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• 1. Aaboe, L
University of Kalmar, Baltic Business School.
Incubator performance: An efficiency frontier analysis2008In: International Journal of Business Innovation and Research, ISSN 1751-0252, E-ISSN 1751-0260, Vol. 2, no 4, p. 354-380Article in journal (Refereed)

Assessments and evaluations of incubators has been a topic of discussion for as long as incubators have been in existence due to the fact that there has not been an agreement on how to determine good performance. This paper demonstrates the use of Data Envelopment Analysis (DEA) when studying performance of incubators. More specifically, it does so within the four dimensions of cooperation with universities, business networks, external funding and competence development on a sample of 16 Swedish incubators. We show that DEA enables us to measure non-numerical dimensions, and to simultaneously take into account the efforts made by both the incubator and the outcomes. Moreover, DEA provides benchmarks and, based on a model that divides the incubators into four different groups, illustrates the difference between the benchmark and the incubators' current situation.

• 2. Aaboen, L
University of Kalmar, Baltic Business School.
Critical dimensions for technology transfer Incubator-facilitated links between finance, academia and NTBFs2008In: International Journal of Management and Enterprise Development, ISSN 1468-4330, E-ISSN 1741-8127, Vol. 5, no 3, p. 331-335Article in journal (Refereed)

This paper explores incubator facilitation of technology transfer for their New Technology-Based Firms (NTBFs). Empirical evidence gathered from six interviews with incubator managers, together with a survey of 131 NTBFs in incubators in Sweden, in 2005, and the findings made in a survey of 273 NTBFs situated inside-and-outside Science Parks in 1999, are used for the exploration. It is suggested that incubators do facilitate technology transfer for their NTBFs. It is further suggested that the development towards increased ability to facilitate technology transfer will continue as a results of the efforts made on the incubator and systemic level.

• 3.
University of Kalmar, School of Pure and Applied Natural Sciences.
Vill kunder handla receptfria läkemedel i dagligvaruhandeln?: - En enkätundersökning2008Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpStudent thesis

Sammanfattning

I Sverige har det statliga apoteketsmonopolet ifrågasatts en längre tid och regeringen utreder nu möjligheten att konkurrensutsätta läkemedelsförsäljningen. Det har även föreslagits i den statliga utredningen (SOU 2008:4 del 2) att ett begränsat sortiment av OTC läkemedel (over the counter = receptfria läkemedel) ska få säljas i dagligvaruhandeln utan farmaceutiskt kompetenskrav. Vid korrekt användning och tillgång till rätt rådgivning kan OTC läkemedel vara till en stor hjälp för den enskilde individen vid egenvård och därigenom också bidra till avlastning på sjukvårdens resursers. Vid felanvändning av OTC läkemedel (över/underdosering, fel indikationsområde etc.), kan de istället få motsatt effekt. Syftet med denna enkätstudie var därför att utforska om konsumenter av OTC läkemedel i Sverige önskar få tillgång till dessa läkemedel i t ex livsmedelsbutiker, där de inte har tillgång till personlig farmaceutisk rådgivning, vidare var avsikten att undersöka hur de i dagligvaruhandeln önskade få läkemedelsinformation. I februari 2008 gjordes en enkätstudie i Västervik som inkluderade 48 deltagare varav 29 kvinnor och 19 män. Studien visade att 71 % av deltagarna hade en positiv inställning till att köpa OTC läkemedel i livsmedelsbutiker, 58 % skulle skaffa information genom läkemedelsförpackning och bipacksedel i kombination med att de tidigare använt läkemedlet. Önskan om tillgång till personlig rådgivning på inköpsstället var störst i åldern ≤ 35 år, där 38 % ansåg sig vilja det. Slutsats av studien är att majoriteten vill kunna handla OTC läkemedel i dagligvaruhandeln och information skulle de få främst från läkemedelsförpackning/bipacksedel i kombination med erfarenheter från tidigare användning.

2008:F5

• 4. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
SEARCH FOR HIGH-ENERGY MUON NEUTRINOS FROM THE "NAKED-EYE" GRB 080319B WITH THE IceCube NEUTRINO TELESCOPE2009In: Astrophysical Journal, ISSN 0004-637X, E-ISSN 1538-4357, Vol. 701, no 2, p. 1721-1731Article in journal (Refereed)

We report on a search with the IceCube detector for high-energy muon neutrinos from GRB 080319B, one of the brightest gamma-ray bursts (GRBs) ever observed. The fireball model predicts that a mean of 0.1 events should be detected by IceCube for a bulk Lorentz boost of the jet of 300. In both the direct on-time window of 66 s and an extended window of about 300 s around the GRB, no excess was found above background. The 90% CL upper limit on the number of track-like events from the GRB is 2.7, corresponding to a muon neutrino fluence limit of 9.5 x 10(-3) erg cm(-2) in the energy range between 120 TeV and 2.2 PeV, which contains 90% of the expected events.

• 5. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
Extending the Search for Neutrino Point Sources with IceCube above the Horizon2009In: Physical Review Letters, ISSN 0031-9007, E-ISSN 1079-7114, Vol. 103, no 22, p. Article ID: 221102-Article in journal (Refereed)

Point source searches with the IceCube neutrino telescope have been restricted to one hemisphere, due to the exclusive selection of upward going events as a way of rejecting the atmospheric muon background. We show that the region above the horizon can be included by suppressing the background through energy-sensitive cuts. This improves the sensitivity above PeV energies, previously not accessible for declinations of more than a few degrees below the horizon due to the absorption of neutrinos in Earth. We present results based on data collected with 22 strings of IceCube, extending its field of view and energy reach for point source searches. No significant excess above the atmospheric background is observed in a sky scan and in tests of source candidates. Upper limits are reported, which for the first time cover point sources in the southern sky up to EeV energies.

• 6. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
First Neutrino Point-Source Results from the 22 String Icecube Detector2009In: The Astrophysical Journal Letters, ISSN 2041-8205, Vol. 701, no 1, p. L47-L51Article in journal (Refereed)

We present new results of searches for neutrino point sources in the northern sky, using data recorded in 2007-2008 with 22 strings of the IceCube detector (approximately one-fourth of the planned total) and 275.7 days of live time. The final sample of 5114 neutrino candidate events agrees well with the expected background of atmospheric muon neutrinos and a small component of atmospheric muons. No evidence of a point source is found, with the most significant excess of events in the sky at 2.2Ïƒ after accounting for all trials. The average upper limit over the northern sky for point sources of muon-neutrinos with E â€“2 spectrum is ##IMG## [http://ej.iop.org/images/1538-4357/701/1/L47/apjl318527ieqn1.gif] $E^2\,Φ _ν _μ < 1.4 \,\,\times\,\, 10^-11\; \mathrmTeV\;cm^-2\;\mathrms^-1$ , in the energy range from 3Â TeV to 3Â PeV, improving the previous best average upper limit by the AMANDA-II detector by a factor of 2.

• 7. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
Limits on a Muon Flux from Neutralino Annihilations in the Sun with the IceCube 22-String Detector2009In: Physical Review Letters, ISSN 0031-9007, E-ISSN 1079-7114, Vol. 102, no 20, p. Article ID: 201302-Article in journal (Refereed)

A search for muon neutrinos from neutralino annihilations in the Sun has been performed with the IceCube 22-string neutrino detector using data collected in 104.3 days of live time in 2007. No excess over the expected atmospheric background has been observed. Upper limits have been obtained on the annihilation rate of captured neutralinos in the Sun and converted to limits on the weakly interacting massive particle (WIMP) proton cross sections for WIMP masses in the range 250-5000 GeV. These results are the most stringent limits to date on neutralino annihilation in the Sun.

• 8. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
Determination of the atmospheric neutrino flux and searches for new physics with AMANDA-II2009In: Physical Review D, ISSN 1550-7998, E-ISSN 1550-2368, Vol. 79, no 10, p. Article ID: 102005-Article in journal (Refereed)

The AMANDA-II detector, operating since 2000 in the deep ice at the geographic South Pole, has accumulated a large sample of atmospheric muon neutrinos in the 100 GeV to 10 TeV energy range. The zenith angle and energy distribution of these events can be used to search for various phenomenological signatures of quantum gravity in the neutrino sector, such as violation of Lorentz invariance or quantum decoherence. Analyzing a set of 5511 candidate neutrino events collected during 1387 days of livetime from 2000 to 2006, we find no evidence for such effects and set upper limits on violation of Lorentz invariance and quantum decoherence parameters using a maximum likelihood method. Given the absence of evidence for new flavor-changing physics, we use the same methodology to determine the conventional atmospheric muon neutrino flux above 100 GeV.

• 9. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
Search for point sources of high energy neutrinos with final data from AMANDA-II2009In: Physical Review D, ISSN 1550-7998, E-ISSN 1550-2368, Vol. 79, no 6, p. Article ID: 062001-Article in journal (Refereed)

We present a search for point sources of high energy neutrinos using 3.8 yr of data recorded by AMANDA-II during 2000-2006. After reconstructing muon tracks and applying selection criteria designed to optimally retain neutrino-induced events originating in the northern sky, we arrive at a sample of 6595 candidate events, predominantly from atmospheric neutrinos with primary energy 100 GeV to 8 TeV. Our search of this sample reveals no indications of a neutrino point source. We place the most stringent limits to date on E(-2) neutrino fluxes from points in the northern sky, with an average upper limit of E(2)Phi(nu mu)+nu(tau)<= 5.2x10(-11) TeV cm(-2) s(-1) on the sum of nu(mu) and nu(tau) fluxes, assumed equal, over the energy range from 1.9 TeV to 2.5 PeV.

• 10. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
Solar Energetic Particle Spectrum on 2006 December 13 Determined by IceTop2008In: The Astrophysical Journal Letters, Vol. 689, no 1, p. L65-L68Article in journal (Refereed)

On 2006 December 13 the IceTop air shower array at the South Pole detected a major solar particle event. By numerically simulating the response of the IceTop tanks, which are thick Cerenkov detectors with multiple thresholds deployed at high altitude with no geomagnetic cutoff, we determined the particle energy spectrum in the energy range 0.6-7.6 GeV. This is the first such spectral measurement using a single instrument with a well-defined viewing direction. We compare the IceTop spectrum and its time evolution with previously published results and outline plans for improved resolution of future solar particle spectra.

• 11. Abbasi, R.
University of Kalmar, School of Pure and Applied Natural Sciences.
The IceCube data acquisition system: Signal capture, digitization, and timestamping2009In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, ISSN 0168-9002, E-ISSN 1872-9576, Vol. 601, no 3, p. 294-316Article in journal (Refereed)

IceCube is a km-scale neutrino observatory under construction at the South Pole with sensors both in the deep ice (InIce) and on the surface (IceTop). The sensors, called Digital Optical Modules (DOMs). detect, digitize and timestamp the signals from optical Cherenkov-radiation photons. The DOM Main Board (MB) data acquisition subsystem is connected to the central DAQ in the IceCube Laboratory (ICL) by a single twisted copper wire-pair and transmits packetized data on demand. Time calibration is maintained throughout the array by regular transmission to the DOMs of precisely timed analog signals, synchronized to a central GPS-disciplined clock. The design goals and consequent features, functional capabilities, and initial performance of the DOM MB, and the operation of a combined array of DOMs as a system, are described here. Experience with the first InIce strings and the IceTop stations indicates that the system design and performance goals have been achieved. (c) 2009 Elsevier B.V. All rights reserved.

• 12.
University of Kalmar, School of Pure and Applied Natural Sciences.
Hur skiljer sig traditionella från nyare generationer antipsykotika åt vad gäller biverkningen viktökning?2008Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpStudent thesis

Antipsykotiska läkemedel är basen för behandling av schizofreni, en psykisk sjukdom som uppträder redan hos unga människor. Symtomen vid schizofreni brukar delas in i positiva symtom (hallucinationer, vanföreställningar, paranoida tankar), negativa symtom (koncentrationssvårigheter, nedsatt språk- och tankeförmåga, minskat intresse för omgivningen, och initiativlöshet), samt kognitiva symtom (minnesproblem, problem med uppmärksamhet och koncentration).

Antipsykotiska läkemedel delas in i typiska (den äldre generationen) och atypiska (den nyare generationen) antipsykotika. För båda grupperna antipsykotiska läkemedel finns det risk för biverkningar. De vanligaste biverkningarna vid behandling med den äldre generationen antipsykotika är extrapyramidala biverkningar. En biverkning som förefaller mer specifik för de nya atypiska preparaten är viktökning, vilken även kan orsaka utveckling av många allvarliga sjukdomstillstånd.

Syftet med detta arbete var att jämföra typiska och atypiska antipsykotiska läkemedel med avseende på utveckling av viktökning.

För att få svar på min frågeställning har en litteraturstudie av fem vetenskapliga artiklar genomförts. De vetenskapliga artiklarna har hittats genom databassökningar i PubMed, medan övriga fakta har hämtats från andra källor.

Resultatet av de vetenskapliga artiklarna visar att det finns skillnader mellan traditionella och nyare generationer antipsykotika vad gäller tendens att orsaka viktökning. Med några undantag, är flera antipsykotiska läkemedel, som tillhör den nyare generationen, associerade med högre risk för utveckling av viktökning jämfört med den äldre generationen antipsykotika. Viktökning orsakas mest av klozapin, följt av olanzapin och risperidon. Quetiapin orsakar, i likhet med haloperidol, mindre viktökning.

På grund av detta faktum, forskar man numera kring orsakerna till denna skillnad för att förbättra biverkningsprofilen hos framtida antipsykotika.

2008:F2

• 13. Abdo, A. A.
University of Kalmar, School of Pure and Applied Natural Sciences. University of Kalmar, School of Pure and Applied Natural Sciences. University of Kalmar, School of Pure and Applied Natural Sciences.
The on-orbit calibration of the Fermi Large Area Telescope2009In: Astroparticle physics, ISSN 0927-6505, E-ISSN 1873-2852, Vol. 32, no 3-4, p. 193-219Article in journal (Refereed)

The Large Area Telescope (LAT) on-board the Fermi Gamma-ray Space Telescope began its on-orbit operations on June 23, 2008. Calibrations, defined in a generic sense, correspond to synchronization of trigger signals, optimization of delays for latching data, determination of detector thresholds, gains and responses, evaluation of the perimeter of the South Atlantic Anomaly (SAA), measurements of live time, of absolute time, and internal and spacecraft boresight alignments. Here we describe on-orbit calibration results obtained using known astrophysical sources, galactic cosmic rays, and charge injection into the front-end electronics of each detector. Instrument response functions will be described in a separate publication. This paper demonstrates the stability of calibrations and describes minor changes observed since launch. These results have been used to calibrate the LAT datasets to be publicly released in August 2009. (C) 2009 Elsevier B.V. All rights reserved.

• 14. Abdo, A. A.
University of Kalmar, School of Pure and Applied Natural Sciences.
Detection of 16 Gamma-Ray Pulsars Through Blind Frequency Searches Using the Fermi LAT2009In: Science, ISSN 0036-8075, E-ISSN 1095-9203, Vol. 325, no 5942, p. 840-844Article in journal (Refereed)

Pulsars are rapidly rotating, highly magnetized neutron stars emitting radiation across the electromagnetic spectrum. Although there are more than 1800 known radio pulsars, until recently only seven were observed to pulse in gamma rays, and these were all discovered at other wavelengths. The Fermi Large Area Telescope (LAT) makes it possible to pinpoint neutron stars through their gamma-ray pulsations. We report the detection of 16 gamma-ray pulsars in blind frequency searches using the LAT. Most of these pulsars are coincident with previously unidentified gamma-ray sources, and many are associated with supernova remnants. Direct detection of gamma-ray pulsars enables studies of emission mechanisms, population statistics, and the energetics of pulsar wind nebulae and supernova remnants.

• 15. Abdo, A. A.
University of Kalmar, School of Pure and Applied Natural Sciences.
FERMI OBSERVATIONS OF GRB 090902B: A DISTINCT SPECTRAL COMPONENT IN THE PROMPT AND DELAYED EMISSION2009In: Astrophysical Journal Letters, ISSN 2041-8205, Vol. 706, no 1, p. L138-L144Article in journal (Refereed)

We report on the observation of the bright, long gamma-ray burst (GRB), GRB 090902B, by the Gamma-ray Burst Monitor (GBM) and Large Area Telescope (LAT) instruments on-board the Fermi observatory. This was one of the brightest GRBs to have been observed by the LAT, which detected several hundred photons during the prompt phase. With a redshift of z = 1.822, this burst is among the most luminous detected by Fermi. Time-resolved spectral analysis reveals a significant power-law component in the LAT data that is distinct from the usual Band model emission that is seen in the sub-MeV energy range. This power-law component appears to extrapolate from the GeV range to the lowest energies and is more intense than the Band component, both below similar to 50 keV and above 100 MeV. The Band component undergoes substantial spectral evolution over the entire course of the burst, while the photon index of the power-law component remains constant for most of the prompt phase, then hardens significantly toward the end. After the prompt phase, power-law emission persists in the LAT data as late as 1 ks post-trigger, with its flux declining as t(-1.5). The LAT detected a photon with the highest energy so far measured from a GRB, 33.4(-3.5)(+ 2.7) GeV. This event arrived 82 s after the GBM trigger and similar to 50 s after the prompt phase emission had ended in the GBM band. We discuss the implications of these results for models of GRB emission and for constraints on models of the extragalactic background light.

• 16. Abdo, A. A.
University of Kalmar, School of Pure and Applied Natural Sciences.
A limit on the variation of the speed of light arising from quantum gravity effects2009In: Nature, ISSN 0028-0836, E-ISSN 1476-4687, Vol. 462, no 7271, p. 331-334Article in journal (Refereed)

A cornerstone of Einstein's special relativity is Lorentz invariance-the postulate that all observers measure exactly the same speed of light in vacuum, independent of photon-energy. While special relativity assumes that there is no fundamental length-scale associated with such invariance, there is a fundamental scale (the Planck scale, l(Planck) approximate to 1.62 x 10(-33) cm or E-Planck = M(Planck)c(2) approximate to 1.22 x 10(19) GeV), at which quantum effects are expected to strongly affect the nature of space-time. There is great interest in the (not yet validated) idea that Lorentz invariance might break near the Planck scale. A key test of such violation of Lorentz invariance is a possible variation of photon speed with energy(1-7). Even a tiny variation in photon speed, when accumulated over cosmological light-travel times, may be revealed by observing sharp features in gamma-ray burst (GRB) light-curves(2). Here we report the detection of emission up to similar to 31GeV from the distant and short GRB090510. We find no evidence for the violation of Lorentz invariance, and place a lower limit of 1.2E(Planck) on the scale of a linear energy dependence (or an inverse wavelength dependence), subject to reasonable assumptions about the emission (equivalently we have an upper limit of l(Planck)/1.2 on the length scale of the effect). Our results disfavour quantum-gravity theories(3,6,7) in which the quantum nature of space-time on a very small scale linearly alters the speed of light.

• 17. Abdo, A. A.
University of Kalmar, School of Pure and Applied Natural Sciences.
FERMI DISCOVERY OF GAMMA-RAY EMISSION FROM NGC 12752009In: Astrophysical Journal, ISSN 0004-637X, E-ISSN 1538-4357, Vol. 699, no 1, p. 31-39Article in journal (Refereed)

We report the discovery of high-energy (E > 100 MeV) gamma-ray emission from NGC 1275, a giant elliptical galaxy lying at the center of the Perseus cluster of galaxies, based on observations made with the Large Area Telescope (LAT) of the Fermi Gamma-ray Space Telescope. The positional center of the gamma-ray source is only approximate to 3' away from the NGC 1275 nucleus, well within the 95% LAT error circle of approximate to 5'. The spatial distribution of gamma-ay photons is consistent with a point source. The average flux and power-law photon index measured with the LAT from 2008 August 4 to 2008 December 5 are F-gamma = (2.10 +/- 0.23) x 10(-7) ph (>100 MeV) cm(-2) s(-1) and Gamma = 2.17 +/- 0.05, respectively. The measurements are statistically consistent with constant flux during the four-month LAT observing period. Previous EGRET observations gave an upper limit of F-gamma < 3.72 x 10(-8) ph (>100 MeV) cm(-2) s(-1) to the gamma-ray flux from NGC 1275. This indicates that the source is variable on timescales of years to decades, and therefore restricts the fraction of emission that can be produced in extended regions of the galaxy cluster. Contemporaneous and historical radio observations are also reported. The broadband spectrum of NGC 1275 is modeled with a simple one-zone synchrotron/synchrotron self-Compton model and a model with a decelerating jet flow.

• 18. Abdo, A. A.
University of Kalmar, School of Pure and Applied Natural Sciences.
FERMI/LARGE AREA TELESCOPE BRIGHT GAMMA-RAY SOURCE LIST2009In: Astrophysical Journal Supplement Series, ISSN 0067-0049, E-ISSN 1538-4365, Vol. 183, no 1, p. 46-66Article in journal (Refereed)

Following its launch in 2008 June, the Fermi Gamma-ray Space Telescope (Fermi) began a sky survey in August. The Large Area Telescope (LAT) on Fermi in three months produced a deeper and better resolved map of the gamma-ray sky than any previous space mission. We present here initial results for energies above 100 MeV for the 205 most significant (statistical significance greater than similar to 10 sigma) gamma-ray sources in these data. These are the best characterized and best localized point-like (i.e., spatially unresolved) gamma-ray sources in the early mission data.

• 19. Abdo, A. A.
University of Kalmar, School of Pure and Applied Natural Sciences.
A Population of Gamma-Ray Millisecond Pulsars Seen with the Fermi Large Area Telescope2009In: Science, ISSN 0036-8075, E-ISSN 1095-9203, Vol. 325, no 5942, p. 848-852Article in journal (Refereed)

Pulsars are born with subsecond spin periods and slow by electromagnetic braking for several tens of millions of years, when detectable radiation ceases. A second life can occur for neutron stars in binary systems. They can acquire mass and angular momentum from their companions, to be spun up to millisecond periods and begin radiating again. We searched Fermi Large Area Telescope data for pulsations from all known millisecond pulsars (MSPs) outside of globular clusters, using rotation parameters from radio telescopes. Strong gamma-ray pulsations were detected for eight MSPs. The gamma-ray pulse profiles and spectral properties resemble those of young gamma-ray pulsars. The basic emission mechanism seems to be the same for MSPs and young pulsars, with the emission originating in regions far from the neutron star surface.

• 20. Abdo, A. A.