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  • 1.
    Baskaran, Karthikeyan
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Lewis, Peter
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosen, Robert
    Biomedical and X-Ray Physics.
    Unsbo, Peter
    Biomedical and X-Ray Physics.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Effects of Optical Defocus on Resolution Acuity in Preferred Retinal Locus2011Ingår i: Invest Ophthalmol Vis Sci 2011;52: E-Abstract 1900., 2011, Vol. 52, nr 6Konferensbidrag (Refereegranskat)
    Abstract [en]

    PurposeResolution acuity in the peripheral visual field is primarily limited by retinal sampling. In healthy eyes, the correction of peripheral refractive errors does not produce significant visual benefits other than improved detection and low contrast acuity. However, studies (Lundstrom L et al, Optom Vis Sci, 2007;84:1046-52) have shown that peripheral refractive corrections improve resolution acuity in subjects with central visual field loss (CFL) who have an established preferred retinal locus (PRL). The aim of this study was to evaluate the effect of optical defocus on high contrast resolution acuity in the PRL. MethodsResolution acuity was evaluated under spherical defocus in the PRL of three low vision subjects (mean age 75 years) with long standing CFL (due to age-related macular degeneration). Off-axis refractive error at the PRL was measured by an open-field COAS-HD VR aberrometer and was corrected accordingly. The PRL for subject 1 was located at 10{degrees} in the temporal visual field (left eye), subject 2 at 20{degrees} in the nasal visual field (right eye) and subject 3 at 15{degrees} in the inferior visual field (left eye). Stimuli consisting of high-contrast Gabor patches with a visible diameter of 3{o} were presented on a CRT monitor situated 1.0 meter from the subject. Resolution thresholds for static visual acuity (SVA) and dynamic visual acuity (DVA) were obtained using an adaptive Bayesian algorithm. Fixation was aided using illuminated concentric rings covering {+/-}25{degrees} in the visual field. Defocus was altered in 1D steps up to {+/-}4D. When measuring DVA, the sine-wave gratings drifted within the Gaussian envelope at an angular velocity of 1{degrees}/sec. ResultsResolution thresholds for both SVA and DVA in the PRL varied significantly with the amount of optical defocus. The results show a 2 - 3 line decrease (logMAR) in SVA and DVA with 4 D positive and negative defocus. There was no significant difference between SVA and DVA with increasing defocus. In the absence of defocus, SVA was significantly better than DVA in the PRL. ConclusionsDefocus as low as one dioptre has an impact on both static and dynamic high contrast resolution acuity for CFL subjects using a PRL. The results of this study suggest that, for CFL subjects using a PRL, resolution acuity is not only sampling limited but also influenced by the optics of the eye.

  • 2.
    Baskaran, Karthikeyan
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosen, R.
    Lewis, Peter
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Unsbo, P.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Benefit of Adaptive Optics Aberration Correction at Preferred Retinal Locus2012Ingår i: Optometry and Vision Science, ISSN 1040-5488, E-ISSN 1538-9235, Vol. 89, nr 9, s. 1417-1423Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    PURPOSE.: To investigate the effect of eccentric refractive correction and full aberration correction on both high- and low-contrast grating resolution at the preferred retinal locus (PRL) of a single low-vision subject with a long-standing central scotoma. METHODS.: The subject was a 68-year-old women with bilateral absolute central scotoma due to Stargardt disease. She developed a single PRL located 25 degrees nasally of the damaged macula in her left eye, this being the better of the two eyes. High- (100%) and low-contrast (25 and 10%) grating resolution acuity was evaluated using four different correction conditions. The first two corrections were solely refractive error corrections, namely, habitual spectacle correction and full spherocylindrical correction. The latter two corrections were two versions of adaptive optics corrections of all aberrations, namely, habitual spectacle correction with aberration correction and full spherocylindrical refractive correction with aberration correction. RESULTS.: The mean high-contrast (100%) resolution acuity with her habitual correction was 1.06 logMAR, which improved to 1.00 logMAR with full spherocylindrical correction. Under the same conditions, low-contrast (25%) acuity improved from 1.30 to 1.14 logMAR. With adaptive optics aberration correction, the high-contrast resolution acuities improved to 0.89/0.92 logMAR and the low-contrast acuities improved to 1.04/1.06 logMAR under both correction modalities. The low-contrast (10%) resolution acuity was 1.34 logMAR with adaptive optics aberration correction; however, with purely refractive error corrections, she was unable to identify the orientation of the gratings. CONCLUSIONS.: Correction of all aberrations using adaptive optics improves both high- and low-contrast resolution acuity at the PRL of a single low-vision subject with long-standing absolute central scotoma

  • 3.
    Hernández-Moreno, Laura
    et al.
    Univ Minho, Portugal.
    Senra, Hugo
    Univ Essex, UK;Univ Coimbra, Portugal.
    Lewis, Peter
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Moreno, Natacha
    Hosp Santa Maria Maior EPE, Portugal.
    Linhares, João
    Univ Minho, Portugal.
    Santana, Rui
    Univ NOVA, Portugal.
    Lima Ramos, Pedro
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO). Univ Minho, Portugal.
    Marques, Ana Patrícia
    Univ NOVA, Portugal.
    Macedo, António Filipe
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO). Univ Minho, Portugal.
    Cost‐effectiveness of basic vision rehabilitation (The basic VRS‐effect study): study protocol for a randomised controlled trial2020Ingår i: Ophthalmic & physiological optics, ISSN 0275-5408, E-ISSN 1475-1313Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Abstract Purpose To investigate the cost-effectiveness of a basic vision rehabilitation service (basic-VRS) in Portugal. We designed a parallel group, randomised controlled trial whose aim is to compare the effects and costs of ?usual low vision care? with a ?basic-VRS intervention? on self-reported visual ability and other psychosocial and health-related quality-of-life outcomes. Methods The trial will recruit participants that meet the following inclusion criteria: (1) visual acuity between 0.4?1.0 logMAR in the better-seeing eye, (2) cause of vision loss is diabetic retinopathy or age-related macular degeneration, (3) 18 years or older and iv) live in the community (not in nursing homes or other type of institution). Participants will be randomised to one of the study arms consisting of immediate intervention and delayed intervention. The delayed intervention group will receive ?usual care? or no intervention in the first 12 weeks. Visual acuity, contrast sensitivity and retinal structure will be assessed during the study. Results The primary outcome measure is visual ability, which will be evaluated with the Massof Activity Inventory, we expect that the intervention will raise the overall person measure or visual ability. Reading, health-related quality-of-life, anxiety and depression and social support will be also assessed. The analysis will be undertaken on an intention-to-treat basis. A cost-effectiveness analysis will be performed to provide information about the cost per unit of utility. To evaluate the cost-effectiveness of the intervention we will adopt the perspective of the healthcare system. Conclusion This study will provide additional evidence about the effects of basic-VRS on self-reported visual ability. Findings from this study should also contribute to better planning of low vision provision and, consequently, may contribute to reduce barriers to basic-VRS.

  • 4.
    Kristiansson, Håkan
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Baskaran, Karthikeyan
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Lewis, Peter
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosén, Robert
    Biomedical and X-Ray Physics.
    Unsbo, Peter
    Biomedical and X-Ray Physics.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Effect of Optical Defocus on Peripheral Resolution Acuity in Old Healthy Emmetropes2011Konferensbidrag (Refereegranskat)
    Abstract [en]

    Background:

    A recent study by Rosén et al found peripheral low contrast resolution acuity, but not high contrast acuity, to be affected by defocus in young healthy eyes. Since aging causes considerable degradation in peripheral optics even in healthy subjects we wanted to see if, older subjects were also sensitive to defocus in low contrast acuity.

     

    Purpose:

    The aim of this study was to evaluate the effect of optical defocus on high and low contrast resolution acuity in the peripheral visual field of healthy older emmetropes.

     

    Subjects:

    High- and low-contrast resolution acuity was evaluated under spherical defocus in the 20° nasal visual field of four healthy older emmetropic subjects. The off-axis refractive error at the 20° nasal visual field was measured by a COAS-HD VR aberrometer and was corrected accordingly for each subject.

     

    Methods:

    Resolution thresholds for visual acuity (VA) were obtained using stimuli consisting of high- (100%) and low- (10%) contrast gratings that were presented on a CRT monitor situated 1.0 meter from the subject. Stimuli, 3° in diameter were presented for 300 ms using a 2AFC paradigm. Two repeated measurements, for both high and low contrast, were obtained for each point of defocus in 1.0 D steps up to ±4 D at 45mm vertex distance. The results are corrected to effective defocus at the corneal plane.

     

    Results:

    Defocus had no visible effect on high contrast VA, although there was a slight decrease in VA with higher amounts of positive defocus. However, defocus was found to have a significant effect on low contrast VA. Moreover, low contrast resolution was more sensitive to positive defocus than the negative defocus.

     

    Conclusions:

    Defocus has an impact on low contrast resolution whereas no such effect was found for high contrast resolution. These results are similar to those obtained by Rosén et al1 in young eyes. These results suggest that low contrast optotypes could possibly be used for determining subjective refraction in low vision subjects.

  • 5.
    Lewis, Peter
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Improving Peripheral Vision Through Optical Correction and Stimulus Motion2016Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    The loss of central vision subsequent to macular disease is often extremely debilitating. People with central field loss (CFL) must use other peripheral areas of the retina in order to see; areas with inferior resolution capacity, which are also affected by off-axis optical errors. The overall aim of the work encompassed by this thesis was to identify and evaluate methods of improving vision for people with CFL; with focus on the effects of off-axis optical correction and stimulus motion on resolution acuity and contrast sensitivity.

    Off-axis optical errors were measured using a commercially-available COAS-HD VR open-view aberrometer. We used adaptive psychophysical methods to evaluate grating resolution acuity and contrast sensitivity in the peripheral visual field; drifting gratings were employed to   measure the effect of motion on these two measures of visual performance. The effect of sphero-cylindrical correction and stimulus motion on visual performance in healthy eyes and in subjects with CFL was also studied; in addition, the effect of adaptive optics aberration correction was examined in one subject with CFL.

    The COAS-HD aberrometer provided rapid and reliable measurements of off-axis refractive errors. Correction of these errors gave improvements in low-contrast resolution acuity in subjects with higher amounts of oblique astigmatism. Optical correction also improved high-contrast resolution acuity in most subjects with CFL, but not for healthy subjects. Adaptive optics correction improved both high and low contrast resolution acuity in the preferred retinal locus of a subject with CFL. The effect of stimulus motion depended on spatial frequency; motion of 7.5 Hz improved contrast sensitivity for stimuli of low spatial frequency in healthy and CFL subjects. Motion of 15 Hz had little effect on contrast sensitivity for low spatial frequency but resulted in reduced contrast sensitivity for higher spatial frequencies in healthy subjects. Finally, high-contrast resolution acuity was relatively insensitive to stimulus motion in the periphery.

    This thesis has served to broaden the knowledge regarding peripheral optical errors, stimulus motion and their effects on visual function, both in healthy subjects and in people with CFL. Overall it has shown that correction of off-axis refractive errors is important for optimizing peripheral vision in subjects with CFL; the use of an open-view aberrometer simplifies the determination of these errors. In addition, moderate stimulus motion can have a beneficial effect on contrast sensitivity for objects of predominantly low spatial frequency.

  • 6.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Baskaran, Karthikeyan
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Rosen, Robert
    Royal Institute of Technology KTH.
    Lundström, Linda
    Royal Institute of Technology KTH.
    Unsbo, Peter
    Royal Institute of Technology KTH.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Objectively Determined Refraction Improves Peripheral Vision2014Ingår i: Optometry and Vision Science, ISSN 1040-5488, E-ISSN 1538-9235, Vol. 91, nr 7, s. 740-746Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose. The purpose of this study was twofold: to verify a fast, clinically applicable method for determining off-axis refraction and to assess the impact of objectively obtained off-axis refractive correction on peripheral low-contrast visual acuity. Methods. We measured peripheral low-contrast resolution acuity with Gabor patches both with and without off-axis correction at 20 degrees in the nasal visual field of 10 emmetropic subjects; the correction was obtained using a commercial open-field Hartmann-Shack wavefront sensor, the COAS-HD VR aberrometer. Off-axis refractive errors were calculated for a 5-mm circular pupil inscribed within the elliptical wavefront by COAS using the instruments' inbuilt "Seidel sphere" method. Results. Most of the subjects had simple myopic astigmatism, at 20 degrees in the nasal visual field ranging from -1.00 to -2.00 DC, with axis orientations generally near 90 degrees. The mean uncorrected and corrected low-contrast resolution acuities for all subjects were 0.92 and 0.86 logMAR, respectively (an improvement of 0.06 logMAR). For subjects with a scalar power refractive error of 1.00 diopters or more, the average improvement was 0.1 logMAR. The observed changes in low-contrast resolution acuity were strongly correlated with off-axis astigmatism (Pearson r = 0.95; p < 0.0001), the J(180) cross-cylinder component (Pearson r = 0.82; p = 0.0034), and power scalar (Pearson r = -0.75; p = 0.0126). Conclusions. The results suggest that there are definite benefits in correcting even moderate amounts of off-axis refractive errors; in this study, as little as -1.50 DC of off-axis astigmatism gave improvements of up to a line in visual acuity. It may be even more pertinent for people who rely on optimal peripheral visual function, specifically those with central visual field loss; the use of open-field aberrometers could be clinically useful in rapidly determining off-axis refractive errors specifically for this patient group who are generally more challenging to refract.

  • 7.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Baskaran, Karthikeyan
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosén, Robert
    Biomedical & X-Ray Physics.
    Unsbo, Peter
    Biomedical & X-Ray Physics.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Clinical Impact of Objectively Determined Peripheral Refractive Error Correction on Low-Contrast Resolution AcuityManuskript (preprint) (Övrigt vetenskapligt)
  • 8.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Baskaran, Karthikeyan
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosén, Robert
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Unsbo, Peter
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    The Effect of Refractive-Correction on Peripheral Low-Contrast Resolution Acuity2012Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    Purpose: High-contrast resolution acuity in the peripheral retina has been shown to be sampling-limited, however, a recent study indicates that peripheral low-contrast resolution acuity (PLCRA) is degraded by imposition of optical defocus. On the other hand, it has not been investigated whether refractive errors present in the peripheral field of normal, emmetropic eyes are sufficient to degrade PLCRA. The aim of this study was to evaluate the effect of peripheral refractive-correction on PLCRA in young emmetropes.Methods: Low-contrast (10 %) resolution acuity was measured off-axis (20° nasal visual field) on the right eyes of 10 emmetropic subjects (age 22 ± 2 years), both with and without peripheral refractive correction. Central and peripheral refractive errors were acquired using an open-field COAS-HD VR aberrometer. Stimuli, consisting of low-contrast Gabor patches with a visible diameter of 2°, were presented on a CRT monitor situated 3.0 meters from the subjects. Resolution thresholds were determined using a 2-alternative forced-choice Bayesian algorithm.Results: All the subjects had off-axis astigmatism (against-the-rule) at 20° in the nasal visual field ranging from -1.00 DC to -2.00 DC; of which four had -1.00 DC, three had -1.25 DC, one had -1.50 DC and the remaining two had -2.00 DC. Two of the subjects with -1.25 DC had -0.50 DS to -0.75 DS spherical errors; the rest had purely cylindrical errors. The mean uncorrected and corrected low-contrast resolution acuities for all subjects were 0.92 logMAR and 0.86 logMAR respectively. This shows an improvement in resolution acuity of 0.06 logMAR (p = 0.028) after correction of off-axis refractive errors. However when grouped according to the amount of astigmatism, the -1.00 DC group showed no difference in acuity with correction, the -1.25 DC, -1.50 DC and -2.00 DC groups improved on average by 0.05, 0.14 and 0.16 logMAR respectively.Conclusions: Correction of off-axis refractive errors had a positive effect on low-contrast resolution thresholds in the peripheral visual field on the emmetropic subjects in this study. Moreover, the effects become appreciable only for those subjects having larger degrees of astigmatism. This suggests that optical factors influence peripheral visual tasks involving low-contrast. There may be benefits in correcting even moderate amounts of off-axis refractive errors, especially for people who rely on optimal peripheral visual function.

  • 9.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Holm, Victoria
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Baskaran, Karthikeyan
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Dynamic Stimulus Presentation Facilitates Peripheral Resolution Acuity2013Ingår i: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 54, artikel-id e-abstract 574Artikel i tidskrift (Övrigt vetenskapligt)
    Abstract [en]

    Purpose: Peripheral high-contrast resolution is sampling limited; the center to center spacing between ganglion cells ultimately limiting visual performance (Thibos et al., 1987). Although retinal image motion in the fovea has a detrimental effect on visual acuity, previous studies have suggested that retinal image motion may be advantageous in the peripheral visual field (Bex et al., 2003; Brown, 1972; Macedo et al., 2010). The aim of this study was to evaluate the effect of drift motion on peripheral resolution acuity.

    Methods: Peripheral high-contrast resolution acuity in a group of 26 subjects (age 23.5 ± 3.2 years) was initially determined using a 2-alternative forced-choice Bayesian algorithm; the threshold value defined as the spatial frequency resulting in a 75% correct response rate. The stimuli used to measure static visual acuity were stationary Gabor-patches with a visible diameter of 2° and were presented at 20° in the nasal visual field. We determined the percentage correct response rate for varying velocities using drifting Gabor patches of the same spatial frequency as determined during measurement of static visual acuity. The sine-wave gratings drifted within the Gaussian envelope at one of 10 angular velocities, varying from 0.2 to 2.0 degrees/second in 0.2 degrees/second steps.

    Results: Results showed an overall improvement in the subjects’ performance for all velocities. There was a significant difference in the percentage of correct responses between static stimulus presentation and for velocities of between 0.4 to 1.2 degrees/second (p < 0.05, One-way repeated measures ANOVA with Bonferroni post hoc tests). The average “correct response” for static stimulus presentation was 76 ± 2 %, improving to at least 85 % for velocities between 0.4 to 1.2 degrees/second. At velocities greater than 1.2 degrees/second performance was still better than for static stimulus presentation, but showed a gradual decline with increasing speed.

    Conclusions: In line with previous studies stimulus motion has a positive effect on peripheral high-contrast resolution acuity. Presenting moving stimuli may benefit patients who rely on peripheral visual function, such as those with central visual field loss subsequent to AMD.

  • 10.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosén, Robert
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Carius, Staffan
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för datavetenskap, fysik och matematik, DFM.
    Unsbo, Peter
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Dynamic Visual Acuity in the Peripheral Visual Field Using Gabor Patches2010Konferensbidrag (Refereegranskat)
    Abstract [en]

    Purpose:To evaluate dynamic visual acuity (DVA) in the peripheral visual field. This ability is important within the areas of sports, traffic safety, as well as for people with low vision; specifically those with central visual field loss. In this study we investigated both static- and dynamic visual acuity in the periphery of normally sighted observers using Gabor patches.

    Methods:DVA and static visual acuity (SVA) was measured on the right eye of normally sighted emmetropes. Stimuli consisted of high-contrast Gabor patches; sine wave gratings multiplied by a Gaussian hull with a diameter of 2º, with the sine gratings drifting at 1, 2, and 4 degrees per second. Stimuli were presented, using MATLAB and Psychophysics Toolbox, on one of seven CRT monitors at the following retinal eccentricities: 10, 20 and 30 degrees, nasally and temporally as well as in the fovea. Subjects were informed to maintain fixation on a central fixation object during measurements at eccentric locations. An Adaptive Bayesian algorithm was employed to determine resolution thresholds at each eccentricity.

    Results:The results show a trend towards both better static- and dynamic visual acuities for the temporal visual field at retinal eccentricities 20° and 30° compared to nasally. There appears to be a more rapid decrease in both static- and dynamic visual acuity with increasing eccentricity for the nasal visual field. In addition, we did not find any difference in DVA and SVA in the peripheral visual field for the velocities used in this study.

    Conclusions:Results of these first preliminary measurements suggest that dynamic visual acuity measured with drifting Gabor patches is greater in the temporal visual field for eccentricities 20 degrees or larger. To confirm these results more measurements need to be performed on a lager sample of subjects.

  • 11.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosén, Robert
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Unsbo, Peter
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Naso-temporal Asymmetry of Peripheral Static and Dynamic Visual Acuity2011Konferensbidrag (Refereegranskat)
    Abstract [en]

    Summary

    Static and dynamic visual acuity was evaluated in the peripheral visual field on normally sighted emmetropes. The results show a significant asymmetry for both static and dynamic visual acuity between the nasal and temporal visual fields.

     

    Introduction

    It is well known that visual performance thresholds decrease rapidly with increasing retinal eccentricity1. This reduction in performance can be attributed to both optical factors and reduced neural sampling2-3; the latter being the predominant limiting factor in the peripheral retina3.  Previous studies have shown that slowly moving stimuli are more easily resolved than stationary stimuli in the peripheral retina4. There is little evidence published regarding resolution thresholds for moving stimuli in more than a few limited directions in the visual field.     

    In this study, static visual acuity (SVA) and dynamic visual acuity (DVA) thresholds were measured at 10° intervals both nasally and temporally on healthy, young emmetropes. DVA was measured at angular velocities of 1 °/s and 2 °/s using drifting Gabor patches.  

     

    Discussion

    Static and dynamic visual acuity was measured on the right eye of emmetropic subjects. Results for SVA showed significantly better resolution in the temporal visual field compared with the nasal visual field at eccentricities 20° and beyond. The mean difference in acuity at 20° was approximately 0.2 LogMAR and at 30°, 0.3 LogMAR. The difference between the thresholds for DVA showed a similar naso-temporal asymmetry; the reduction in DVA paralleling the decrease in SVA for eccentricities 10° and beyond.  No significant differences were observed between averaged results of SVA and DVA for the eccentricities tested in this study.

     

    Conclusions

    The results of this study confirm previous research conducted by Frisén (1987) showing better resolution for static stimuli presented in the temporal visual field compared to the nasal visual field. We have found that this is also true for DVA.

  • 12.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Rosén, Robert
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Unsbo, Peter
    KTH, Royal Institute of Technology, Stockholm, Sweden.
    Gustafsson, Jörgen
    Linnéuniversitetet, Fakultetsnämnden för naturvetenskap och teknik, Institutionen för naturvetenskap, NV.
    Resolution of static and dynamic stimuli in the peripheral visual field.2011Ingår i: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 51, nr 16, s. 1829-1834Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    In a clinical setting, emphasis is given to foveal visual function, and tests generally only utilize static stimuli. In this study, we measured static (SVA) and dynamic visual acuity (DVA) in the central and peripheral visual field on healthy, young emmetropic subjects using stationary and drifting Gabor patches. There were no differences between SVA and DVA in the peripheral visual field; however, SVA was superior to DVA in the fovea for both velocities tested. In addition, there was a clear naso-temporal asymmetry for both SVA and DVA for isoeccentric locations in the visual field beyond 10° eccentricity. The lack of difference in visual acuity between static and dynamic stimuli found in this study may reflect the use of drift-motion as opposed to displacement motion used in previous studies.

  • 13.
    Lewis, Peter
    et al.
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Venkataraman, Abinaya Priya
    Royal Institute of Technology.
    Lundström, Linda
    Royal Institute of Technology.
    Contrast sensitivity in eyes with central scotoma: effect of stimulus drift2018Ingår i: Optometry and Vision Science, ISSN 1040-5488, E-ISSN 1538-9235, Vol. 95, nr 4, s. 354-361Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Significance

    In the field of visual rehabilitation of patients with central visual field loss, knowledge on how peripheral visual function can be improved is essential. This study presents measurements of peripheral dynamic contrast sensitivity (with optical correction) for off-axis viewing angles in subjects with central visual field loss.

    Purpose

    Subjects with central visual field loss (CFL) rely on a peripheral preferred retinal locus (PRL) for many visual tasks. It is therefore important to ascertain that contrast sensitivity (CS) is maximized in the PRL. This study evaluates the effect of stimulus motion, in combination with optical correction, on CS in subjects with CFL.

    Methods

    The off-axis refractive errors in the PRL of five young CFL subjects were measured with a COAS open-view Hartmann-Shack aberrometer. Low-contrast (25% and 10%) and high-contrast resolution acuity for stationary gratings was assessed with and without optical correction. High-contrast resolution was also measured for gratings drifting at 7.5 Hz (within a fixed Gaussian window). Furthermore, resolution CS was evaluated for both stationary and moving gratings with optical correction for a total of 2-3 spatial frequencies per subject.

    Results

    High-contrast resolution acuity was relatively insensitive to stimulus drift motion of 7.5 Hz, whereas CS for gratings of 0.5 cycles per degree improved with drift for all subjects. Furthermore, both high- and low-contrast static resolution improved with optical correction.

    Conclusions

    Just as for heathy eyes, stimulus motion of 7.5 Hz enhances CS for gratings of low spatial frequency also in the PRL of eyes with CFL. Concurrently, high contrast resolution is unaffected by the 7.5 Hz drift, but improves with off-axis optical correction. This highlights the importance of providing optimal refractive correction for subjects with CFL, and that stimulus motion can be used to further enhance CS at low spatial frequencies.

  • 14.
    Lundström, Linda
    et al.
    Royal Institute of Technology.
    Venkataraman, Abinaya Priya
    Royal Institute of Technology.
    Lewis, Peter
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Unsbo, Peter
    Royal Institute of Technology.
    Spatiotemporal contrast sensitivity in the 10 degrees visual field2016Ingår i: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 57, nr 12Artikel i tidskrift (Refereegranskat)
  • 15.
    Moreno, Laura Hernandez
    et al.
    Univ Minho, Portugal.
    Perdomo, Natacha Moreno
    Hosp Santa Maria Maior EPE, Portugal.
    Lima Ramos, Pedro
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO). Univ Minho, Portuga.
    Lewis, Peter
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Linhares, Joao
    Univ Minho, Portugal.
    Senra, Hugo
    Anglia Ruskin, UK.
    Santana, Rui
    Univ Nova Lisboa, Portugal.
    Macedo, António Filipe
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO). Univ Minho, Portugal.
    Visual and psychological outcomes in patients with and without low vision diagnosed with similar eye diseases - initial results.2018Ingår i: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 59, nr 9Artikel i tidskrift (Övrigt vetenskapligt)
  • 16.
    Santos, Diana
    et al.
    University of Minho, Portugal.
    Abrantes, João
    Universidade Lusófona de Humanidades e Tecnologias, Portugal.
    Lewis, Peter
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Macedo, António Filipe
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO). University of Minho, Portugal.
    Influence of the use of cane on the gait cycle of individuals who are blind2018Ingår i: The British Journal of Visual Impairment, ISSN 0264-6196, E-ISSN 1744-5809, Vol. 36, nr 3, s. 251-261Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this study was to perform a biomechanical characterization of the gait cycle in individuals who are blind. Five individuals with ages between 16 and 19 years participated in this study. The task consisted of walks of 12m measured in two conditions: (1) with cane and (2) wihtout cane; a total of 20 walks in each condition were performed. During walks, participants were monitored with a Vicon 3D-motion capture system. Spatialtemporal, kinematic, kinetic, and dynamic parameters were recorded and compared between the two conditions. We observed an interaction between the condition and ankle angular measures (p = .003); the interaction was due to differences induced by condition in instants ‘opposite toe off’ (p = .045) and ‘opposite initial contact’ (p = .019). We also obtained a significant difference in the negative ankle-joint-power measures between conditions (p = .044). This study showed that the use of cane changes the gait pattern in individuals who are blind. The subtle changes in ankle behaviour when walking with a cane, compared with no cane, suggest better application of the force during the initial stages of support leading to a more comfortable gait. This type of assessment of gait may be important to improve mobility training and rehabilitation strategies.

  • 17.
    Venkataraman, Abinaya Priya
    et al.
    Royal Institute of Technology.
    Lewis, Peter
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Lundström, Linda
    Royal Institute of Technology.
    Optical Correction and Stimulus Motion to Improve Vision in Eccentric Preferred Retinal Locus2016Ingår i: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 57, nr 12, artikel-id Meeting Abstract: 5175Artikel i tidskrift (Refereegranskat)
  • 18.
    Venkataraman, Abinaya Priya
    et al.
    KTH Royal Institute of Technology.
    Lewis, Peter
    Linnéuniversitetet, Fakulteten för Hälso- och livsvetenskap (FHL), Institutionen för medicin och optometri (MEO).
    Unsbo, Peter
    KTH Royal Institute of Technology.
    Lundström, Linda
    KTH Royal Institute of Technology.
    Peripheral resolution and contrast sensitivity: Effects of stimulus drift2017Ingår i: Vision Research, ISSN 0042-6989, E-ISSN 1878-5646, Vol. 133, s. 145-149Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Optimal temporal modulation of the stimulus can improve foveal contrast sensitivity. This studyevaluates the characteristics oftheperipheral spatiotemporal contrast sensitivity function in normal-sighted subjects.The purpose is to identify a temporal modulation that can potentially improve the remaining peripheral visual function in subjects with central visual field loss. High contrast resolution cut-off for grating stimuli with four temporal frequencies (0, 5, 10 and 15 Hz drift) was first evaluated in the 10° nasal visual field.Resolution contrast sensitivity for all temporal frequencies was then measured at four spatial frequencies between 0.5 cycles per degree (cpd) and the measured stationary cut-off. All measurements were performed with eccentric optical correction. Similar to foveal vision, peripheral contrast sensitivity is highest for a combination of low spatial frequency and 5 to 10 Hz drift. At higher spatial frequencies, there was a decrease in contrast sensitivity with 15 Hz drift.Despitethis decrease, the resolution cut-off did not vary largely between the different temporal frequencies tested. ​ Additional measurements of contrast sensitivity at 0.5 cpd and resolution cut-off for stationary (0 Hz) and 7.5 Hz stimuli performed at 10, 15, 20 and 25° in the nasal visual field also showed the same characteristics across eccentricities.

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