Nailed connections are commonly employed for connecting sheathings to the framing used in shear walls. Although many aspects of such connections have been investigated thoroughly within the research community generally, the effect the loading direction has on connections of this sort has been much less investigated. In the present study experimental tests were carried out for determining in detail the effects the loading has on different sheathing-to-framing connections. The results obtained indicated the degree of loading to which a nail fastened to an oriented strand board (OSB) sheathing is subjected to not be strongly affected by which of the two main loading directions is involved, but that the effects of loading direction are found to be much greater if the timber element in question is also included in the testing carried out. The dependency of the loading effect on the loading direction at different loading stages and for different directions - parallel to the fibres, perpendicular to them, at some angle between these two main directions - was investigated here.