftet var att belysa sjuksköterskans upplevelse och föreställningar av mötet med våldsutsatta kvinnor inom hälso-och sjukvården.

    Metod: En systematisk litteraturstudie där sex kvalitativa artiklar och två kvantitativa artiklar har granskats, analyserats och kategoriserats.

    Resultat: Det fanns en tydlig emotionell påverkan hos sjuksköterskor under och efter mötet med våldsutsatta kvinnor. En påverkan som ibland var så stor att det påverkade deras privatliv. Det visade sig även finnas ett stort utbildningsbehov att förbättra vården för våldsutsatta kvinnor och få sjuksköterskor att känna sig tryggare i rollen som vårdare för dessa kvinnor.

    Slutsats: Det visade sig finnas ett ökat utbildningsbehov för sjuksköterskor i hur de ska bemöta och vårda kvinnor som utsatts för våld i nära relationer. Det fanns även ett behov av att bearbeta de känslor sjuksköterskan upplevde i mötet med kvinnorna. 

  • 15.
    Abrahamsson, Janna
    et al.
    Linnaeus University, Faculty of Health, Social Work and Behavioural Sciences, School of Health and Caring Sciences.
    Holmgren, Maria
    Linnaeus University, Faculty of Health, Social Work and Behavioural Sciences, School of Health and Caring Sciences.
    En strimma hopp i mörkret: En litteraturstudie om lidande och välbefinnande i samband med depression2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 16.
    Abrahim, Mehammedsrage
    Linnaeus University, Faculty of Health, Social Work and Behavioural Sciences, School of Health and Caring Sciences.
    SELF-CARE IN TYPE 2 DIABETES: A Systematic Literature Review on Factors Contributing to Self-Care among Type 2Diabetes Mellitus Patients.2011Independent thesis Advanced level (degree of Master (Two Years)), 80 credits / 120 HE creditsStudent thesis
    Abstract [en]

    Background: Self-care is a multi-dimensional concept and has different definitions. Amongthe definitions, Orem’s definition of self-care is more consistent. Orem (1995) argues that,self-care is a personal activity to take care and maintain of own self health and illness andprevention of disease related complications.

    Aim: The aim of the paper was to investigate the factors that contribute to self-care behavioramong patients with Type 2 DM as argued in the literature.

    Method: data was collected from the following electronic databases: CINAHL, PubMed,LibHub, SweMed and Google Scholar-to find full texts. Data was analyzed through CriticalAppraisal Skill Programme. To ensure validity and reliability the author were blinded toreduce study bias and articles were selected according their quality.

    Result: 31 relevant studies were included in the review, among the major findings of the studywere; Age, Social support/network, high income level, high educational attainment and longType 2 DM diagnosis history had a positive predictor in Type 2 DM patients self-carecontributing factors.

    Conclusion: To improve a Type 2 DM patients self-care activities the present study concludedthat Demographic, Socio-Economic and Social support factors are among the positivecontributors in patients of Type 2 DM successful Self-Care activities.

    Key words; Blood glucose self-monitoring, self-administration, Self-care, self-medication,Type 2 Diabetes.

  • 17.
    Adams, Marc A.
    et al.
    Arizona State University, USA.
    Ding, Ding
    University of Sydney, Australia.
    Sallis, James F.
    University of California, USA.
    Bowles, Heather R.
    National Institutes of Health, USA.
    Ainsworth, Barbara E.
    Arizona State University, USA.
    Bergman, Patrick
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Bull, Fiona C.
    The University of Western Australia, Australia.
    Carr, Harriette
    Ministry of Health, New Zealand.
    Craig, Cora L.
    School of Public Health, Canada.
    De Bourdeaudhuij, Ilse
    Ghent University, Belgium.
    Fernando Gomez, Luis
    Hagstromer, Maria
    Klasson-Heggebo, Lena
    Inoue, Shigeru
    Lefevre, Johan
    Macfarlane, Duncan J.
    Matsudo, Sandra
    Matsudo, Victor
    McLean, Grant
    Murase, Norio
    Sjostrom, Michael
    Tomten, Heidi
    Volbekiene, Vida
    Bauman, Adrian
    Patterns of neighborhood environment attributes related to physical activity across 11 countries: a latent class analysis2013In: International Journal of Behavioral Nutrition and Physical Activity, ISSN 1479-5868, E-ISSN 1479-5868, Vol. 10, article id 34Article in journal (Refereed)
    Abstract [en]

    Background: Neighborhood environment studies of physical activity (PA) have been mainly single-country focused. The International Prevalence Study (IPS) presented a rare opportunity to examine neighborhood features across countries. The purpose of this analysis was to: 1) detect international neighborhood typologies based on participants' response patterns to an environment survey and 2) to estimate associations between neighborhood environment patterns and PA. Methods: A Latent Class Analysis (LCA) was conducted on pooled IPS adults (N=11,541) aged 18 to 64 years old (mean=37.5 +/- 12.8 yrs; 55.6% women) from 11 countries including Belgium, Brazil, Canada, Colombia, Hong Kong, Japan, Lithuania, New Zealand, Norway, Sweden, and the U. S. This subset used the Physical Activity Neighborhood Environment Survey (PANES) that briefly assessed 7 attributes within 10-15 minutes walk of participants' residences, including residential density, access to shops/services, recreational facilities, public transit facilities, presence of sidewalks and bike paths, and personal safety. LCA derived meaningful subgroups from participants' response patterns to PANES items, and participants were assigned to neighborhood types. The validated short-form International Physical Activity Questionnaire (IPAQ) measured likelihood of meeting the 150 minutes/week PA guideline. To validate derived classes, meeting the guideline either by walking or total PA was regressed on neighborhood types using a weighted generalized linear regression model, adjusting for gender, age and country. Results: A 5-subgroup solution fitted the dataset and was interpretable. Neighborhood types were labeled, "Overall Activity Supportive (52% of sample)", "High Walkable and Unsafe with Few Recreation Facilities (16%)", "Safe with Active Transport Facilities (12%)", "Transit and Shops Dense with Few Amenities (15%)", and "Safe but Activity Unsupportive (5%)". Country representation differed by type (e. g., U. S. disproportionally represented "Safe but Activity Unsupportive"). Compared to the Safe but Activity Unsupportive, two types showed greater odds of meeting PA guideline for walking outcome (High Walkable and Unsafe with Few Recreation Facilities, OR=2.26 (95% CI 1.18-4.31); Overall Activity Supportive, OR=1.90 (95% CI 1.13-3.21). Significant but smaller odds ratios were also found for total PA. Conclusions: Meaningful neighborhood patterns generalized across countries and explained practical differences in PA. These observational results support WHO/UN recommendations for programs and policies targeted to improve features of the neighborhood environment for PA.

  • 18.
    Adel Ali, Sura
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Kan manuell analys av Csv-EPK ersättas med automatiserad analys på Sysmex XN-1000?2016Independent thesis Basic level (degree of Bachelor), 180 HE creditsStudent thesis
    Abstract [en]

    Determination of erythrocyte count in cerebrospinal fluid (CSF-EPC) is used to exclude various intracranial hemorrhage, especially subarachnoid hemorrhage (SAH). SAH means a bleeding between the pia mater and arachnoidea which occurs due to rupture of an aneurysm in the subarachnoid space. Manual counting of erythrocytes in the cerebrospinal fluid with Bürkers chamber and microscopy has been the gold standard for the past decades, but the manual method is time consuming and requires great experience. The purpose of this study was to evaluate if manual analysis of  CSF-EPC with counting chamber, and light microscopy can be replaced by automated analysis of CSF-EPC with Hematology Analyzer XN-1000 (Sysmex). Fortyeight cerebrospinal fluid samples with various concentrations of erythrocytes ware prepared by diluting known concentration of erythrocytes in cell-free CSF. Prepared CSF-samples with added erythrocytes were analyzed first on the XN-1000. Thereafter, manual counting of erythrocytes was performed using Bürkers counting chamber. A linear regression was established to describe the correlation between the automated analysis of the CSF-EPC and manual analysis of the CSF-EPC. Imprecision in the analysis of the CSF-EPC on the XN-1000 (Sysmex) was assessed by within-run imprecision. A very good correlation (r = 0.999) was found between the XN-1000 and manual counting. For results in the lower range, 100 - 5000 (106/L), correlation was also good (r = 0.997). The coefficient of variation was 19,8 % at CSF-EPC of 370 x 106/L and 3.1 % at CSF-EPC of 25 950 x 106/L. The sensitivity for analysis of CSF-EPC on XN-1000 was 370 x 106/L. The conclusion is that the analysis of Csv-EPC on XN-1000 can be used for clinical diagnostics of CSF- samples. However, it should be noted that XN-1000 has poor sensitivity for low CSF-EPC values < 370 x 106/L. To ensure high diagnostic quality even in CSF-samples with low erythrocyte counts are recommended a reference limit of < 500 x 106/L as a practical cut off for supplemental microscopic counting in routine healthcare laboratories.

     

     

     

  • 19.
    Adetayo-odepidan, Mojeed
    Linnaeus University, Faculty of Technology, Department of Informatics.
    Electronic Health Record Systems: A study of privacy in the region Kronoberg of Sweden2016Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    This study gives a brief description of paper-based record and the adoption of ICT, which brought the introduction of Electronic Health Record System (EHRS) in Sweden, the challenges facing EHR in the health care sector around the world and what immigrants and newcomers who just arrived in Sweden knows about the privacy,  rights and the policies that protect their privacy and data system, these could cause them not having enough confidence in electronic health record system, they could also be worried about their information been exposed or disclosed by their healthcare providers, this call for the confidentiality, security and privacy of EHR System. The aim of this study is to explore immigrants and newcomers as users of electronic health record system by setting interview questions and focus group to help the researcher to understand their knowledge of what they know about the privacy of EHRS and what they know about the policies health care providers follow to protect patient’s privacy and data. It is very important for them to know their rights and the rights that protect their privacy and data from been shared or disclosed.

     

    The study also talked about the existing implications facing EHRs, comparison of both systems was shown in table 1 of this study. The necessity for a proper protection of patient data was discussed and recommendation was made towards having a great and a working electronic health record system. 

  • 20.
    Adevåg Guagliano, Sofia
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Nilsson, Johan
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Patienters upplevelse av delaktighet i vård i livets slut: En systematisk litteraturstudie2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Palliative care is performed throughout the continuum of care, from home care to specialized care in an institution. Palliative care is buildt on a holistic approach that is secured through patient-centered care where the patient's participation is central.

    Objective: Highlighting adult patients' experiences of participation when they are cared for in late stage palliative care.

    Method: The study is a systematic literature review mainly based on the methodology described by Forsberg and Wengström (2013).

    Results: The theme opportunities and obstacles in the experience of their participation emerged, with four categories below: the management of their disease situation, overwhelming new living situations, be seen as an individual and not to be seen as an                                    individual. It was discovered that patients in the late stage palliative phase found opportunities to participate in their care by gathering knowledge about their disease and their future. This knowledge created understanding, giving them the tools to manage and participate in their care. An obstacle to patients’ participation appeared to be when the patients experienced neglect by health professionals.

    Conclusion: Adult patients' experiences of participation when they are cared for in late stage palliative care cannot be described as a single phenomenon, but needs to be described by an integrated approach of the patient. The unique patient forms a dynamic whole, and needs to be treated as the unique individual he/she is.

  • 21.
    Adler, Anna
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Är det säkert att byta från originalläkemedlet för inflixmab, Remicade®, till CT-P13 och är CT-P13 ekvivalent med Remicade® med avseende på effekt, säkerhet, immunogenicitet och farmakokinetik?2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Biologic drugs are effective against numerous diseases but they are very expensive. The European Medicines Agency approved sales of biosimilars in 2006. Biosimilars are copies of already approved biologic drugs, but they are not considered to be exact copies like generic drugs are. Only living organisms can produce substances with the complexity of biologic drugs. Differences in pH, enviroment, and the purification process during the production of biologic drugs can affect the structure of the final product. Differences in the production processes can affect properties like the glycosylation pattern of the molecules which in turn can influence the effect of the drug. This is the reason biosimilars are not considered as exact copies of the original drug. The patent for Remicade® a TNF inhibitor expired in 2015 which led to the introduction of the first biosimilar for monoclonal antibodies (CT-P13) on the European market. The aim of this study was to investigate the efficacy, safety profile, immunogenicity and pharmacokinetics equivalence between CT-P13 and the original drug for infliximab, Remicade®. And to investigate if it was safe to switch from Remicade to CT-P13.

     

    The articles for the study were collected from PubMed, a medical and bioscientific database, and five studies were chosen for further analysis. The articles were not limited to a specific indication for infliximab, so the studies included patients with rhematoid arthritis (RA), ankylosing spondylitis (AS) and inflammatory bowel disease (IBD). The short-term equivalence between Remicade® and CT-P13 was analysed in the studies but more studies including long-term equivalence are needed. Based on the primary endpoints in the studies it seems to be safe to switch from Remicade® to CT-P13 and short-term equivalence seems to exist between CT-P13 and Remicade® considering the efficacy, safety profile, immunogenicity and pharmacokinetics equivalence in patients with RA, AS and IBD.

  • 22.
    Adolfsson, Johanna
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Neureuther, Emma
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Se mig för den jag är - Jag är också en människa: Hur självskadebeteende påverkar kvinnans livsvärld - en studie gjord på bloggar2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakrund:I Sverige har självskadebeteende hos kvinnor i åldrarna 15-24 år ökat avsevärt sedan 90-talet fram till 2007. Självskadebeteende definieras med att medvetet skada sin egen kropp. Det kan upplevas som ångestlindrande men många har också i avsikt att ta sitt eget liv. Syfte: Syftet är att belysa unga kvinnors upplevelser av att leva med självskadebeteende. Metod: Studien har gjorts med en kvalitativ ansats med ett livsvärldsperspektiv och baseras på fem bloggar. Bloggarna analyserades med hjälp av Graneheim och Lundman innehållsanalys (2004). Resultat: Ur resultatet framkom fem kategorier som beskriver de unga kvinnornas känslor av att leva med ett självskadebeteende. De fem kategorierna är att uppleva ångest, trygghet, uppgivenhet och smärta, samt att i efterhand begrunda sin situation. Slutsats: Ur reslutatet framkom att de vanligaste förekommande känslorna i samband med självskadebeteende är ångest, smärta, ensamhet och uppgivenhet. Kvinnorna beskriver att de vill göra den psykiska smärtan fysisk. Självskadebeteende kan även ses som ett beroende. Som sjuksköterska är det viktigt att ta del av kvinnans livsvärld för att kunna möte henne på bästa sätt.

  • 23.
    Adolfsson, Matilda
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Anthelmintika mot hästens inälvsparasiter: en studie av effekt, resistensförekomst och försäljning2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 24. Adolfsson, Peter
    et al.
    Roos, Harald
    Lunds universitet.
    Östenberg, Anna
    Lunds universitet.
    Speciella aspekter på damfotboll1998In: Fotbollsmedicin, Solna: Svenska fotbollförbundet , 1998, 1, p. 435-450Chapter in book (Other academic)
  • 25.
    Adolfsson, Sophie
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Wernholm, Emma
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Mastektomins påverkan på kvinnors livskvalitet: En systematisk litteraturstudie2017Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: I Sverige drabbas ungefär 20 kvinnor av bröstcancer varje dag och nästan hälften har genomgått en mastektomi. En av sjuksköterskans uppgifter är att ge stöd för att förbättra kvinnans livskvalitet, då kvinnan ska uppleva ett gott liv med harmoni i sig själv och sin omgivning.Studien förankrades i Katie Erikssons lidandeteori.

     

    Syfte: Syftet var att beskriva hur en mastektomi till följd av bröstcancer kan påverka kvinnors livskvalitet.

     

    Metod: En systematisk litteraturstudie med induktiv ansats har använts. Datainsamlingen resulterade i 17 artiklar som sedan kvalitetsgranskades. Totalt ingick 14 artiklar. En manifest innehållsanalys genomfördes.

     

    Resultat: Resultatet utgörs av fyra huvudkategorier: Operationens fysiska och psykiska konsekvenser, Förändrade relationer, Inverkan av det kosmetiska resultatet med tre tillhörande underkategorier samt Acceptansens betydelse. En mastektomi leder till både fysiska och psykiska påfrestningar som påverkar livskvaliteten. Förmågan att skapa relationer försämrades. Många kvinnor upplevde bröstförlusten som påfrestande genom att kroppsuppfattningen, kvinnligheten och sexualiteten påverkades negativt. Äldre kvinnor accepterade förlusten lättare.

     

    Slutsats: Kvinnor som genomgått en mastektomi upplevde sämre livskvalitet där förlorandet av bröstet spelar stor roll. De drabbas emotionellt och förlusten har betydelse för livskvaliteten. Resultatet kan ge en ökad förståelse för sjuksköterskor som i sin tur kan vara ett stöd för att lindra lidande.

  • 26.
    Adolfsson, Zandra
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Isomettä, Frida
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Kvinnors erfarenheter av att leva med symtomgivande endometrios: En systematisk litteraturstudie2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    SAMMANFATTNING:

    Bakgrund: Endometrios är en sjukdom som drabbar 10% av livmoderbärande kvinnor över hela världen. Att lida av endometrios kan innebära symtom som kraftig bäckensmärta, kraftiga blödningar, dyspareuni och infertilitet.

    Syfte: Beskriva kvinnors erfarenheter av att leva med symtomgivande endometrios.

    Metod: En systematisk litteraturstudie har använts. 10 artiklar valdes ut, kvalitetsgranskades och analyserades.

    Resultat: I resultatet framkom olika kategorier som beskriver kvinnornas olika erfarenheter av att leva med endometrios. Det handlade om erfarenheter av fysiska symtom, erfarenheter av möten i vården, emotionella erfarenheter och erfarenheter av sociala relationer.

    Slutsats: Studien visade att endometrios påverkade kvinnorna fysiskt, psykiskt och socialt. Kvinnornas liv påverkades av sjukdomen på många sätt och gjorde att de kände sig begränsade i vardagen. Den långa tiden för att få en diagnos fastställd orsakade vårdlidande. Kvinnorna möttes av misstro från vården där symtomen avfärdades som kvinnoproblem. Kvinnornas känslor växlade under sjukdomstiden, allt mellan hopp och förtvivlan inför framtiden.

  • 27.
    Adolfsson, Zandra
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Karlsson, Michaela
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Barnvaccinationer: BHV-sjuksköterskans kommunikation och information till föräldrar. 2018Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: The childhood vaccination program is the most successful medical response to public health. Despite this, there have always been negative voices about vaccination. Information about childhood vaccinations is spread quickly and easily through media and information channels, such as Facebook and YouTube. This information is not always critically reviewed and suspected sideeffects may then be overestimated. Evidence shows that there is a variety of reasons why some parents have doubt about childhood vaccination. Child Health nurse's task is to meet all parents with respect and give correct information so the parents have a decision basis for vaccination.

    A lack of communication between the Child Health nurse and the parents can contribute to increased concern, which may lead to the parents choosing to abstain from vaccination.

    Aim: The aim was to describe Child Health nurse's experiences of communicating with parents before childhood vaccinations.

    Method: Semi-structured interviews with nine Child Health nurses. The study has been analyzed using a qualitative content analysis.

    Results: The result showed that all participants in the study felt that most parents had a positive attitude towards childhood vaccination. The study showed that the Child Health nurses felt that they provided a good and distinct information to the parents. At the same time, participants believed that the dissemination of information could be improved. It showed that there are differences in when Child Health nurses present information to the parents. The participants in the study felt safe in the meeting with parents and about communication of information prior to vaccination.

    Conclusion: The study showed that Child Health nurses felt secure about communication, both with information before vaccination and in meeting hesitent parents. Child Health nurses described that they had good and distinct information within the organization.

  • 28.
    Adriansson, Anna-Karin
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Snäll, Carina
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Digitaliserad vård i hemmet: En kvalitativ studie av hur äldre patienter med hjärtsvikt och deras anhöriga upplever självmonitorering med ny digital teknik2019Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Background: Sweden has one of the highest proportions of older people in the world. More people live longer with chronic diseases, which increases the demand for care. The proportion of people with heart failure is increasing. Digital technology can become an important link between patient, relative and healthcare. Increased use of digital technology in healthcare can help patients with chronic illness and lead to a better quality of life. Self-monitoring in the home provides a quick indication of deterioration and leads to less emergency visits and admissions as well as reduced healthcare costs.

    Aim: The aim was to describe the experience of self-monitoring in the home based on the elderly patient with heart failure and the relative's perspective.

    Method: A qualitative study with inductive design was chosen to answer the study's purpose and problem area. Data was obtained through semi-structured interviews, and analysed using qualitative analysis according to Malterud's systematic text condensation.

    Results: Seven elderly patients with heart failure and six relatives participated in the study.  Participants self-monitored in the home using a mobile device. The analysis resulted in three categories. Aspects of security and insecurity related to self-monitoring, self-monitoring provides support for self-care and self-monitoring a support to become a partner in care but also a responsibility.

    Conclusion: Health care is facing major challenges with an increasing ageing population where more people live longer with chronic diseases. The patient needs to become more involved and need to take greater responsibility for their own care. The results of the study indicate that elderly patients with heart failure and their relatives through self-monitoring in the home experience security, are described to gain an increased knowledge of their disease and treatment and take greater responsibility for their health by performing advanced self-care at home.

  • 29.
    Aeinehband, Shahin
    et al.
    Karolinska Institutet.
    Lindblom, Rickard P. F.
    Karolinska Institutet.
    Al Nimer, Faiez
    Karolinska Institutet.
    Vijayaraghavan, Swetha
    Karolinska Institutet.
    Sandholm, Kerstin
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Khademi, Mohsen
    Karolinska Institutet.
    Olsson, Tomas
    Karolinska Institutet.
    Nilsson, Bo
    Uppsala University.
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences. Uppsala University.
    Darreh-Shori, Taher
    Karolinska Institutet.
    Piehl, Fredrik
    Karolinska Institutet.
    Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis2015In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 10, no 4, article id e0122048Article in journal (Refereed)
    Abstract [en]

    Dysregulation of the complement system is evident in many CNS diseases but mechanisms regulating complement activation in the CNS remain unclear. In a recent large rat genomewide expression profiling and linkage analysis we found co-regulation of complement C3 immediately downstream of butyrylcholinesterase (BuChE), an enzyme hydrolyzing acetylcholine (ACh), a classical neurotransmitter with immunoregulatory effects. We here determined levels of neurofilament-light (NFL), a marker for ongoing nerve injury, C3 and activity of the two main ACh hydrolyzing enzymes, acetylcholinesterase (AChE) and BuChE, in cerebrospinal fluid (CSF) from patients with MS (n = 48) and non-inflammatory controls (n = 18). C3 levels were elevated in MS patients compared to controls and correlated both to disability and NFL. C3 levels were not induced by relapses, but were increased in patients with >= 9 cerebral lesions on magnetic resonance imaging and in patients with progressive disease. BuChE activity did not differ at the group level, but was correlated to both C3 and NFL levels in individual samples. In conclusion, we show that CSF C3 correlates both to a marker for ongoing nerve injury and degree of disease disability. Moreover, our results also suggest a potential link between intrathecal cholinergic activity and complement activation. These results motivate further efforts directed at elucidating the regulation and effector functions of the complement system in MS, and its relation to cholinergic tone.

  • 30.
    Agerbjer, Emma
    et al.
    Växjö University, Faculty of Humanities and Social Sciences, School of Health Sciences and Social Work.
    Karlsson, Marie
    Växjö University, Faculty of Humanities and Social Sciences, School of Health Sciences and Social Work.
    SJUKSKÖTERSKORS INSTÄLLNING OCH ANVÄNDANDE AV FYSISK AKTIVITET PÅ RECEPT (FaR®): en enkätstudie2009Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Fysisk aktivitet är all kroppsrörelse som resulterar i ökad energiförbrukning. Genom att vara fysisk aktiv så minskar risken att drabbas av flera sjukdomar. Balans och muskelstyrka förbättras och risk för benskörhet minskar. Fysisk aktivitet kan användas både i förebyggande syfte och som behandling av sjukdom. Sedan 2001 har fysisk aktivitet kunnat förskrivas på recept (FaR®). FaR® innebär att en läkare, sjuksköterska, sjukgymnast eller annan legitimerad vårdpersonal kan ordinera fysisk aktivitet på ett liknande sätt som läkemedel.

    Syfte: Syftet med studien var att kartlägga inställning till och användande av fysisk aktivitet på recept (FaR®) hos sjuksköterskor i primärsjukvården inom Växjö kommun.

    Metod: Metoden som användes var en kvantitativ enkätundersökning som genomfördes på sjuksköterskor på elva vårdcentraler inom Växjö kommun. Svarsfrekvensen var 73 %.

    Resultat: De flesta sjuksköterskorna i studien diskuterade ofta fysisk aktivitet med sina patienter. Inställningen till FaR® var övervägande positiv, en knapp fjärdedel hade förskrivit FaR®.

    Slutsatser: Sjuksköterskor är mycket eller ganska positiva till att ordinera FaR® i förebyggande syfte och merparten av dem är positiva till att ordinera FaR® i behandlande syfte. En trolig slutsats är att FaR® kommer att användas i större utsträckning i framtiden under förutsättning att tillräcklig utbildning och uppföljning görs.

  • 31.
    Ageton, Jenny
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Sjuksköterskors upplevelser av att, som telefonrådgivare vid 1177, samtala med vuxna patienter som väntar på samtalsstöd i primärvården.2018Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Psykisk ohälsa är den vanligaste orsaken till sjukskrivning i Sverige. Uppskattningsvis lider mellan fem och tio procent av befolkningen av en så allvarlig psykisk ohälsa att den kräver psykiatrisk vård. Att få professionell hjälp i form av samtalsstöd kan ge patienten en trygghet och kan även hjälpa patienten att förstå sin situation på ett bättre sätt. En del patienter som väntar samtalsstöd i primärvården ringer 1177 och berättar att de tycker det tar lång tid att få hjälp till samtalsstöd.

    Syfte: Studiens övergripande syfte är att belysa sjuksköterskors upplevelser av att, i rollen som telefonrådgivare vid 1177, samtala med vuxna patienter som väntar på samtalsstöd i primärvården.

    Metod: Studien genomfördes med en kvalitativ metod med semistrukturerade intervjuer, där nio sjuksköterskor på 1177 Vårdguiden deltog. Alla deltagare var kvinnor. Analysen genomfördes med en kvalitativ innehållsanalys.

    Resultat: Sjuksköterskornas berättelser om telefonsamtal med patienter som väntar samtalsstöd i primärvården belyser; Sjuksköterskornas tankar och känslor, vilka möjligheter finns för att hjälpa patienterna? Hur hanterar och bearbetar sjuksköterskorna svåra samtal och vilken kompetens och resurser har sjuksköterskorna?

    Slutsats: Det är mycket som krävs för att ett samtal ska kännas bra för sjuksköterskan på 1177 vårdguiden. Studien ger en bild av de upplevelser sjuksköterskorna på 1177 Vårdguiden har av att samtala med patienter som väntar samtalsstöd i primärvården. Vad kan behöva utvecklas för att sjuksköterskorna ska hantera dessa samtal?

  • 32.
    Agevall, Lena
    et al.
    Växjö University, Faculty of Humanities and Social Sciences, School of Social Sciences. Statsvetenskap.
    Jonnergård, Karin
    Växjö University, Faculty of Humanities and Social Sciences, School of Management and Economics. Ekonomistyrning.
    Management by documents - a risk of de-professionalizing?2007In: In tension between Organization and Profession: Professionals in Nordic Public Service, Nordic Academic Presss, Lund , 2007, p. 33-56Chapter in book (Other (popular science, discussion, etc.))
    Abstract [en]

    If we have to document our professional action, will we then only perform the actions that we are supposed to document? This question reflects the content of this chapter. The chapter includes a frame of reference for studying control of professionals in organizations and illustration on different types of professional controls.

  • 33. Agewall, Stefan
    et al.
    Rydén, Lars
    Perk, Joep
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Rosengren, Annika
    Boman, Kurt
    Hellénius, Mai-Lis
    Ros, Inger
    Efterlyses: politik mot hjärtinfarkt2013In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 110, no 13-14, p. 664-664Article in journal (Other (popular science, discussion, etc.))
    Abstract [sv]

    Medicinen kommer inte så mycket längre när det gäller att minska dödligheten i hjärt–kärlsjukdomar. Framtidens utmaning ligger i att förhindra att människor alls insjuknar i hjärtinfarkt. Författarna efterlyser politiska åtgärder som gör de hälsosamma valen billiga och attraktiva.

  • 34.
    Ahl, Johannes
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Karlsmo, Martin
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    SJUKSKÖTERSKANS STRESS RELATERAD TILL ARBETSBELASTNING: En enkätsstudie2017Independent thesis Basic level (degree of Bachelor), 15 credits / 22,5 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Negativ arbetsrelaterad stress är ett ständigt problem i flera samhällssektorer, även så i stor utsträckning inom vårdsektorn. Forskning visar att arbetsrelaterad stress inom vården kan utlösas av flera olika faktorer, bland annat en för hög arbetsbelastning. Långvarig negativ stress kan orsaka utmattningssymtom och utbrändhet.

    Syfte: Syftet med studien var att undersöka stress relaterad till arbetsbelastningen hos allmänsjuksköterskor som arbetar på sjukhusavdelningar.

    Metod: En kvantitativ enkätstudie utfördes på fyra sjukhusavdelningar på ett sjukhus i Södra Sverige. Instrumentet Maslach Burnout Inventory- HSS användes för att mäta respondenternas stress. Resultatet redovisades och analyserades med deskriptiv statistik, regressionsanalys och Spearmans rangkorrelationskoefficient.

    Resultat: Resultatet visar att det hos allmänsjuksköterskor finns ett samband mellan arbetsbelastning och stress. Samband uppmättes mellan antal övertidstimmar och utbrändhetsfaktorn ”Otillräcklighet” (p < 0,05), samt mellan känslan av att vara överarbetad och utbrändhetsfaktorn ”Emotionell utmattning” (p < 0,01).  Resultatet visar också att bakgrundsfaktorer som kan kopplas  till privatlivet spelar en mindre roll för sjuksköterskornas upplevda arbetsstress och att det huvudsakligen är arbetsrelaterade faktorer som påverkar upplevelsen av stress.

    Slutsats: Den undersökta populationen lider av stressfaktorer kopplade till arbetsbelastning och låg arbetstillfredsställelse och majoriteten av den undersökta populationen löper en risk att drabbas av utbrändhet. För att bibehålla god vårdkvalité, eller förbättra den ytterligare, bör åtgärder för att sänka arbetsbelastningen och öka arbetstillfredställelsen ses över.

  • 35.
    Ahlander, Britt-Marie
    et al.
    Ryhov County Hospital.
    Årestedt, Kristofer
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences. Linköping University.
    Engvall, Jan
    Linköping University.
    Maret, Eva
    Karolinska Univ Hosp ; Karolinska Institutet.
    Ericsson, Elisabeth
    Örebro university.
    Development and validation of a questionnaire evaluating patient anxiety during Magnetic Resonance Imaging: the Magnetic Resonance Imaging-Anxiety Questionnaire (MRI-AQ)2016In: Journal of Advanced Nursing, ISSN 0309-2402, E-ISSN 1365-2648, Vol. 72, no 6, p. 1368-1380Article in journal (Refereed)
    Abstract [en]

    Aim. To develop and validate a new instrument measuring patient anxiety during Magnetic Resonance Imaging examinations, Magnetic Resonance Imaging-Anxiety Questionnaire. Background. Questionnaires measuring patients' anxiety during Magnetic Resonance Imaging examinations have been the same as used in a wide range of conditions. To learn about patients' experience during examination and to evaluate interventions, a specific questionnaire measuring patient anxiety during Magnetic Resonance Imaging is needed. Design. Psychometric cross-sectional study with test-retest design. Methods. A new questionnaire, Magnetic Resonance Imaging-Anxiety Questionnaire, was designed from patient expressions of anxiety in Magnetic Resonance Imaging-scanners. The sample was recruited between October 2012-October 2014. Factor structure was evaluated with exploratory factor analysis and internal consistency with Cronbach's alpha. Criterion-related validity, known-group validity and test-retest was calculated. Results. Patients referred for Magnetic Resonance Imaging of either the spine or the heart, were invited to participate. The development and validation of Magnetic Resonance Imaging-Anxiety Questionnaire resulted in 15 items consisting of two factors. Cronbach's alpha was found to be high. Magnetic Resonance Imaging-Anxiety Questionnaire correlated higher with instruments measuring anxiety than with depression scales. Known-group validity demonstrated a higher level of anxiety for patients undergoing Magnetic Resonance Imaging scan of the heart than for those examining the spine. Test-retest reliability demonstrated acceptable level for the scale. Conclusion. Magnetic Resonance Imaging-Anxiety Questionnaire bridges a gap among existing questionnaires, making it a simple and useful tool for measuring patient anxiety during Magnetic Resonance Imaging examinations.

  • 36.
    Ahlberg, Christopher
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Hur påverkar höftlinjen patientens tillfrisknande: En litteraturstudie2017Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    BackgroundA fast-track system was introduced do topeople suffer from low-energy trauma with a suspected hip fracture.Thispathway up comewas to minimize the suffering a was introduced to bypass the emergency department to win time and minimizes the numbers of movement and getsthe patient faster on to the operating table.MethodsThe aim ofthis study was toexplore howthe pathway have any positiveeffects for the patient through analyzing made studies on the subject. Twelve studies wereused toanswer the aim of this study.All twelve were analyzedtrough SBU:s model for analysis.Both studies with qualitative and quantitative design wereused to answer the aim and to give it a deeper understanding. ResultsThere was an advantage for the patient in the pathway with the fewer new faces in anoften confused and painfulmomentwhich gives the patient a calmer and quicker recovery. The compassion and knowledge of the patient was bigger if the same person took care of the patient through the process. The gain in time was only a fact up untilthe x-ray after that the waitingtimebecame the same with orwithout pathway. ConclusionThe studies show an advantage for the patient with the pathway up to a point after that point there still is room for more research and change in the pathway to optimize for the patient and caregiver.

  • 37.
    Ahlgren, Helén
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Dialysberoendets påverkan på det dagliga livet: en kvalitativ intervjustudie2013Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Behov av dialysbehandling är en omvälvande förändring av patientens livsvärld. Behandlingen är livsuppehållande fram till dess att eventuell möjlighet till njurtransplantation ges. Trötthet samt viktuppgång mellan dialysbehandlingarna, orsakad av minskad filtration i njurarna har i tidigare studier framställts som försämrad livskvalitet vid dialysberoende. Hur beroendet av behandling påverkar det dagliga livet är dock personligt och varierande.

    Syfte: Syftet med studien var att beskriva hur patienter upplevde att vara beroende av dialysbehandling.

    Metod: Intervjuer gjordes med nio informanter som lever med behov av dialysbehandling.  Intervjumaterialet analyserades därefter med kvalitativ innehållsanalys, enligt Graneheim och Lundman.

    Resultat: Trots undervisning före dialysstart om vad beroendet kan komma att innebära, beskrevs beskedet som chockartat när de förstod att dialysberoendet var livslångt. Tidsåtgången för behandling minskade möjligheterna att arbeta. Dialysberoendet påverkade relationen till närstående. Betydelsen av delaktighet i behandlingsbeslut, planering och genomförande beskrevs som en känsla av självständighet och ökad egenkontroll. Möjlighet till njurtransplantation sågs som ett hopp.

    Slutsats: De hälsovinster som de dialysberoende patienterna beskrev genom möjlighet till delaktighet och självständighet, ansågs medverka till ökad livskvalitet – i väntan på hoppet om njurtransplantation.

  • 38.
    Ahlgren, Helén
    et al.
    Region Kronoberg.
    Hörberg, Ulrica
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Kliniska examinationer, exemplet ULVE2015In: Kliniska examinationer: Handbok för sjuksköterskestudenter på grund- och avancerad nivå / [ed] Sofia Almerud Österberg, Carina Elmqvist, Lund: Studentlitteratur AB, 2015, 1, p. 115-131Chapter in book (Other academic)
  • 39.
    Ahlgren, Madeleine
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Food intake, diet-related attitudes and information sources among university students2019Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
    Abstract [en]

    A series of food surveys suggest that the dietary intake among the Swedish population has changed substantially in recent years. Fat intake has increased whereas carbohydrate intake has decreased. The reason for this change is not clear but it has been suggested to be an effect of the public breakthrough of high-fat diets such as LCHF (Low Carbohydrate High Fat).

    In this study we attempt to shed light on the associations between food intake, attitudes to different diets and the information sources with regard to food, nutrition and health.

    The study is based on data collected from 311 students at the Linnaeus University, from 2015 through 2017. Food intake was identified through three-day food records using Dietist Net software. Opinions about diets, and the degree to which different sources of information were used to obtain diet-related information, were evaluated through questionnaires. Where applicable, Pearson’s correlation tests were performed in SPSS.

    In general, the students reported a low intake of iron, carbohydrates and alcohol as well as a high intake of dietary fiber, folate and selenium, relative to Nordic Nutrition Recommendations and national food surveys. Out of ten selected diets, the students ranked Nordic Nutrition Recommendations and the Mediterranean diet as the healthiest diets and the LCHF and Atkins diets as the least healthy diets. The correlation tests identified a number of associations between dietary intake and opinions about diets. Similar diets were associated to each other, such as Paleo, LCHF and Atkins diet on one hand, and Nordic Nutrition Recommendations, Vegan, Low-fat and Weight Watchers diet on the other hand. However, the Mediterranean diet, Gluten-free and 5:2 diets were associated with both low-carbohydrate diets and high-carbohydrate diets. As previous research has suggested, an association between media use and attitudes to diets which is reflected in dietary intake, can be observed. The main conclusion is that there are associations between and within reported dietary intake, information sources regarding cooking, diets and health and reported opinions regarding different diets. However, causality cannot be elucidated by this analysis.

  • 40.
    Ahlin, Charlotta
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Graae, Linda
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Persson, Ulrika
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Ett dilemma på liv och död. En systematisk litteraturstudie om när vuxna patienter väljer att avsluta livsuppehållande hemodialysbehandling2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 41.
    Ahlström, Gerd
    et al.
    Lund University.
    Nilsen, Per
    Linköping University.
    Benzein, Eva
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Behm, Lina
    Lund University.
    Wallerstedt, Birgitta
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Persson, Magnus
    Lund University.
    Sandgren, Anna
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Implementation of knowledge-based palliative care in nursing homes and pre-post post evaluation by cross-over design: a study protocol2018In: BMC Palliative Care, ISSN 1472-684X, E-ISSN 1472-684X, Vol. 17, article id 52Article in journal (Refereed)
    Abstract [en]

    Background: The demography of the world is changing as the population is ageing. Because of this change to a higher proportion of older people, the WHO has called for improved palliative care for older persons. A large number of all deaths in the industrialised world occur while older people are living in nursing homes and therefore a key question becomes how the principles of palliative care can be implemented in that context. The aims of this study are: a) to describe a model of an educational intervention with the goal of implementing knowledge-based palliative care in nursing homes, and b) to describe the design of the evaluation of the effectiveness regarding the implementation of knowledge-based palliative care. Methods/design: A complex intervention is evaluated by means of a cross-over design. An educational intervention concerning palliative care consisting of five seminars during 6 months for staff and managers has been developed and conducted in 20 nursing homes in two counties. Before the intervention started, the feasibility was tested in a pilot study conducted in nursing homes not included in the main study. The intervention is evaluated through a non-randomized experimental design with intervention and control groups and pre- and post-assessments. The evaluation includes older persons living in nursing homes, next-of-kin, staff and managers. Data collection consists of quantitative methods such as questionnaires and register data and qualitative methods in the form of individual interviews, focus-group interviews and participant observations. Discussion: The research will contribute to new knowledge about how to implement knowledge-based palliative care in a nursing home setting. A strength of this project is that the Medical Research Council framework of complex intervention is applied. The four recommended stages, Development, Feasibility and piloting, Evaluation and Implementation, are combined for the educational intervention, which functions as a strategy to achieve knowledge-based palliative care in the nursing homes. Implementation is always a question of change and a good theoretical understanding is needed for drawing valid conclusions about the causal mechanisms of change. The topic is highly relevant considering the world's ageing population. The data collection is completed and the analysis is ongoing.

  • 42.
    Ahlström Thuresson, Linda
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Andersson, Lenita
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    ”Att vara utanför normen”: En litteraturstudie om vuxnas upplevelse att leva med ADHD.2019Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [sv]

    Bakgrund: Tidigare studier visar att mellan 5-10% av alla barn och 3-10% av dagens vuxna har ADHD ( Attention-Deficit/Hyperactivity Disorder). Bakomliggande orsaker till ADHD är idag inte helt klarlagt. Individer med ADHD har symtom som koncentrationsproblem, hyperaktivitet och impulsivitet vilket påverkar deras dagliga liv. 

    Syfte: Syftet med studien var att belysa vuxnas upplevelser av att leva med ADHD.

    Metod: En litteraturstudie utfördes på fem självbiografier som kvalitetsgranskades och analyserades med hjälp av Lundmans & Hällgren Granheims (2012) kvalitativa manifesta innehållsanalys.

    Resultat: Att leva med ADHD innebär många svårigheter. Det framkom samstämmiga uppgifter som beskrev känslan av att vara annorlunda, utanförskap, dålig självkänsla. För att klara vardagen krävdes ett ökat behov av strategier och rutiner samt stöd från familjen. 

    Slutsats: Individer med ADHD, upplever svårigheter i vardagen som medför både mentalt och socialt lidande. Det kan finnas ett behov av att sjuksköterskan får en fördjupad förståelse för hur det är att leva med ADHD, likaså på vilket sätt sjuksköterskan kan hjälpa och vägleda dessa individer vid kontakt med sjukvården.

  • 43.
    Ahmad Ghafour, Soz
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
    Kan behandling med antidepressiva läkemedel påverka sjukdomens svårighetsgrad och självmordstankar/självmordshändelser hos barn och ungdomar med egentlig depression?2018Independent thesis Basic level (degree of Bachelor), 180 HE creditsStudent thesis
    Abstract [en]

    Abstract

    Suicide is a public health problem that, in addition to loss of human life, leads to extensive psychological suffering and impairment of the health of relatives. It is common that suicide occurs under the influence of mental illness such as personality disorders and depression. Depression is a serious condition that often causes severe suffering. Depression can affect all ages, i.e. children, adolescents, adults and the elderly and it is as costly as heart disease. In Sweden, depression is one of the most common psychiatric diagnoses. About 19 percent of the population (16-84 years) have been diagnosed with depression at least once in their lifetime.  Of these, almost one in three have been diagnosed more than once. The affected individual performs poorly in daily activities such as school, work and in social settings. Additionally, there is increased risk of suicide in depressed individuals. Accordingly, it is important to treat depression to reduce suffering. Depression in children was accepted as the same disease as in adults since 1980. Today, depression is treated primarily with first-line therapy SSRIs. The aim of this work was to examine the effect and safety of antidepressants in the treatment of major depresive disorder in chlidren and adolescents with special reference to suicidal activity and self-injury. To implement this study, scientific articles were obtained in Pubmed, and five articles were selected. Study 1 showed that the combination of fluoxetine and CBT, cognitive behavior therapy, had better effect than treatment with only flouxetin or with only CBT. Study 2 showed that suicidal events and ideation were least among the group treated with the combination of fluoxetine and CBT compared to the treatment with only fluoxetine or only CBT. Study 3 showed that more suicide-related events occurred among the group with previous non-suicidal self-injury, NSSI. Study 4 resulted in greater medical response and better remission in escitalopram patients compared to placebo. Study 5 showed that treatment with venlafaxine caused serious adverse events that led to many discontinuing treatment. Treatment with antidepressants, especially in combination with CBT, can reduce the severity of depression in children and adolescents and reduce suicidal ideation and suicide attempts in some patients. In cases of treatment failure a risk of suicide and self-injury remains. Previous self-injury increases the risk of future self-injury as well as the risk of future suicide attempts.

  • 44.
    Ahmady, Soleiman
    et al.
    Shahid Beheshti University of Medical Sciences, Iran;Karolinska Institutet, Sweden.
    Changiz, Tahereh
    Isfahan University of Medical Sciences, Iran.
    Masiello, Italo
    Karolinska Institutet, Sweden.
    Hamadanchi, Arya
    University of Social and Rehabilitation Sciences, Iran.
    Development and psychometrics properties of an instrument for assessing faculty development programs from a broader perspective2016In: Biosciences Biotechnology Research Asia, ISSN 0973-1245, Vol. 13, no 1, p. 319-325Article in journal (Refereed)
    Abstract [en]

    The present study proposed a new instrument for the assessment of the current faculty development programs at Iranian medical universities. Although the literature concerning the subject of faculty development activities has already identified strengths and weakness of such programs, it is still questionable whether these activities can be assessed using a pedagogical and managerial comprehensive approach. Therefore, it was determined to develop an instrument to examine faculty development activities that address all components of programs from planning and implementing to evaluating phases, with the possibility of utilizing this instrument as a tool to assess faculty development activities.

  • 45.
    Ahmedova, Renin
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Förhållandena inom refraktiv kirurgi i Sverige, vilka metoder används och vilka komplikationer finns?2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
    Abstract [en]

    Refractive surgery is an effective method for correcting visual refractive errors. The method has evolved quickly over the past decade.

    The aim of this study was to examine what refractive surgery is in Sweden today. What complications exist and which methods are used, are described by making a presentation of the refractive surgery techniques FS-LASIK, LASEK, TransPRK and RLE. This was done by a survey to find out the various complications between different age groups.

    A web-based survey was disseminated trough social media like Facebook, different forum sites and e-mail. The survey was also submitted to various eye clinics. The respondents were asked questions about their age, gender, the surgical method used and the complications after surgery.

    The results of the survey showed that there is no difference in the complication rate between the different age groups. Complications only depend on the type of method used and the patient’s refractive errors.

  • 46.
    Ahnesjö, Jonas
    et al.
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Bergman, Patrick
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Effects on white blood cells in senior citizens during post exercise recovery in three different environments (indoors, simulated outdoors and outdoors)2016Conference paper (Refereed)
    Abstract [en]

    Introduction

    Natural environments are known to promote health and may also provide extraordinary conditions for post exercise recovery (Kuo 2015). In the project Health Effects of Recreation Outdoors (HERO) we explore the hypothesis that post exercise recovery in natural environments may be reflected in white blood cell counts (WBC). In our study 50 seniors (age >65 years) performed moderate physical activity (20 min) followed by passive recovery (2h) in three different environments (indoors, simulated outdoors and “true” outdoors).

    Method

    The experimental setup was a randomized cross-over design, thus all test persons did all treatments in a randomized order. We sampled white blood cells (WBC-diff), which were used to detect and quantify inflammatory response.

    Results

    Our early findings provide some support for the hypothesis that environment may impose differences in recovery effectiveness. White blood cell count (WBC-diff) appears to differ between the treatments and there is a significant interaction between sampling time and recovery environment in the monocytes, suggesting that the monocyte numbers differ, not only between sampling times but also between environments. In addition, WBC also show that some of the test persons develop leukocytosis during exercise and that white blood cell levels decrease rapidly immediately post exercise to levels significantly lower than base line values.

    Discussion

    Our results suggest that moderate physical activity in senior citizens may result in acute leukocytosis (see e.g. Sand et. al. 2013) and that recovery effectiveness (e.g in monocyte response) may be dependent upon environmental factors. The clinical importance of our results are not fully understood but there has been suggested an “open window” immediately post exercise in which infection risk may be elevated (Pedersen & Toft 2000) and it is possible that recovery out of doors may reduce this risk.

    References

    Sand, K., L, Flatebo, K., Andersen, M., B., Maghazachi, A., A. (2013) World J Exp Med 20; 3(1): 11-20

    Pedersen, B., K. & Toft, A., D. (2000) Br J Sports Med 34:246–251

    Kuo, M. (2015) Frontiers in Psychology 6:1-8

  • 47.
    Ahnesjö, Jonas
    et al.
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Bergman, Patrick
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Outdoor Exercise is More Efficient than Indoor Exercise in Senior Citizens. Physiological Evidence from the HERO Project2018Conference paper (Refereed)
    Abstract [en]

    INTRODUCTION: IntroductionPhysical exercise has been proven beneficial for health in all ages. In elderly, physical exercise, may contribute to prolonged life with maintained high quality and less costs associated with health care for society. In this study we explore if exercise out of doors may provide extra benefits as compared to exercise indoors and we measure power output, lactate levels and perceived effort in 49 senior citizens performing 20 minutes of moderate physical activity.METHODS:MethodThe HERO project is a randomized cross-over experiment with three different treatments <indoors, simulated="" outdoors="" and="">. The study sample consisted of 49 healthy senior citizens. They performed 20 minutes moderate intensity physical activity on an ergometer bike in all three conditions. Before immediately after and at minutes 10, 20, 30, 60 and 120 we sampled blood lactate. Power output was computed at 7 occasions during the 20 minutes of cycling, as was the rating of perceived exertion . Data was analyzed using mixed linear models. RESULTS:ResultsOur findings show that there were no differences between the two indoor treatments in any of the measured variables. In the outdoor treatment, however, there were significant effects on blood lactate levels and power output but not in perceived exertion, suggesting that exercise out of doors makes the test person more efficient although the experience of effort stay unaffected.CONCLUSION:Discussion/conclusionsOur results support the notion that the outdoors may provide extraordinary conditions for exercise, not only because it appear to results in more exercise/effort, the outdoors is also an “arena” with high availability and most often totally for free. Previous results from the HERO project also suggests that white blood cell counts are affected by the outdoor treatment, something that may be related to the observed increased power output herein

  • 48.
    Ahnesjö, Jonas
    et al.
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Danielsson, Tom
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Recreational fishing in an educational intervention context promotes awareness and knowledge about nature in schoolchildren2013Conference paper (Other academic)
    Abstract [en]

    Outdoor activities may be intuitively associated with interest for nature and environmental concern. However, most scientific studies suggest that no such correlation exists. In this quantitative study we have used a questionnaire and explored the hypothesis that a one day educational intervention may be a successful tool in increasing environmental awareness, interest for nature and interest for recreational fishing. We present evidence suggesting that educational interventions in which young people are exposed to natural environments in a recreational fishing context have positive effects on interest for nature and recreational fishing, knowledge about nature and environmental awareness. Our findings also reveal that frequency of nature visits does not correlate with self estimated interest for nature.  We also show that the observed effects of the educational intervention “Klassdraget” appear to be larger for the girls which are, by tradition, less interested in recreational fishing as compared to boys.

  • 49.
    Ahnesjö, Jonas
    et al.
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Karlsson, Peter S.
    Linnaeus University, School of Business and Economics, Department of Economics and Statistics.
    Bergman, Patrick
    Linnaeus University, Faculty of Social Sciences, Department of Sport Science.
    Benefits of outdoor exercise and recovery outdoors in elderly2019In: HEPA Europe, Odense, Denmark, August 28-30, 2019: abstract book, 2019, p. 38-38Conference paper (Refereed)
    Abstract [en]

    Purpose: The purpose of this study was to test the hypothesis that the ”outdoors” has an added health effect on top of that of physical activity. This hypothesis is based on the fairly extensive volume of evidens suggesting that the outdoor environment is beneficial for overall health. We, however, consider most previous studies insufficiently designed in order to draw causal relationship between spending time outdoors and examined health parameters. In this study we state that our experimental design allows us to do just that. 

    Methods:

    In this randomized cross-over experimental design, 49 healthy subjects (+65 years, 27 female) performed a standardized submaximal bike ergometer test in three different environments (indoors, simulated outdoors and outdoors). The test consisted of 20 minutes cycling and subjects were instructed to stay between 11-13 at the Borg RPE scale (i.e. moderate intensity). Each test was followed by two hours of passive recovery. We measured power output, heart rate, lactate and counts of five fractions (lymphocytes, monocytes, neutrophiles, basophiles and eosinophiles) of white blood cells (leukocytes) in circulation.

    Results:

    Our results revealed that the outdoor treatment resulted in higher levels of lactate, higher heart rate and higher power output despite that there were no differences in Borg RPE-rating between the treatments. The white blood cell analysis showed an increase of circulating leukocytes in almost all fractions immediately post exercise in all treatments. Numbers decreased rapidly post exercise and the lymphocyte numbers stayed well under baseline for more than one hour during recovery. This is referred to as an “open window” where the immune function is temporarily suppressed and there is an elevated risk of infection of primarily URTI.

    Conclusions:

    Our results not only suggest that exercise is more efficient out of doors such that more exercise/effort is obtained but also that recovery outdoors may be a way to decrease the risk of infections due to exercise induced immune suppression. The risk of getting an infection is known to be generally lower out of doors. Taken together, our results support the notion that exercising and spending time outdoors indeed is beneficial for health in senior citizens.

  • 50.
    Aho, Anna Carin
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences.
    Living with recessive limb-girdle muscular dystrophy: affected young adults’ and parents’ perspectives, studied througha salutogenic framework2017Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Aim: The overall aim of this thesis, using a salutogenic framework, was to develop knowledge about experiences and perceptions of living with recessive limb-girdle muscular dystrophy and its influences on health, from the affected young adults’ and their parents’ perspectives.

    Methods: A qualitative explorative and descriptive study design was used. Semi-structured interviews were held with 14 young adults diagnosed with recessive limb-girdle muscular dystrophy, aged 20–0 years, and 19 parents. Data analyses were conducted using content analysis (I, II, III) and phenomenography (IV). In order to mirror the interview data, the participants also answered the 13-item sense of coherence questionnaire.

    Findings: Recessive limb-girdle muscular dystrophy has a major impact on the affected young adults’ and their parents’ lives as the disease progresses. Health described in terms of well-being was thus perceived to be influenced, not only by physical, emotional and social consequences due to the disease and worry about disease progression but also by external factors, such as accessibility to support provided by society and other people’s attitudes. There was, however, a determination among the participants to try to make the best of the situation. The importance of being able to mobilize internal resources, having social support, meaningful daily activities, adapted environment, the young adult being seen as a person and having support from concerned professionals, including personal assistance when needed, was thereby described. Self-rated sense of coherence scores varied. Those who scored above or the same as median among the young adults (≥56) and the parents (≥68) expressed greater extent satisfaction regarding social relations, daily activities and external support than those who scored less than median.

    Conclusion: This thesis highlights the importance of early identification of personal perceptions and needs to enable timely health-promoting interventions. Through dialogue, not only support needed for the person to comprehend, manage and find meaning in everyday life can be identified, but also internal and external resources available to enhance health and well-being, taking into account the person’s social context as well as medical aspects.

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