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  • 1.
    Andersson, Sofia
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Edman, Maria
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Bekmezian, A
    Holmberg, J
    Mircheff, A K
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Characterization of beta-hexosaminidase secretion in rabbit lacrimal gland2006In: Experimental eye research, Vol. 83, no 5, p. 1081-1088Article in journal (Refereed)
  • 2.
    Andersson, Sofia
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Hamm-Alvarez, S F
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Integrin adhesion in regulation of lacrimal gland acinar cell secretion2006In: Experimental eye research, Vol. 83, no 3, p. 543-553Article in journal (Refereed)
  • 3.
    Andersson, Sofia
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Sjögren, Elsie
    Magnusson, Caroline
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Sequencing, expression, and enzymatic characterization of beta-hexosaminidase in rabbit lacrimal gland and primary cultured acinar cells2005In: Glycobiology, Vol. 15 (3), p. 211-220Article in journal (Refereed)
  • 4. Bergmanson, J P G
    et al.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    The Lacrimal System2009In: Clinical Ocular Anatomy and Physiology / [ed] JPG Bergmanson, Houston, TX, USA: University of Houston Texas Eye Research and Technology Center , 2009, 16, p. 43-56Chapter in book (Other academic)
  • 5.
    Boström, Johanna
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Pettersson, Lovisa
    ,Karolinska Institutet.
    Baskaran, Karthikeyan
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Källmark, Fredrik
    Källmarkskliniken, Stockholm.
    Gierow, Peter
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Meibography: Inter-rater reliability2016In: 8th International Conference on the Tear Film & Ocular Surface: Basic Science and Clinical Relevance: Conference Program & Abstract Book, 2016, p. 47-Conference paper (Refereed)
    Abstract [en]

    Purpose. The tear film lipid layer holds an important role in maintaining the integrity and health of the anterior surface of the eye. The meibomian glands found in eyelids are responsible for producing most of the lipids of the tear film. Dysfunction of the meibomian glands leads to increased evaporation of tears, which may lead to dry eye. Meibography is a method used for assessing the drop out of meibomian glands. The aim of this study was to evaluate the reliability between two different examiners when rating meibography images. Methods. The Sirius 3D scheimpflug camera (C.S.O., Florence, Italy) was used to photograph the everted upper and lower eyelids of the right and left eye of 52 subjects. The grade of meibomian gland loss was subjectively graded using the five-grade Meiboscale (Pult, 2012) and the percentage of gland loss was calculated using Phoenix Meibography software (version 3.0.1.021, bon Optic VertriebsGmbH, Lübeck, Germany). Data was analyzed using MedCalc for Windows (version 16.4.3, MedCalc Software, Ostend, Belgium). Results. The inter-rater reliability for the Meiboscale grade of meibomian gland loss was calculated using weighted Cohen’s kappa (linear weights). The result for all 208 images was Kw = 0.542 (95 % CI 0.454 to 0.630), which indicates a moderate agreement. The inter-rater reliability for the percentage of meibomian gland loss was calculated using intraclass correlation coefficient. The result for all 208 images was ICC = 0.794 (95 % CI 0.737 to 0.839), which indicates a substantial agreement. Conclusions. Imaging is an invaluable tool when managing patients in clinical practice. When performing meibography to evaluate meibomian gland loss, using software to calculate the percentage of gland loss gives a better inter-rater agreement than subjective grading of the images.

  • 6.
    Carlsson, Stina K.
    et al.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Edman, Maria
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Delbro, Dick
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Gierow, Peter
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Adenosine A2 receptor presence, and synergy with cholinergic stimulation in rabbit lacrimal gland2010In: Current Eye Research, ISSN 0271-3683, E-ISSN 1460-2202, Vol. 35, no 6, p. 466-474Article in journal (Refereed)
    Abstract [en]

    PURPOSE: Secretion from the lacrimal gland is an important part of the well-being of the eye, and a central part in the search for treatment of dry eye syndrome. Adenosine has stimulatory effects on the lacrimal gland, and can potentiate the effect of the cholinergic agonist carbachol (Cch). The aim of the present study is to investigate the presence of the adenosine A(2) receptor subtypes A(2A) and A(2B) in the rabbit lacrimal gland, and to characterize their role in regulated acinar cell secretion.

    METHODS: Expression of the receptors was investigated using reverse transcriptase-PCR (RT-PCR) and immunofluorescence, and secretion effects were studied using a secretion assay in isolated lacrimal gland acinar cells.

    RESULTS: Presence of both receptors was detected by RT-PCR and immunofluorescence. The secretion assay revealed a minor effect of stimulation of the A(2) receptors, and a strong synergistic effect with the cholinergic agonist Cch. The synergistic effect was significantly reduced by the A(2B) antagonist PSB 1115, but not by the A(2A) antagonist SCH 58261, indicating that A(2B) is the receptor responsible for this potentiation.

    CONCLUSIONS: The study reveals the presence of the adenosine A(2) receptor subtypes as well as a role for them in lacrimal gland secretion, and especially in the synergy with purinergic and cholinergic stimulation.

  • 7.
    Carlsson, Stina K.
    et al.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Gierow, Peter
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    p38 mitogen-activated protein kinase modulates exocrine secretion in rabbit lacrimal gland2012In: Cellular & Molecular Biology Letters (Druk), ISSN 1425-8153, E-ISSN 1689-1392, Vol. 17, no 1, p. 1-10Article in journal (Refereed)
    Abstract [en]

    The lacrimal gland (LG) is an exocrine gland important for secretion of the tear film. The kinase p38 has important signal transduction functions, e.g. in gene transcription, but has previously not been known to modulate exocrine secretion. The aim of the current study was to investigate the role of p38 in carbachol (Cch)-induced LG secretion in LG acinar cells in vitro. Western blotting was used to determine the phosphorylation status of p38 and p42/44 and determine expression of p38 isoforms. To determine the effect of p38 inhibition on LG secretion, PD 169316, a general p38 inhibitor, and SB 239063, an inhibitor of p38α and β, were added to the cells prior to secretion measurements. The results revealed activation of p38 mediated by Cch stimulation and inhibition of Cch-induced secretion as a result of p38 inhibition. The inhibition was observed with PD 169316 isoforms, but not with SB 239063. The p38δ isoform was shown to have robust expression both by Western blotting of acinar cells and immunofluorescence of the whole gland. In conclusion, p38 activation mediates secretion in cholinergic stimulation of rabbit LG cells.

  • 8.
    Carlsson, Stina K.
    et al.
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    Wu, Kaijin
    Department of Pharmacology and Pharmaceutical Sciences, University of Southern California.
    Diaz, Daniel
    Department of Pharmacology and Pharmaceutical Sciences, University of Southern California.
    Hamm-Alvarez, Sarah F.
    Department of Pharmacology and Pharmaceutical Sciences, University of Southern California.
    Gierow, J. Peter
    Linnaeus University, Faculty of Science and Engineering, School of Natural Sciences.
    The adenosine A2a receptor is up-regulated in the lacrimal glands of NOD mice, an experimental model of Sjögren's syndromeManuscript (preprint) (Other academic)
  • 9.
    Edman, Maria
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Andersson, Sofia
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Delbro, Dick
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Functional expression of the adenosine A1 receptor in rabbit lacrimal gland.2008In: Experimental Eye Research, ISSN 0014-4835, E-ISSN 1096-0007, Vol. 86, no 1, p. 110-117Article in journal (Refereed)
  • 10. Ekblad, L
    et al.
    Jergil, B
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Purification of rabbit lacrimal gland plasma membranes by aqueous two-phase affinity partitioning2000In: Journal of chromatography B, Vol. 743, p. 397-401Article in journal (Refereed)
  • 11.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Relative proximity of domains in plasma membrane and in smooth endoplasmic reticulum from rat liver1994In: Methods in enzymology, Vol. 228, p. 512-522Article in journal (Refereed)
  • 12.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Andersson, Sofia
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Sjögren, Elsie
    Presence of alfa- and beta- integrin subunits in primary cultures of rabbit lacrimal gland acinar cells on a laminin matrix2002In: Advances in experimental medicine and biology, Vol. 506, p. 59-64Article in journal (Refereed)
  • 13.
    Gierow, Peter
    et al.
    Department of Biochemistry, University of Lund .
    Gierow, M
    Breeding biology of the Lapland Bunting Calcarius lapponicus in Lapland1991In: Ornis Svecica, ISSN 1102-6812, Vol. 1, p. 103-111Article in journal (Refereed)
  • 14.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Jergil, B
    A spectrophotometric method for the determination of glucose-6-phosphatase activity1980In: Analytical biochemistry, Vol. 101, no 2, p. 305-309Article in journal (Refereed)
  • 15.
    Gierow, Peter
    et al.
    Department of Biochemistry, University of Lund.
    Jergil, B
    Heterogeneity of smooth endoplasmic reticulum from rat liver studied by two-phase partitioning1989In: Biochemical Journal, ISSN 0264-6021, E-ISSN 1470-8728, Vol. 262, no 1, p. 55-61Article in journal (Refereed)
    Abstract [en]

    Smooth microsomal membranes, prepared from rat liver by sucrose-density-gradient centrifugation, were subfractionated by counter-current distribution in an aqueous two-phase system consisting of poly(ethylene glycol) and Dextran T500. A comparison of the distribution curves of marker enzymes, together with theoretically calculated curves, indicated the presence of at least five membrane subfractions, differing in the ratios of the marker enzymes. Glucose-6-phosphatase and arylesterase distributed in one manner, and NADPH-cytochrome c reductase and NADH-ferricyanide reductase in another. Evidence for further heterogeneities in the distribution of marker enzymes in smooth microsomes was obtained by analysing the membrane domain structure using a recently described method [Albertsson (1988) Q. Rev. Biophys. 21, 61-98]. Phenobarbital treatment did not influence the behaviour of the marker enzymes. 

  • 16.
    Gierow, Peter
    et al.
    UNIV LUND, CTR CHEM, DEPT BIOCHEM, S-22007 LUND 7, SWEDEN .
    Jergil, B
    Spectrophotometric method for glucose 6-phosphate phosphatase1982In: Methods in enzymology, Vol. 89, p. 44-47Article in journal (Refereed)
  • 17.
    Gierow, Peter
    et al.
    Lunds universitet.
    Jergil, B
    Albertsson, P-A
    Lateral heterogeneity of rat liver plasma membranes analysed by counter-current distribution1988In: Biochemical Journal, ISSN 0264-6021, E-ISSN 1470-8728, Vol. 249, p. 369-375Article in journal (Refereed)
    Abstract [en]

    The lateral heterogeneity of rat liver plasma membranes was examined by fragmentation and fractionation by counter-current distribution in an aqueous two-phase polymer system. The distribution pattern was analysed by plotting the relative specific activities of marker components against each other. By this analysis asialo-orosomucoid receptors were found in a domain separated from domains containing 5'-nucleotidase and leucine aminopeptidase by another domain devoid of these markers. 5'Nucleotidase and leucine aminopeptidase resided in adjacent but separate domains. The experimental data were compared with corresponding plots of markers in model membranes. The model membranes yielded plots of different shapes depending on marker distribution and fragment size. This method of analysis should be useful for examining the lateral heterogeneity also of other membranes. 

  • 18.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Jergil, B
    Albertsson, P-A
    Two-phase partitioning of rat liver plasma membranes1989In: Plenum Press In: Fisher, D. & Sutherland, I. (eds) Separations using aqueous phase systems. Applications in cell biology and biotechnology, New York, 1989Conference paper (Refereed)
  • 19.
    Gierow, Peter
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Kacz, Lucyna
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Effect of Age and Gender on Dry Eye according to Tests and Symptoms2018In: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 59, no 9Article in journal (Other academic)
  • 20.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Lambert, R W
    Mircheff, A K
    Fluid phase marker internalization by rabbit lacrimal acinar cells1995In: Experimental eye research, Vol. 60, p. 511-525Article in journal (Refereed)
  • 21.
    Gierow, Peter
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Larsson, Nathalie
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Boström, Johanna
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Comparison oF Different Tests for Evaluation of the Meibomian Glands2015In: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 56, no 7Article in journal (Other academic)
  • 22.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Mircheff, A K
    Role of protein kinases in regulation of apical secretion and basal-lateral membrane recycling traffic in reconstituted rabbit lacrimal gland acini1998In: Advances in experimental medicine and biology, Vol. 438, p. 187-190Article in journal (Refereed)
  • 23.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Sjögren, Elsie
    Magnusson, Caroline
    Tågerud, Sven
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Cloning, partial sequencing and expression of rabbit lacrimal gland beta-hexosaminidase2002In: Advances in Experimental Medicine and Biology, Vol. 506(pt A), p. 33-39Article in journal (Refereed)
  • 24.
    Gierow, Peter
    et al.
    Biochemistry, Chemical Centre, University of Lund.
    Sommarin, M
    Larsson, C
    Jergil, B
    Fractionation of rat liver plasma membrane regions by two-phase partitioning1986In: Biochemical journal, Vol. 235, p. 685-691Article in journal (Refereed)
    Abstract [en]

    Rat liver plasma membranes, enriched in blood-sinusoidal or bile-canalicular regions by differential andsucrose-gradient centrifugation, were further purified by partitioning in an aqueous polymer two-phasesystem. This method separates membranes according to differences in surface properties rather than size anddensity. A several-fold increase in the ratio of leucine aminopeptidase (a bile-canalicular marker) and5'-nucleotidase to asialo-orosomucoid binding (a blood-sinusoidal marker) was obtained in one fraction,whereas another fraction gave a 2-3-fold increase in ratio of blood-sinusoidal to bile-canalicular markers.Furthermore, the markers for both regions of the plasma membrane, as well as markers for Golgi membranesand lysosomes, showed a heterogeneous behaviour on counter-current distribution. 

  • 25.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Wood, R L
    Mircheff, A K
    Endocytosis and exocytosis in rabbit lacrimal gland acinar cells1994In: Advances in experimental medicine and biology, Vol. 350, p. 111-114Article in journal (Refereed)
  • 26.
    Gierow, Peter
    et al.
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Yang, T
    Bekmezian, A
    Norian, J
    Kim, S A
    Nelson, L
    Rafisolyman, S
    Wood, R L
    Mircheff, A K
    Endosomal Na,K-ATPase in lacrimal gland acinar cells. Correcting a case of mistaken identity1996In: American journal of physiology, Vol. 271, p. C1685-C1698Article in journal (Refereed)
  • 27. Hamm-Alvarez, S F
    et al.
    da Costa, S
    Yang, T
    Wei, X
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Mircheff, A K
    Cholinergic stimulation of lacrimal acinar cells promotes redistribution of membrane-associated kinesin and the secretory protein beta-hexosaminidase, and activation of soluble kinesin1997In: Experimental eye research, Vol. 64, p. 141-156Article in journal (Refereed)
  • 28.
    Johansson, Oskar
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Gierow, Peter
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Morgan, Philip
    University of Manchester, UK.
    Trends in Swedish Contact Lens Prescribing 20172019Conference paper (Other academic)
    Abstract [en]

    Poster display 2: TRENDS IN SWEDISH CONTACT LENS PRESCRIBING 2017

    Presenter: Oskar Johansson

    Authors: OSKAR JOHANSSON1 , PHILP MORGAN2 , PETER GIEROW1

    Affiliation:1) Linnaeus University 2) University of Manchester

    Key words: Contact lens, fitting, lens type

    Purpose: The purpose was to evaluate the trends of contact lens prescribing among Swedish optometrists in 2017.

    Methods: A standardized survey form developed by Morgan er al. was distributed to Swedish optometrists usingtheir professional organizations, optometry chains, direct email, and by hand directly. They were asked to fill out theform for the next ten contact lens patients after receiving the survey. Information was collected regarding the dayof fitting, age, sex, lens material, design, frequency of replacement, wear frequency, modality and type of caresystem. A weighting system is employed to account for the volume of activity undertaken by the respondents,calculated by the time period required to achieve 10 fits. All the forms and data were analyzed at the University of Manchester.

    Results: 57 forms were returned, including 562 fits. The mean age of the patients was 37 yrs, and 65 % were female.83 % were fitted for full-time wear and 27 % were managed as new fits. Soft contact lenses is the most fitted modalityand represents 97.8 % of all new fits and 93.6 % of all refits. Rigid contact lens fits represents therefore in grand total5.3 % with 2.2 % of the new fits and 6.4 % of the refits. About two-thirds of soft lenses prescribed were siliconehydrogels. Of the different designs, spherical lenses were most widely fitted, with toric lenses on at least one eyecoming right after. Extended wear accounts for 10.6 % of the fittings. Multi-purpose solutions were the most popularregimen prescribed at 99.4 %.

    Conclusions: When compared with data from Norway and Denmark, it is evident that daily disposables are morepopular in these countries (74 %), whereas in Sweden it is monthly replacements (58 %). Otherwise, the results aresimilar to what has been reported from other parts of the world.

  • 29.
    Johansson, Oskar
    et al.
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Morgan, Philip
    University of Manchester, UK.
    Gierow, Peter
    Linnaeus University, Faculty of Health and Life Sciences, Department of Medicine and Optometry.
    Trends in Swedish Contact Lens Prescribing 20172019In: Scandinavian Journal of Optometry and Visual Science, ISSN 1891-0882, E-ISSN 1891-0890, Vol. 12, no 1, p. 5-7Article in journal (Other academic)
    Abstract [en]

    Background: The purpose was to evaluate the trends of contact lens prescribing among Swedish optometrists in 2017.

    Materials and Methods: A standardized survey form was distributed to Swedish optometrists using their professional organisations, optometry chains, direct email, and by hand directly. They were asked to fill out the form for the ten contact lens fits performed after receipt of the survey form. Information was collected regarding age and sex of patient, fit/refit, lens design and material, modality and solution prescribed.

    Results: 57 forms were returned detailing 562 fits. The mean age of the patients was 37 yrs, and 65 % were female. 83 % were fitted for full-time wear and 27 % were managed as new fits. 94.7 % were soft contact lens fits and silicone hydrogel was the dominating material.

    Conclusions: When compared with data from Norway and Denmark, it is evident that daily disposables are more popular in these countries (74 %), whereas in Sweden it is monthly replacements (58 %). Otherwise, the results are similar to what has been reported from other parts of the world.

  • 30. Lambert, R W
    et al.
    Maves, C A
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Wood, R L
    Mircheff, A K
    Plasma membrane internalization and recycling in rabbit acinar cells1993In: Investigative ophthalmology & visual science, Vol. 34, p. 305-316Article in journal (Refereed)
  • 31. Mircheff, A K
    et al.
    Azzarolo, A M
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Kaswan, R L
    Maves, C M
    Warren, D W
    Wood, R L
    Understanding the causes of lacrimal insufficiency: Implications for treatment and prevention of dry eye syndrome1993In: Research to Prevent Blindness In: 12th Eye Research Seminar, New York, 1993Conference paper (Refereed)
  • 32. Mircheff, A K
    et al.
    Gierow, Peter
    University of Southern California School of Medicine, Los Angeles, California.
    Lee, L M
    Lambert, R W
    Akashi, R H
    Hofman, F M
    Class II antigen expression by lacrimal epithelial cells. An updated working hypothesis for antigen presentation by epithelial cells1991In: Investigative Ophthalmology and Visual Science, ISSN 0146-0404, E-ISSN 1552-5783, Vol. 32, no 8, p. 2302-2310Article in journal (Refereed)
    Abstract [en]

    It has been suggested that aberrant expression of Class II histocompatibility antigens (HLA) is involvedin T cell activation and leads to autoimmunity. Although Class II antigen expression was foundin various nonlymphoid tissues, including salivary glands, its expression on lacrimal epithelial cells hasnot been reported. In this study, 12 cadaver lacrimal glands were analyzed for HLA-DR and for thenumbers and distributions of T suppressor cells (Ts), T helper cells (Th), B cells, and macrophages.None of these cases exhibited the high numbers of inflammatory cells, tissue damage, and fibrosischaracteristic of Sjogren's syndrome. The HLA-DR-positive epithelial cells were detected in ten cases;they represented from less than 1% to more than 70% of the epithelial cells. In these ten positive cases,there were greater numbers of T cells per millimeter squared (229 ± 94 [mean ± the standard error ofthe mean]) than in the two HLA-DR-negative cases (37 ± 1 [mean ± range]). Three lacrimal glandspecimens tested were negative for immunoglobulin (Ig) G-bearing B cells, and two of the three specimenstested had IgA-bearing cells. Acinar cells were isolated from rat and rabbit lacrimal glands andcultured overnight in serum-free media supplemented with several potential mediators of Class IIantigen expression: interferon-7, carbachol, or isoproterenol. Freshly isolated cells did not expressClass II antigens at detectable levels, but in most experiments, they began to express the antigen evenin the absence of putative mediators. In light of results from recent studies of antigen presentation andepithelial cell membrane dynamics, these findings suggest a hypothesis in which Class II antigen-expressingepithelial cells present antigenic peptides that are generated in the intracellular compartmentsin communication with the basal-lateral membrane assembly and recycling pathway. 

  • 33. Mircheff, A K
    et al.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Wood, R L
    Exocrine acinar cell functions that may trigger local autoimmunity1994In: Kluwer In: Proceedings of the IVth International Symposium on Sjögren's Syndrome, Amsterdam, 1994Conference paper (Refereed)
  • 34. Mircheff, A K
    et al.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Wood, R L
    Traffic of major histocompability complex Class II molecules in rabbit lacrimal gland acinar cells1994In: Investigative ophthalmology & visual science, Vol. 35, p. 3943-3951Article in journal (Refereed)
  • 35. Mircheff, A K
    et al.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Wood, R L
    Akashi, R H
    Hofman, F M
    Cellular physiological hypothesis for autoantigen presentation and T cell activation1994In: Advances in experimental medicine and biology, Vol. 350, p. 651-654Article in journal (Refereed)
  • 36. Mircheff, A K
    et al.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Yang, T
    Hamm-Alvarez, S F
    Zhang, J
    Wood, R L
    Azzarolo, A M
    Warren, D W
    Zeng, H
    Okamoto, C
    Guo, Z
    Kaslow, H R
    Sjögren's autoimmunity: How pertubation of recognition in endomembrane traffic may provoke pathological recognition at the cell surface1998In: Journal of molecular recognition, Vol. 11, p. 40-48Article in journal (Refereed)
  • 37. Mircheff, A K
    et al.
    Lambert, R W
    Maves, C A
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Subcellular organization of ion transporters in lacrimal acinar cells1994In: Advances in experimental medicine and biology, Vol. 350, p. 79-86Article in journal (Refereed)
  • 38. Mircheff, A K
    et al.
    Yang, T
    Zhang, J
    Hongtao, Z
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Warren, D W
    Wood, R L
    Acinar cell basal-lateral membrane - endomembrane traffic may mediate interactions with both T-cells and B-cells1998In: Advances in experimental medicine and biology, Vol. 438, p. 63-68Article in journal (Refereed)
  • 39. Mircheff, Austin K.
    et al.
    Gierow, Peter
    University of Kalmar, School of Pure and Applied Natural Sciences.
    Wood, Richard L.
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