This chapter documents the diverse motivations for entering sex work, and transnational Cameroonian sex workers’ experiences with clients in N’Djamena, the capital of Chad. It explores their sex work practices, the risks as well as the various coping strategies they have adopted to handle the neoliberal economic context in which they operate. Cameroonian sex workers in Chad have created individual innovative, entrepreneurial strategies to adapt themselves to and to cope with the neoliberal economic and political context. While a conjuncture between a lack of marketable skills and economic crises in their home countries have pushed them into the sex trade, it allows them to make sufficient money to take care of themselves and their families and bears the chance to overcome the suffering, hardship and oppression that they face in their everyday lives.