We find that if a Fourier multiplier is continuous from LΦ1 to LΦ2, then it is also continuous from M Φ1,Ψ to M Φ2,Ψ, where Φ1, Φ2, Ψ are quasi-Young functions and Φ1 fulfills the ∆2-condition. This result is applied to show that Mihlin’s Fourier multiplier theorem and Hörmander’s improvement hold in certain Orlicz modulation spaces. Lastly, we show that the Fourier multiplier with symbol m(ξ) = eiµ(ξ), where µ is homogeneous of order α, is bounded on quasi-Banach Orlicz modulation spaces of order r, assuming r ∈(d/(d + 2), 1] and α ∈(d(1 − r)/r, 2].