This investigation has established the Possibility of Producing Particleboard from Cotton Stems (Gossypium sp.) left after cotton picking. This product has good physical-( moisture content, density, absorption and cross-swelling after 24 hours) and mechanical Properties (binding strength and cross-tensile strength) and is very economical. Although the mean of values for cross swelling and absorption were higher than the mean of values for cross swelling and absorption of standard particleboards which have been determined according to European Norms EN (DIN, 1999). these values were satisfactory, because we didn't use the water proofing material (Parafin emulsion) when producing the particleboard which is normally used in Europe (between 0.25-1 % according to the dry weight of the chips) Haygreen et. al., (2003).