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Självrapporterad hälsa efter hjärtstopp: Insomni som dolt hälsoproblem
Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences. (iCARE)ORCID iD: 0000-0001-5447-9721
2026 (Swedish)Doctoral thesis, comprehensive summary (Other academic)
Sustainable development
SDG 3: Ensure healthy lives and promote well-being for all at all ages
Alternative title
Self-reported Health After Cardiac Arrest : Insomnia as a Hidden Health Problem (English)
Abstract [en]

Aim

The overall aim of this thesis was to increase knowledge about self‑reported health among persons who have survived cardiac arrest, with a particular focus on insomnia, in order to contribute to improved care and the development valid measurement methods.

Methods

The thesis comprises four quantitative studies, all based on a shared data collection using questionnaires. The first three studies employed a non‑experimental design (I–III): Studies I and II were based on cross‑sectional data, whereas study III used longitudinal data. Study IV was a psychometric evaluation. The dataset originated from a Swedish survey study with data collected 6, 12, and 24 months after cardiac arrest (n = 212). For Study IV, additional participants from a neuropsychological sub-study of the TTM2 trial were included, allowing analyses of a total of 269 individuals. 

The questionnaire included background variables and seven validated instruments covering general, physical, mental, and social health, as well as life satisfaction and insomnia: EQ‑5D‑5L, Health Index, Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support, Satisfaction With Life Scale, and Minimal Insomnia Symptom Scale. Analyses included descriptive statistics, standard statistical tests, multiple regression analyses, mixed models, Rasch analysis, and ROC analysis. 

 

Results

Survivors generally reported good health. Six months after the cardiac arrest, the median scores were 80 on the EQ VAS and 29 on the Health Index. At the same time, symptoms of tiredness (37%), reduced energy (26%), pain (22%), and sleep difficulties (21%) were common. Mental health was overall good, although 18% of survivors showed signs of anxiety and 9% signs of depression. Social support and life satisfaction were rated high. Insomnia was common, and 20% met the criteria for clinical insomnia. Insomnia was strongly associated with self‑reported health. General health and depressive symptoms worsened over time, between 6 and 24 months. The Minimal Insomnia Symptom Scale showed good psychometric properties, and a score of ≥ 6 was deemed an appropriate cut‑off for clinical insomnia. 

Conclusion

People who survive cardiac arrest generally report good health, but many experience persistent specific health problems. Insomnia is a clear and long‑lasting issue with a strong association to self‑reported health. The Minimal Insomnia Symptom Scale is a reliable screening instrument, and the findings support systematic long‑term follow‑up of insomnia, physical, mental, and social health among cardiac arrest survivors. 

Place, publisher, year, edition, pages
Kalmar: Linnaeus University Press, 2026. , p. 95
Series
Linnaeus University Dissertations ; 616
Keywords [en]
Cardiac arrest, Health, Insomnia, Life satisfaction, Psychometrics, Self-reported health, Sleep
National Category
Health Sciences
Research subject
Health and Caring Sciences
Identifiers
URN: urn:nbn:se:lnu:diva-146163DOI: 10.15626/LUD.616.2026ISBN: 9789180824460 (print)ISBN: 9789180824477 (electronic)OAI: oai:DiVA.org:lnu-146163DiVA, id: diva2:2056436
Public defence
2026-05-29, Lapis, Universitetsplatsen 1 392 31, Kalmar, 09:15 (Swedish)
Opponent
Supervisors
Available from: 2026-04-30 Created: 2026-04-29 Last updated: 2026-04-30Bibliographically approved
List of papers
1. A comprehensive description of self-reported health and life satisfaction in cardiac arrest survivors
Open this publication in new window or tab >>A comprehensive description of self-reported health and life satisfaction in cardiac arrest survivors
2021 (English)In: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, E-ISSN 1757-7241, Vol. 29, no 1, article id 122Article in journal (Refereed) Published
Abstract [en]

Background

Self-reported health and life satisfaction are considered important outcomes in people surviving cardiac arrest. However, most previous studies have reported limited aspects on health, often based on composite scores, and few studies have focused on life satisfaction. Investigating health aspects with a broad and detailed perspective is important to increase the knowledge of life after cardiac arrest from the perspective of survivors. In addition, the knowledge of potential differences in health among survivors related to place of arrest (in-hospital cardiac arrest; IHCA or out-of-hospital cardiac arrest; OHCA) is scarce. The aim was to describe and compare self-reported health and life satisfaction in IHCA and OHCA survivors.

Methods

This observational cross-sectional study included adult cardiac arrest survivors six months after resuscitation, treated at five Swedish hospitals between 2013 and 2018. Participants received a study specific questionnaire including Health Index (HI), EQ-5D 5 Levels (EQ-5D-5L), Minimal Insomnia Sleeping Scale (MISS), Multidimensional Scale of Perceived Social Support (MSPSS), Hospital Anxiety and Depression Scale (HADS), and Satisfaction With Life Scale (SWLS). In order to present characteristics descriptive statistics were applied. The Mann-Whitney U test, chi-square test or Fishers' exact test were used to compare differences in self-reported health and life satisfaction between in-hospital- and out-of-hospital cardiac arrest survivors

Results

In total, 212 survivors participated. Based on scale scores and general measures, the median scores of health and life satisfaction among survivors were high: HI total = 29, EQ VAS = 80, and SWLS = 20. According to HI, most problems were reported for tiredness (37.3 %) and strength (26.4 %), while pain/discomfort (57.5 %) and anxiety/depression (42.5 %) where most common according to EQ-5D-5L. Except for EQ-5D-5L mobility (p = 0.023), MSPSS significant other (p = 0.036), and MSPSS family (p = 0.043), no health differences in relation to place of arrest were identified.

Conclusions

Although general health and life satisfaction were good among cardiac arrest survivors, several prevalent health problems were reported regardless of place of arrest. To achieve an improved understanding of health in cardiac arrest survivors, it is important to assess specific symptoms as a complement to composite scores of general, physical, emotional, and social health.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2021
Keywords
Cardiac Arrest, Health, Heart arrest, Life satisfaction, Quality of life
National Category
Nursing
Research subject
Health and Caring Sciences, Nursing
Identifiers
urn:nbn:se:lnu:diva-106782 (URN)10.1186/s13049-021-00928-9 (DOI)000687145600001 ()34419126 (PubMedID)2-s2.0-85113755171 (Scopus ID)2021 (Local ID)2021 (Archive number)2021 (OAI)
Available from: 2021-09-03 Created: 2021-09-03 Last updated: 2026-04-29Bibliographically approved
2. Is insomnia associated with self-reported health and life satisfaction in cardiac arrest survivors?: A cross-sectional survey
Open this publication in new window or tab >>Is insomnia associated with self-reported health and life satisfaction in cardiac arrest survivors?: A cross-sectional survey
Show others...
2023 (English)In: Resuscitation Plus, E-ISSN 2666-5204, Vol. 15, article id 100455Article in journal (Refereed) Published
Abstract [en]

Background: Insomnia symptoms seem to be common in cardiac arrest survivors but their associations with important outcomes such as self reported health and life satisfaction have not previously been reported during the early post-event period. Therefore, the aim of the study was to investigate whether symptoms of insomnia are associated with self-reported health and life satisfaction in cardiac arrest survivors six months after the event.Methods: This multicentre cross-sectional survey included cardiac arrest survivors =18 years. Participants were recruited six months after the event from five hospitals in southern Sweden, and completed a questionnaire including the Minimal Insomnia Symptom Scale, EQ-5D-5L, Health Index, Hospital Anxiety and Depression Scale, and Satisfaction With Life Scale. Data were analysed using the Mann-Whitney U test, linear regression, and ordinal logistic regression. The regression analyses were adjusted for demographic and medical factors.Results: In total, 212 survivors, 76.4% males, with a mean age of 66.6 years (SD = 11.9) were included, and of those, 20% reported clinical insomnia. Insomnia was significantly associated with all aspects of self-reported health (p < 0.01) and life satisfaction (p < 0.001), except mobility (p = 0.093), self-care (p = 0.676), and usual activities (p = 0.073).Conclusion: Insomnia plays a potentially important role for both health and life satisfaction in cardiac arrest survivors. Screening for sleep problems should be part of post cardiac arrest care and follow-up to identify those in need of further medical examination and treatment.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Health, Sleep, Quality of life, Life satisfaction, Psychological distress, Insomnia
National Category
Nursing
Research subject
Health and Caring Sciences, Nursing
Identifiers
urn:nbn:se:lnu:diva-125039 (URN)10.1016/j.resplu.2023.100455 (DOI)001069174600001 ()37662641 (PubMedID)2-s2.0-85169592850 (Scopus ID)
Available from: 2023-10-05 Created: 2023-10-05 Last updated: 2026-04-29Bibliographically approved
3. Health with focus on insomnia in cardiac arrest survivors: a 24-month longitudinal stud
Open this publication in new window or tab >>Health with focus on insomnia in cardiac arrest survivors: a 24-month longitudinal stud
(English)Manuscript (preprint) (Other academic)
Abstract [en]

Aim: To explore longitudinal variations in self-reported health and life satisfaction, with a particular focus on insomnia, over a 24-month period following cardiac arrest. 

 

Methods and results: This longitudinal multicentre study included 212 cardiac arrest survivors recruited from five hospitals in Sweden. Data were collected via postal questionnaires at 6, 12, and 24 months post-arrest. Measures included EQ VAS and Health Index (HI), Hospital Anxiety and Depression Scale (HADS), Satisfaction With Life Scale (SWLS), and Minimal Insomnia Symptom Scale (MISS). Linear mixed-effects models and McNemar’s test were used to examine changes over time.  General health measured by EQ VAS remained stable, whereas HI declined significantly over time. Depressive symptoms increased significantly, while anxiety and life satisfaction showed no significant changes. No changes in insomnia symptoms were shown between the tree assessments, while a significant declined was precent in non-restorative sleep between the 6- and 24-months assessments. At the 24-month assessment, 25.6% of participants reported clinical insomnia. 

 

Conclusion: Although most cardiac arrest survivors reported good health and life satisfaction, a substantial proportion experienced persistent problems, particularly insomnia. These difficulties were not transient but appeared to persist or worsen over time, potentially undermining recovery.

Keywords
Cardiac Arrest, Insomnia Health, Heart arrest, Life satisfaction
National Category
Health Sciences
Research subject
Health and Caring Sciences
Identifiers
urn:nbn:se:lnu:diva-146162 (URN)
Available from: 2026-04-28 Created: 2026-04-28 Last updated: 2026-04-29
4. Measurement properties of the Minimal Insomnia Symptom Scale (MISS) among cardiac arrest survivors - A Rasch evaluation study
Open this publication in new window or tab >>Measurement properties of the Minimal Insomnia Symptom Scale (MISS) among cardiac arrest survivors - A Rasch evaluation study
Show others...
2025 (English)In: Resuscitation Plus, E-ISSN 2666-5204, Vol. 22, article id 100876Article in journal (Refereed) Published
Abstract [en]

Introduction: Cardiac arrest (CA) survivors often face significant health challenges, including insomnia, which can adversely affect their healthrelated quality of life. The Minimal Insomnia Symptom Scale (MISS) is a brief, self-reported instrument designed to screen for insomnia. This study aimed to identify the measurement properties of the MISS in CA survivors and to explore a relevant cut-off score. Methods: Data were collected from two studies: a health survey of CA survivors and a sub-study of a randomized controlled trial (RCT) on targeted temperature management (TTM2). A total of 269 CA survivors participated, with 212 from the survey and 57 from the RCT, the data was collected 6- 7 months after CA. The MISS was evaluated using the polytomous Rasch model, focusing on model fit, local independence, response category functioning, targeting, reliability, and differential item functioning (DIF). Results: In total, 212 participants were males and 57 females, with a mean age of 66 years. Overall, 51% had survived in-hospital CA and 49% outof-hospital CA. The MISS exhibited acceptable model fit and targeting, with no disordered thresholds or DIF for age, sex, or place of arrest. The reliability was acceptable. The suggested optimal cut-off score for identifying insomnia was >6 points. Conclusions: The findings indicate that MISS is a valid and reliable screening instrument for insomnia in CA survivors. These results support the use of MISS for screening insomnia in CA survivors.

Place, publisher, year, edition, pages
Elsevier, 2025
Keywords
Heart arrest, Insomnia, Psychometrics, Rasch model, Sleep, Validation study
National Category
Nursing
Research subject
Health and Caring Sciences, Nursing
Identifiers
urn:nbn:se:lnu:diva-137190 (URN)10.1016/j.resplu.2025.100876 (DOI)001428041900001 ()39990956 (PubMedID)2-s2.0-85216768108 (Scopus ID)
Available from: 2025-03-19 Created: 2025-03-19 Last updated: 2026-04-29Bibliographically approved

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12 2 of 2
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