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  • 1.
    Engberg, Anna E.
    et al.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nilsson, Per H.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Mollnes, Tom Eirik
    Rosengren-Holmberg, Jenny P.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nicholls, Ian A.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nilsson, Bo
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    The ratio between C4 and C4BP adsorbed from plasma predicts cytokine generation induced by artificial polymers in contact with whole blood2012In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 217, no 11, p. 1211-1211Article in journal (Other academic)
  • 2. Hamad, Osama A.
    et al.
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nilsson, Bo
    Non-proteolytically activated C3 promotes binding of activated platelets and platelet-derived microparticles to leukocytes via CD11b/CD182012In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 217, no 11, p. 1191-1191Article in journal (Other academic)
  • 3.
    Harboe, M.
    et al.
    Oslo University Hospital Rikshospitalet, Norway.
    Johnson, C.
    Oslo University Hospital Rikshospitalet, Norway.
    Nymo, S.
    Nordland Hospital, Norway.
    Ekholt, K.
    Oslo University Hospital Rikshospitalet, Norway.
    Schjalm, C.
    Oslo University Hospital Rikshospitalet, Norway.
    Lindstad, J. K.
    Oslo University Hospital Rikshospitalet, Norway.
    Pharo, A.
    Oslo University Hospital Rikshospitalet, Norway.
    Hellerud, B. C.
    Oslo University Hospital Rikshospitalet, Norway.
    Nilsson Ekdahl, Kristina
    Uppsala University.
    Mollnes, T. E.
    Oslo University Hospital Rikshospitalet, Norway ; Nordland Hospital, Norway.
    Nilsson, Per H.
    Oslo University Hospital Rikshospitalet, Norway.
    Molecular modelling showed optimal fit between TSR5 in trimeric properdin and C345C in the C3b moiety for stabilization of the alternative convertase, whereas binding to molecular patterns in myeloperoxidase, endothelial cells and Neisseria meningitides was indirectly mediated by initial C3 activation2016In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 221, no 10, p. 1205-1205Article in journal (Refereed)
  • 4.
    Huang, Shan
    et al.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nilsson, Per H.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Sandholm, Kerstin
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Elmlund, Louise
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nicholls, Ian A.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Regulation of complement in whole blood by heparin molecularly imprinted polymer particles2012In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 217, no 11, p. 1199-1199Article in journal (Other academic)
  • 5. Klapper, Yvonne
    et al.
    Hamad, Osama
    Teramura, Yuji
    Leneweit, Gero
    Nienhaus, Gerd Ulrich
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nilsson, Bo
    Investigation of complement activation by neutral liposomes2012In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 217, no 11, p. 1179-1180Article in journal (Other academic)
  • 6. Nilsson, Bo
    et al.
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    The tick-over theory revisited: Is C3 a contact-activated protein?2012In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 217, no 11, p. 1106-1110Article, review/survey (Refereed)
    Abstract [en]

    The tick-over theory was first introduced in the 1970s to explain the presence of the initial C3b molecules, which are able to trigger complement activation by the alternative pathway in human plasma under physiological conditions. After the identification of the thioester, the predominant hypothesis has been that this bond is hydrolyzed at a slow but constant rate by nucleophilic attack by H2O, leading to the generation of C3(H2O). Here we put forward the hypothesis that the rate of hydrolysis of C3 to C3(H2O) may be greatly accelerated by the interaction between C3 and a number of biological and artificial interfaces, including gas bubbles, biomaterial surfaces and different lipid surfaces and complexes. We therefore propose that C3 should preferentially be regarded as a contact activated protein rather than a target for passive, random hydrolysis in the fluid phase. (C) 2012 Elsevier GmbH. All rights reserved.

  • 7.
    Nilsson Ekdahl, Kristina
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences. Uppsala University.
    Teramura, Yuji
    Uppsala University;Univ Tokyo, Japan.
    Asir, Sana
    Uppsala University.
    Manell, Elin
    Swedish University of Agricultural Sciences.
    Biglarnia, Alireza
    Skåne Univ Hosp.
    Jensen-Waern, Marianne
    Swedish University of Agricultural Sciences.
    Nilsson, Bo
    Uppsala University.
    Protective role of PEG conjugated phospholipid in reducing ischemic reperfusion injury in two allogeneic pig kidney transplant models2016In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 221, no 10, p. 1184-1184Article in journal (Other academic)
  • 8.
    Orrem, H. L.
    et al.
    Oslo University Hospital, Norway ; University of Oslo, Norway.
    Nilsson, Per H.
    Oslo University Hospital, Norway ; University of Oslo, Norway.
    Barratt-Due, A.
    Oslo University Hospital, Norway.
    Pische, S. E.
    Oslo University Hospital, Norway.
    Grindheim, G.
    Rikshospitalet, Oslo University Hospital, Norway.
    Garred, P.
    University of Copenhagen, Denmark.
    Husebye, T.
    Oslo University Hospital Ullevål, Norway ; University of Oslo, Norway.
    Andersen, G. O.
    Oslo University Hospital Ullevål, Norway ; University of Oslo, Norway.
    Mollnes, T. E.
    Oslo University Hospital, Norway ; University of Oslo, Norway ; Research Laboratory Nordland Hospital, Norway ; University of Tromsø, Norway ; Norwegian University of Science and Technology, Norway.
    Complement activation in acute heart failure following myocardial infarction2016In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 221, no 10, p. 1203-1204Article in journal (Refereed)
  • 9.
    Otterdal, K.
    et al.
    Oslo University Hospital Rikshospitalet, Norway.
    Portillo, A.
    Hospital San Pedro-Center of Biomedical Research from La Rioja (CIBIR), Spain.
    Astrup, E.
    Oslo University Hospital Rikshospitalet, Norway.
    Ludviksen, J. K.
    Nordland Hospital, Norway.
    Schjalm, C.
    Oslo University Hospital Rikshospitalet, Norway.
    Raoult, D.
    Université de la Mediterranée, France.
    Olano, J. P.
    University of Texas Medical Branch, USA.
    Halvorsen, B.
    Oslo University Hospital Rikshospitalet, Norway.
    Oteo, J. A.
    Hospital San Pedro-Center of Biomedical Research from La Rioja (CIBIR), Spain.
    Aukrust, P.
    Oslo University Hospital Rikshospitalet, Norway.
    Mollnes, T. E.
    Nordland Hospital, Norway ; Oslo University Hospital Rikshospitalet, Norway.
    Nilsson, Per H.
    Oslo University Hospital Rikshospitalet, Norway.
    Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo2016In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 221, no 10, p. 1204-1205, article id 161Article in journal (Refereed)
  • 10.
    Sandholm, Kerstin
    et al.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Henningsson, Anna J.
    Bergstrom, Sven
    Ernerudh, Jan
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Complement activation and phagocytosis in vitro of two strains of Borrelia burgdorferi S.L2012In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 217, no 11, p. 1153-1153Article in journal (Other academic)
  • 11. Teramura, Yuji
    et al.
    Nilsson, Per H.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Nilsson Ekdahl, Kristina
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Magnusson, Peetra U.
    Qu, Hongchang
    Ricklin, Daniel
    Hong, Jaan
    Lambris, John D.
    Nilsson, Bo
    Autoregulation of thromboinflammation on biomaterials and cells by a novel therapeutic coating technique2012In: Immunobiology, ISSN 0171-2985, E-ISSN 1878-3279, Vol. 217, no 11, p. 1140-1140Article in journal (Other academic)
1 - 11 of 11
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