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  • 1.
    Bremer, Anders
    University of Borås, Sweden.
    Hjärtstopp utanför sjukhus2012In: Medicinska Riksstämman, 28-30 nov 2012: Tema Framtidens hälsa, 2012Conference paper (Other academic)
  • 2.
    Carlsson, Martin
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry. Kalmar County Hospital.
    Brudin, Lars
    Kalmar County Hospital;Univ Hosp Linköping.
    Wanby, Pär
    Kalmar County Hospital.
    Directly measured free 25-hydroxy vitamin D levels show no evidence of vitamin D deficiency in young Swedish women with anorexia nervosa2018In: Eating and Weight Disorders, ISSN 1124-4909, E-ISSN 1590-1262, Vol. 23, no 2, p. 247-254Article in journal (Refereed)
    Abstract [en]

    Purpose Anorexia nervosa (AN) is an eating disorder characterized by low fat mass complicated by osteoporosis. The role of circulating vitamin D in the development of bone loss in AN is unclear. Fat mass is known to be inversely associated with vitamin D levels measured as serum levels of total, protein-bound 25-hydroxyvitamin D, but the importance of directly measured, free levels of 25(OH)D has not been determined in AN. The aim of this study was to investigate vitamin D status, as assessed by serum concentrations of total and free serum 25(OH)D in patients with AN and healthy controls. Methods In female AN patients (n = 20), and healthy female controls (n = 78), total 25(OH)D was measured by LC-MS/MS, and free 25(OH)D with ELISA. In patients with AN bone mineral density (BMD) was determined with DEXA. Results There were no differences between patients and controls in total or free S-25(OH)D levels (80 +/- 31 vs 72 +/- 18 nmol/L, and 6.5 +/- 2.5 vs 5.6 +/- 1.8 pg/ml, respectively), and no association to BMD was found. In the entire group of patients and controls, both vitamin D parameters correlated with BMI, leptin, and PTH. Conclusions The current study did not demonstrate a vitamin D deficiency in patients with AN and our data does not support vitamin D deficiency as a contributing factor to bone loss in AN. Instead, we observed a trend toward higher vitamin D levels in AN subjects compared to controls. Measurement of free vitamin D levels did not contribute to additional information.

  • 3.
    Le Reste, Jean Yves
    et al.
    Univ Bretagne Occidentale, France.
    Nabbe, Patrice
    Univ Bretagne Occidentale, France.
    Rivet, Charles
    Univ Bretagne Occidentale, France.
    Lygidakis, Charilaos
    AIMEF, Bologna, Italy.
    Doerr, Christa
    Allgemein Med Hsch Gottingen, Germany.
    Czachowski, Slawomir
    Nicholas Copernicus Univ, Poland.
    Lingner, Heidrun
    Allgemein Med Hsch Hannover, Germany.
    Argyriadou, Stella
    Greek Assoc Gen Practitioners ELEGEIA, Greece.
    Lazic, Djurdjica
    Univ Zagreb, Croatia.
    Assenova, Radost
    Paisij Hilendarski Univ Plovdiv, Bulgaria.
    Hasaganic, Melida
    Univ Sarajevo, Bosnia-Herzegovina.
    Munoz, Miquel Angel
    IDIAP Jordi Gol, Spain.
    Thulesius, Hans
    Lund University, Sweden.
    Le Floch, Bernard
    Univ Bretagne Occidentale, France.
    Derriennic, Jeremy
    Univ Bretagne Occidentale, France.
    Sowinska, Agnieska
    Nicholas Copernicus Univ, Poland.
    Van Marwijk, Harm
    Vrije Univ Amsterdam Med Ctr, Netherlands.
    Lietard, Claire
    Univ Bretagne Occidentale, France.
    Van Royen, Paul
    Univ Antwerp, Belgium.
    The European General Practice Research Network Presents the Translations of Its Comprehensive Definition of Multimorbidity in Family Medicine in Ten European Languages2015In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 10, no 1, article id e0115796Article in journal (Refereed)
    Abstract [en]

    Background Multimorbidity, according to the World Health Organization, exists when there are two or more chronic conditions in one patient. This definition seems inaccurate for the holistic approach to Family Medicine (FM) and long-term care. To avoid this pitfall the European General Practitioners Research Network (EGPRN) designed a comprehensive definition of multimorbidity using a systematic literature review. Objective To translate that English definition into European languages and to validate the semantic, conceptual and cultural homogeneity of the translations for further research. Method Forward translation of the EGPRN's definition of multimorbidity followed by a Delphi consensus procedure assessment, a backward translation and a cultural check with all teamsto ensure the homogeneity of the translations in their national context. Consensus was defined as 70% of the scores being higher than 6. Delphi rounds were repeated in each country until a consensus was reached Results 229 European medical expert FPs participated in the study. Ten consensual translations of the EGPRN comprehensive definition of multimorbidity were achieved. Conclusion A comprehensive definition of multimorbidity is now available in English and ten European languages for further collaborative research in FM and long-term care.

  • 4.
    Olander, Agnes
    et al.
    University of Borås, Sweden.
    Andersson, Henrik
    University of Borås, Sweden.
    Sundler, Annelie J.
    University of Borås, Sweden.
    Bremer, Anders
    Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences. University of Borås, Sweden.
    Ljungström, Lars
    University of Gothenburg, Sweden;Skaraborg Hospital, Sweden.
    Hagiwara, Magnus Andersson
    University of Borås, Sweden.
    Prehospital characteristics among patients with sepsis: a comparison between patients with or without adverse outcome2019In: BMC Emergency Medicine, ISSN 1471-227X, E-ISSN 1471-227X, Vol. 19, no 1, p. 1-8, article id 43Article in journal (Refereed)
    Abstract [en]

    Background The prehospital care of patients with sepsis are commonly performed by the emergency medical services. These patients may be critically ill and have high in-hospital mortality rates. Unfortunately, few patients with sepsis are identified by the emergency medical services, which can lead to delayed treatment and a worse prognosis. Therefore, early identification of patients with sepsis is important, and more information about the prehospital characteristics that can be used to identify these patients is needed. Based on this lack of information, the objectives of this study were to investigate the prehospital characteristics that are identified while patients with sepsis are being transported to the hospital by the emergency medical services, and to compare these values to those of the patients with and without adverse outcomes during their hospital stays. Methods This was a retrospective observational study. The patients' electronic health records were reviewed and selected consecutively based on the following: retrospectively diagnosed with sepsis and transported to an emergency department by the emergency medical services. Data were collected on demographics, prehospital characteristics and adverse outcomes, defined as the in-hospital mortality or treatment in the intensive care unit, and analysed by independent sample t-test and chi-square. Sensitivity, specificity and likelihood ratio, of prehospital characteristics for predicting or development of adverse outcome were analysed. Results In total, 327 patients were included. Of these, 50 patients had adverse outcomes. When comparing patients with or without an adverse outcome, decreased oxygen saturation and body temperature, increased serum glucose level and altered mental status during prehospital care were found to be associated with an adverse outcome. Conclusions The findings suggests that patients having a decreased oxygen saturation and body temperature, increased serum glucose level and altered mental status during prehospital care are at risk of a poorer patient prognosis and adverse outcome. Recognizing these prehospital characteristics may help to identify patients with sepsis early and improve their long-term outcomes. However further research is required to predict limit values of saturation and serum glucose and to validate the use of prehospital characteristics for adverse outcome in patients with sepsis.

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