This article presents a narrative perspective review of the state-of-the-art of destination marketing and management. The past 15 years of developments, stretching from technological advances enabling methodological progress and new consumer behavior to climate, health, and financial crises, require a reassessment of previous academic contributions and current practices. Referring back to the social origins of destinations, this article conceptualizes destinations as a heterogeneous space of flows and proposes future research linked to tourist demand and tourism supply, sustainability and resilience, technological shifts, and institutions. Finally, six broader streams of conversations suggest how to advance the marketing and management of destinations related to a destination ontology grounded in flows, with a focus on processes and action, stewardship and collaboration, resilient destinations, transient and permanent residents, as well as new instrumental technologies and augmented experiences.