This chapter discusses recent trends in management of postuse wood products and gives an overview of benefits and constraints associated with effective end-of-life management of wood. It highlights the implications of postuse wood management from resource efficiency and climate perspectives. Primary energy and GHG balances are important metrics to understand the resource efficiency of climate change mitigation strategies involving postuse wood products. The chapter describes mechanisms through which postuse management of recovered wood materials can affect primary energy use and GHG impacts of wood products. To further understand the implications of different postuse management options for wood products, we then explore several quantitative scenarios. There is potential for efficient management of postuse wood products by directing these resources to cascade uses including reuse, recycling, and energy recovery. This can offer significant opportunities to improve resource efficiency and reduce greenhouse gas emissions in the built environment.